A simple method for constructing confounded designs for mixed factorial experiments

This paper presents the sinplesr procedure that uses wodular aryithmetic for constructing confounded designs for mixed factorial experiments. The present procedure and the classical one for confounding in symmetrical factorial experiments are both at the same mathema.tical level. The present procedure is written for

practitioners and is lllustrared with several examples.     

Bayesian prediction bounds for the pareto lifetime model

Suppose that the length of time in years for which a business operates until failure has a Pareto distribution. Let x₁ ≤ x₂ x₃ ≤…≤z_k denote the survival lifetimes of the first k of a random sample of n businesses. Bayesian predictions are to be made on the ordered failure times of t h e remaining (n-k) businesses, using the conditional probability density function. Examples are given to illustrate our results.     

A Measure of partial association between disease and genotype for the two-parent problem

The two-parent disease-genotype association problem is studied from the point of view of a coefficient of association between the disease phenotype of the child and the disease phenotypes of the parents, in the presence of some genotypic information about the parents. This coefficient of partial association is derived, and certain tests of hypotheses are constructed. The results are shown to be useful in estimation of recurrence risks, and in understanding the nature of the association between child and parental disease phenotypes.     

A new rank test for the K-Sample problem

The treatment sum of squares in the one-way analysis of variance can be expressed in two different ways: as a sum of comparisons between each treatment and the remaining treatments combined, or as a sum of comparisons between the treatments two at a time. When comparisons between treatments are made with the Wilcoxon rank sum statistic, these two expressions lead to two different tests; namely, that of Kruskal and Wallis and one which is essentially the same as that proposed by Crouse (1961,1966). The latter statistic is known to be asymptotically distributed as a chi-squared variable when the numbers of replicates are large. Here it is shown to be asymptotically normal when the replicates are few but the number of treatments is large. For all combinations of numbers of replicates and treatments its empirical distribution is well approximated by a beta distribution     

Using power transformations when approximating quantiles

Estimators are obtained tor quantiles of survival distributions. This is accomplished by approximating Lritr distribution of the transtorrneri data, where the transformation used is that of Box and Cox (1964). The normal approximation as in Box and Cox and, in addition, the extreme value approximation are considered. More generally, to use the methods given, the approximating distribution must come from a location-scale family. For some commonly used survival random variables T the performance of the above approximations are evaluated in terms of the ratio of the true quantiles of T to the estimated one, in the long run. This performance is also evaluated for lower quantiles using simulated lognormai, Weibull and gamma data. Several examples are given to illustrate the methodology herein, including one with actual data.     

Bayesian analysis of a multiple-recapture model

In the Bayesian analysis of a multiple-recapture census, different diffuse prior distributions can lead to markedly different inferences about the population size N. Through consideration of the Fisher information matrix it is shown that the number of captures in each sample typically provides little information about N. This suggests that if there is no prior information about capture probabilities, then knowledge of just the sample sizes and not the number of recaptures should leave the distribution of Nunchanged. A prior model that has this property is identified and the posterior distribution is examined. In particular, asymptotic estimates of the posterior mean and variance are derived. Differences between Bayesian and classical point and interval estimators are illustrated through examples.     

Estimation of a process capability index for inverse gaussian distribution

In this article, interval estimates of Clements' process capability index are studied through bootstrapping when the underlying distribution is Inverse Gaussian. The standard bootstrap, the percentile bootstrap, and the bias-corrected percentile bootstrap confidence intervals are compared.     

Umvu estimators for the population mean and variance based on random effects models for lognormal data

Cross-classified data are often obtained in controlled experimental situations and in epidemiologic studies. As an example of the latter, occupational health studies sometimes require personal exposure measurements on a random sample of workers from one or more job groups, in one or more plant locations, on several different sampling dates. Because the marginal distributions of exposure data from such studies are generally right-skewed and well-approximated as lognormal, researchers in this area often consider the use of ANOVA models after a logarithmic transformation. While it is then of interest to estimate original-scale population parameters (e.g., the overall mean and variance), standard candidates such as maximum likelihood estimators (MLEs) can be unstable and highly biased. Uniformly minimum variance unbiased (UMVU) cstiniators offer a viable alternative, and are adaptable to sampling schemes that are typiral of experimental or epidemiologic studies. In this paper, we provide UMVU estimators for the mean and variance under two random effects ANOVA models for logtransformed data. We illustrate substantial mean squared error gains relative to the MLE when estimating the mean under a one-way classification. We illustrate that the results can readily be extended to encompass a useful class of purely random effects models, provided that the study data are balanced.