Memorable encounters: Ideology,information acquisition,and television news

Many consumers of television news perceive the ideological position held by certain networks as being either consonant with, or dissonant from, their own political beliefs. This raises the question of how the perceived consonance or dissonance of media sources influences the viewer's ability to acquire and recall information. It is possible that being exposed to a consonant media source could lead an individual to pay more attention, whereas the individual would be more inclined to dismiss a dissonant media source. In contrast, however, it is also possible that an individual may pay extra attention to the dissonant media source because it presents a perspective that differs from the one that individual currently holds. Utilizing an experimental research design, I am able to demonstrate that individuals are better able to acquire and recall information presented to them by a media source that they perceive to be ideologically dissonant from their own political position.     

Ordinary Least Squares and Sample-Selection Models of Health-Care Demand Monte Carlo Comparison

This article examines alternative econometric models for health-care demand estimation. The analysis compares the Rand Health Insurance Study two-part model with sample-selection model estimators in a Monte Carlo simulation experiment designed to approximate individual-level health-care demand conditions. The underlying variable distributions are taken from cross- sectional data for a Swiss 1981 population survey. Three sets of error distribution assumptions are examined—bivariate normal, normal logistic, and Cauchy. Despite theoretical concerns with the two-part model, it outperforms the sample-selection model in terms of mean squared error of parameter estimate.     

The Politics of Space and Culture in Santiago, Chile’s Street Markets

Recent discussions of contentious politics have focused on struggles in and over space and place. This article builds upon these concerns by using ethnographic, interview, and documentary data to analyze the spatial politics of street market vendors in Santiago, Chile. Drawing upon Lefebvre’s concepts of perceived, conceived, and lived space as well as ideas drawn from research on space and protest, I show how street market vendors build upon spatial routines, a sense of place, political alliances, and scale jumping in their self-defense strategies at the local, national, and international scales. The findings illustrate Lefebvre’s argument that the advance of abstract space (constructed by dominant economic and political elites) provokes resistance by groups who defend and seek to reconstruct lived space.

Mechanistic Insights Aid the Search for CFC Substitutes: Risk Assessment of HCFC-123 as an Example

An international consensus on the need to reduce the use of chlorofluorocarbons (CFCs) and other ozone-depleting gases such as the halons led to the adoptions of the 1987 Montreal Protocol and Title VI of the 1990 Clean Air Act Amendments, "Protecting Stratospheric Ozone." These agreements included major provisions for reducing and eventually phasing out production and use of CFCs and halons as well as advancing the development of replacement chemicals. Because of the ubiquitous use and benefits of CFCs and halons, an expeditious search for safe replacements to meet the legislative deadlines is of critical importance. Toxicity testing and health risk assessment programs were established to evaluate the health and environmental impact of these replacement chemicals. Development and implementation of these programs as well as the structural-activity relationships significant for the development of the replacement chemicals are described below. A dose-response evaluation for the health risk assessment of the replacement chemical HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) is also presented to show an innovative use of physiologically based pharmacokinetic (PBPK) modeling. This is based on a parallelogram approach using data on the anesthetic gas halothane, a structural analog to HCFC-123. Halothane and HCFC-123 both form the same metabolite, trifluoroacetic acid (TFA), indicative of the same metabolic oxidative pathway attributed to hepatotoxicity. The parallelogram approach demonstrates the application of template model structures and shows how PBPK modeling, together with judicious experimental design, can be used to improve the accuracy of health risk assessment and to decrease the need for extensive laboratory animal testing.     

The Durham Family Initiative: a preventive system of care

This article describes the Durham Family Initiative (DFI), an innovative effort to bring together child welfare and juvenile justice systems to reach DFI's goal of reducing the child abuse rate in Durham, North Carolina, by 50% within the next 10 years. DFI will follow principles of a preventive system of care (PSoC), which focuses on nurturing the healthy parent-child relationship. A community collaborative of government agency directors has signed a memorandum of agreement to implement the PSoC principles. The researchers will use multiple methods to evaluate DFI's efficacy.     

The Doubles: a case study on developing a technology-based substance abuse education curriculum

The Doubles, funded by the National Institute on Drug Abuse, is a seven-episode series of media tools designed to teach third and fourth grade students about the science of drug addiction. The program's curriculum is delivered via a set of videos, interactive CD-ROMs, workbooks, or an Internet site. This article examines the process used to develop The Doubles and argues that its success stems from the careful balancing of the needs of the funding agency, state and national curricular guidelines, and the target audience.