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11.
Heitor de Oliveira Duarte Enrique Lopez Droguett Márcio das Chagas Moura Elainne Christine de Souza Gomes Constança Barbosa Verônica Barbosa Moacyr Araújo 《Risk analysis》2014,34(5):831-846
We developed a stochastic model for quantitative risk assessment for the Schistosoma mansoni (SM) parasite, which causes an endemic disease of public concern. The model provides answers in a useful format for public health decisions, uses data and expert opinion, and can be applied to any landscape where the snail Biomphalaria glabrata is the main intermediate host (South and Central America, the Caribbean, and Africa). It incorporates several realistic and case‐specific features: stage‐structured parasite populations, periodic praziquantel (PZQ) drug treatment for humans, density dependence, extreme events (prolonged rainfall), site‐specific sanitation quality, environmental stochasticity, monthly rainfall variation, uncertainty in parameters, and spatial dynamics. We parameterize the model through a real‐world application in the district of Porto de Galinhas (PG), one of the main touristic destinations in Brazil, where previous studies identified four parasite populations within the metapopulation. The results provide a good approximation of the dynamics of the system and are in agreement with our field observations, i.e., the lack of basic infrastructure (sanitation level and health programs) makes PG a suitable habitat for the persistence and growth of a parasite metapopulation. We quantify the risk of SM metapopulation explosion and quasi‐extinction and the time to metapopulation explosion and quasi‐extinction. We evaluate the sensitivity of the results under varying scenarios of future periodic PZQ treatment (based on the Brazilian Ministry of Health's plan) and sanitation quality. We conclude that the plan might be useful to slow SM metapopulation growth but not to control it. Additional investments in better sanitation are necessary. 相似文献
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We introduce a new approach to hospital-acquired disease risk assessment from public health databases. In a spirit similar to actuarial risk theory, we define an adjustment coefficient that can quantify the risk associated with a hospital department, allowing comparisons of similar departments. The adjustment coefficient characterizes the tail of the distribution of the total patient length of stay in a department before the first disease event occurs. We show that this coefficient is the solution of a Lundberg-like equation, and we provide a nonparametric estimation procedure for this measure, based on a Cramér-Lundberg approximation for the tail of the distribution. Using simulations, we provide evidence of the robustness of the approximation to various individual risk models. In addition, we illustrate the relevance of this approach by evaluating the risk associated with a standard patient safety indicator in 20 hospitals of southeastern France. 相似文献
14.
François Portier 《Scandinavian Journal of Statistics》2016,43(3):827-844
A common approach taken in high‐dimensional regression analysis is sliced inverse regression, which separates the range of the response variable into non‐overlapping regions, called ‘slices’. Asymptotic results are usually shown assuming that the slices are fixed, while in practice, estimators are computed with random slices containing the same number of observations. Based on empirical process theory, we present a unified theoretical framework to study these techniques, and revisit popular inverse regression estimators. Furthermore, we introduce a bootstrap methodology that reproduces the laws of Cramér–von Mises test statistics of interest to model dimension, effects of specified covariates and whether or not a sliced inverse regression estimator is appropriate. Finally, we investigate the accuracy of different bootstrap procedures by means of simulations. 相似文献
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The aim of this study is to compare performances of commonly cointegration tests used in literature in terms of their empirical power and type I error probabilty for various sample sizes. As a result of the study, it has been found that some tests are not appropriate in testing cointegration in terms of empirical power and type I error probability. As a result of simulation study, λmax test for any values of ρ and sample sizes have been found most appropriate test in conclusion. 相似文献
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The binary logistic regression is a widely used statistical method when the dependent variable has two categories. In most of the situations of logistic regression, independent variables are collinear which is called the multicollinearity problem. It is known that multicollinearity affects the variance of maximum likelihood estimator (MLE) negatively. Therefore, this article introduces new shrinkage parameters for the Liu-type estimators in the Liu (2003) in the logistic regression model defined by Huang (2012) in order to decrease the variance and overcome the problem of multicollinearity. A Monte Carlo study is designed to show the goodness of the proposed estimators over MLE in the sense of mean squared error (MSE) and mean absolute error (MAE). Moreover, a real data case is given to demonstrate the advantages of the new shrinkage parameters. 相似文献
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AStA Advances in Statistical Analysis - In this paper, multivariate partially linear model with error in the explanatory variable of nonparametric part, where the response variable is m... 相似文献
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Gül Seçkidotn 《Journal of Technology in Human Services》2013,31(2):79-92
Internet technology has become an informational resource for most health care consumers. Online information, discussion, and support groups, in the form of message boards, listservs, and chat rooms are emerging as parts of virtual self-health-care network. This paper examines the extent to which participation in online health discussion groups was reported to be helpful in increasing medical knowledge and in enhancing the participatory patient role of health care consumers in interaction with health care service professionals. Data for this study was collected from 350 patients who participated in Internet discussion groups for cancer patients. The findings of the study indicated the important impact of Internet health discussion groups on health care management practices as perceived by health care consumers, including empowerment through knowledge and proactive participation in cancer care management. This research contributes to understanding the patient perspective and assesses the perceived importance of Internet groups by health care consumers. 相似文献
19.
Judite Leite Hugo S. Gomes Andreia de Castro-Rodrigues Rui Abrunhosa Gonçalves 《Journal of Child Custody》2018,15(2):116-135
In Portugal, there is a gap regarding psychological tests validated for forensic contexts, particularly those related to child custody issues. The Parent–Child Relationship Inventory (PCRI) is one of the most used instruments in child custody contexts. This study aimed to analyze the psychometric properties of PCRI in a Portuguese forensic sample. PCRI factorial structure and psychometric properties were analyzed in a sample of 144 parents involved in child custody assessments. The questionnaire showed good internal consistency, except for the parental support, autonomy, and role orientation scales. It also showed good discriminant capacity. The confirmatory factor analysis did not replicate the 7-factor model proposed by Gerard. The results were discussed based on the use of PCRI in the context of child custody assessment. 相似文献
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