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31.
This paper describes the use and evaluation of application cards as a teaching tool designed to enhance students' abilities to apply knowledge learned in social work practice classes. Strengths and limitations of this tool as a means for enhancing students' application skills are discussed, based on qualitative and quantitative evaluative data. 相似文献
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This study develops dose–response models for Ebolavirus using previously published data sets from the open literature. Two such articles were identified in which three different species of nonhuman primates were challenged by aerosolized Ebolavirus in order to study pathology and clinical disease progression. Dose groups were combined and pooled across each study in order to facilitate modeling. The endpoint of each experiment was death. The exponential and exact beta-Poisson models were fit to the data using maximum likelihood estimation. The exact beta-Poisson was deemed the recommended model because it more closely approximated the probability of response at low doses though both models provided a good fit. Although transmission is generally considered to be dominated by person-to-person contact, aerosolization is a possible route of exposure. If possible, this route of exposure could be particularly concerning for persons in occupational roles managing contaminated liquid wastes from patients being treated for Ebola infection and the wastewater community responsible for disinfection. Therefore, this study produces a necessary mathematical relationship between exposure dose and risk of death for the inhalation route of exposure that can support quantitative microbial risk assessment aimed at informing risk mitigation strategies including personal protection policies against occupational exposures. 相似文献
34.
Martin R. Owen Mark Armitage Marion Chatfield Bryan Davies David Emiabata‐Smith Steve Freeman Doug Hayes Inderjit Mann Tom Ramsay Linden Smith Barney Squires 《Pharmaceutical statistics》2003,2(1):15-29
This paper tackles the practical application of statistical tools. Chemical development is a rich area for collaboration between statisticians and chemists, but most statisticians encounter difficulties in promoting the tools to this client group. This paper, presented from a chemist's perspective, is intended to help bridge the gap between the two professions. The paper explores differences in uptake and attitudes towards adopting these techniques and suggests what has hindered or helped the process of effective application of experimental design. Copyright © 2003 John Wiley & Sons, Ltd. 相似文献
35.
In this paper, we focus on models for recovery data from birds ringed as young. In some cases, it is important to be able to include in these models a degree of age variation in the reporting probability. For certain models this has been found, empirically, to result in completely flat likelihood surfaces, due to parameter redundancy. These models cannot then be fitted to the data, to produce unique parameter estimates. However, empirical evidence also exists that other models with such age variation can be fitted to data by maximum likelihood. Using the approach of Catchpole and Morgan (1996b), we can now identify which models in this area are parameter-redundant, and which are not. Models which are not parameter-redundant may still perform poorly in practice, and this is investigated through examples, involving both real and simulated data. The Akaike Information Criterion is found to select inappropriate models in a number of instances. The paper ends with guidelines for fitting models to data from birds ringed as young, when age dependence is expected in the reporting probability. 相似文献
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Freeman EM 《Journal of social work & human sexuality》1989,8(1):113-131
Reductions in the number of adolescent pregnancies in the US demand greater recognition of the role of adolescent males, especially in urban environments, and their developmental needs. With its person-in- environment orientation, the social work profession is in a strong position to ameliorate this gap in services. Key developmental issues for teenage males include "hanging out" with peers in networks that communicate information about social behaviors such as premarital sex, separation from one's parents, securing employment so that there can be financial independence, courtship and the consolidation of a male (e.g., macho) image, and identity formation. Since the resources necessary for positive identity formation are frequently unavailable in poor urban centers, impregnating an adolescent female may become an alternative source of self-esteem. Social workers should, with the assistance of the target population, carry out an assessment of all resources available in a given community to meet the developmental needs of adolescent males, identify significant gaps, determine the extent to which available resources are being used appropriately and develop strategies--in collaboration with young males--to provide access to existing resources or create new ones. A community forum framework has been most effective as a launching vehicle for pregnancy prevention programs. 相似文献
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The United Nations Convention on the Rights of the Child requires that children ‘have the right to be heard in matters affecting them’ (Article 12). Given that planning matters such as housing, transport, services and recreation provision affect children, it is necessary, therefore, for planners to engage with children. While planning has made considerable progress in working with older children, preschool children have been overlooked. Preschoolers are commonly seen as lacking the understanding necessary to comprehend the city scale. This paper presents a tile-based city-mapping method that demonstrates preschool children do understand city-scale features and relationships. Further, this method could be used in planning to advocate for and to engage with very young children in planning conversations. 相似文献
40.
A Meta-Analysis of Children's Hand-to-Mouth Frequency Data for Estimating Nondietary Ingestion Exposure 总被引:1,自引:0,他引:1
Jianping Xue Valerie Zartarian Jacqueline Moya Natalie Freeman Paloma Beamer Kathy Black Nicolle Tulve Stuart Shalat 《Risk analysis》2007,27(2):411-420
Because of their mouthing behaviors, children have a higher potential for exposure to available chemicals through the nondietary ingestion route; thus, frequency of hand-to-mouth activity is an important variable for exposure assessments. Such data are limited and difficult to collect. Few published studies report such information, and the studies that have been conducted used different data collection approaches (e.g., videography versus real-time observation), data analysis and reporting methods, ages of children, locations, and even definitions of "mouthing." For this article, hand-to-mouth frequency data were gathered from 9 available studies representing 429 subjects and more than 2,000 hours of behavior observation. A meta-analysis was conducted to study differences in hand-to-mouth frequency based on study, age group, gender, and location (indoor vs. outdoor), to fit variability and uncertainty distributions that can be used in probabilistic exposure assessments, and to identify any data gaps. Results of this analysis indicate that age and location are important for hand-to-mouth frequency, but study and gender are not. As age increases, both indoor and outdoor hand-to-mouth frequencies decrease. Hand-to-mouth behavior is significantly greater indoors than outdoors. For both indoor and outdoor hand-to-mouth frequencies, interpersonal, and intra-personal variability are approximately 60% and approximately 30%, respectively. The variance difference among different studies is much bigger than its mean, indicating that different studies with different methodologies have similar central values. Weibull distributions best fit the observed data for the different variables considered and are presented in this article by study, age group, and location. Average indoor hand-to-mouth behavior ranged from 6.7 to 28.0 contacts/hour, with the lowest value corresponding to the 6 to <11 year olds and the highest value corresponding to the 3 to <6 month olds. Average outdoor hand-to-mouth frequency ranged from 2.9 to 14.5 contacts/hour, with the lowest value corresponding to the 6 to <11 year olds and the highest value corresponding to the 6 to <12 month olds. The analysis highlights the need for additional hand-to-mouth data for the <3 months, 3 to <6 months, and 3 to <6 year age groups using standardized collection and analysis because of lack of data or high uncertainty in available data. This is the first publication to report Weibull distributions as the best fitting distribution for hand-to-mouth frequency; using the best fitting exposure factor distribution will help improve estimates of exposure. The analyses also represent a first comprehensive effort to fit hand-to-mouth frequency variability and uncertainty distributions by indoor/outdoor location and by age groups, using the new standard set of age groups recommended by the U.S. Environmental Protection Agency for assessing childhood exposures. Thus, the data presented in this article can be used to update the U.S. EPA's Child-Specific Exposure Factors Handbook and to improve estimates of nondietary ingestion in probabilistic exposure modeling. 相似文献