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201.
    
Risk assessments are crucial for identifying and mitigating impacts from biological invasions. The Fish Invasiveness Scoring Kit (FISK) is a risk identification (screening) tool for freshwater fishes consisting of two subject areas: biogeography/history and biology/ecology. According to the outcomes, species can be classified under particular risk categories. The aim of this study was to apply FISK to the Iberian Peninsula, a Mediterranean climate region highly important for freshwater fish conservation due to a high level of endemism. In total, 89 fish species were assessed by three independent assessors. Results from receiver operating characteristic analysis showed that FISK can discriminate reliably between noninvasive and invasive fishes for Iberia, with a threshold of 20.25, similar to those obtained in several regions around the world. Based on mean scores, no species was categorized as “low risk,” 50 species as “medium risk,” 17 as “moderately high risk,” 11 as “high risk,” and 11 as “very high risk.” The highest scoring species was goldfish Carassius auratus. Mean certainty in response was above the category “mostly certain,” ranging from tinfoil barb Barbonymus schwanenfeldii with the lowest certainty to eastern mosquitofish Gambusia holbrooki with the highest level. Pair‐wise comparison showed significant differences between one assessor and the other two on mean certainty, with these two assessors showing a high coincidence rate for the species categorization. Overall, the results suggest that FISK is a useful and viable tool for assessing risks posed by non‐native fish in the Iberian Peninsula and contributes to a “watch list” in this region.  相似文献   
202.
    
This study investigates how lot sizing techniques influence the profit performance, inventory level, and order lardiness of an assembly job shop controlled by MRP. Four single-level lot sizing techniques are compared by simulation analysis under two levels of master schedule instability and two levels of end item demand. A second analysis investigates the influence of a multilevel lot sizing technique, the generalized constrained-K (GCK) cost modification, on the four single-level techniques at low demand and low nervousness. The analyses reveal a previously unreported phenomenon. Given the same inventory costs, the single-level lot sizing techniques generate substantially different average batch sizes. The lot sizing techniques maintain the following order of increasing average batch size (and decreasing total setup time):

economic order quantity (EOQ)

period order quantity (POQ)

least total cost (LTC)

Silver-Meal heuristic (SML)

The causes for different average batch sizes among the lot sizing techniques are analysed and explained. Demand lumpiness, inherent in multilevel manufacturing systems controlled by MRP, is found to be a major factor. The number of setups each lot sizing technique generates is the primary determinant of profit performance, inventory level, and order tardiness. EOQ, a fixed order quantity technique, is less sensitive to nervousness than the discrete lot sizing techniques. EOQ_, however, generates the smallest average batch size, and, therefore, the most setups. Since setups consume capacity, EOQ, is more sensitive to higher demand. SML generates the largest average batch sizes, and is, therefore, less sensitive to increased demand. At low demand, the other lot sizing techniques perform better on all criteria. They generate smaller batches and, therefore, shorter actual lead times. The GCK cost modification increases the average batch size generated by each lot sizing technique. GCK improves the profit and customer service level of EOQ the lot sizing technique with the smallest batches. GCK causes the other lot sizing techniques to generate excessively large batches and, therefore, excessively long actual lead times.  相似文献   
203.
    
Gordon H. Copp 《Risk analysis》2013,33(8):1394-1396
  相似文献   
204.
    
Today's manufacturing enterprises face tremendous competitive pressures. Global competition, together with market demands for customized products delivered just in time, place tremendous pressures on manufacturers. The emerging global economy is rapidly replacing local markets. The emergence of open markets, reductions in trade barriers, and improvements in transportation and communications links have led to a situation where local competition and markets operate in the context of global standards. This open infrastructure allows manufacturers to respond to these challenges by working more closely with their suppliers and customers, and by building extended enterprises across the whole value chain. Such extended enterprises present great challenges in terms of redesigning business processes to create a competitive advantage from the linkages they include. This paper describes the manufacturing philosophies currently in vogue. Any manufacturing or related business will need to use them, albeit tailored to its own circumstances, in one form or the other, to ensure its prosperity.  相似文献   
205.
    
One of the basic functions of an MRP system is to issue rescheduling messages that urge the planner tospeed up or slow down open orders. It seems in practice that these messages are not used at all by planners. This is mostly due to the inaccuracy of MRP, that more or less ignores safety time, safety stocks and lotsize flexibility in the calculation of reschedule-in messages. Reschedule-out messages are usually ignored because planners do not see the value of the message. Other reasons for not adhering to rescheduling messages are a lack of maintenance of MRP parameters or simply the wrong use of the MRP function. In the future, MRP rescheduling functionality will be used even less than today, due to the changing role of MRP within the planning framework. With the uprise of finite capacity scheduling packages, MRP is being pushed one level upward in the planning hierarchy. This means that rescheduling functionalities for the short term will become completely obsolete in MRP systems.  相似文献   
206.
    

DEWIP is a manufacturing control system for job shop environments aiming at achieving short and reliable lead times by establishing WIP control loops between the manufacturing work centres. The paper describes the mode of function, the setting of parameters and simulation results of the new manufacturing control system. The setting of parameters is done with the aid of the funnel model and the theory of logistic operating curves, both developed at the Institute of Production Systems at the University of Hanover. The simulation is conducted using industrial data and makes it possible to assess DEWIP with regard to lead times, WIP level, performance and schedule reliability. DEWIP is compared both with an uncontrolled process and with the manufacturing control systems Load oriented order release (LOOR), Conwip and Polca. The results suggest that DEWIP and the models employed for the setting of parameters are suitable for job shop production and therefore offer a valuable alternative to prevailing centralized manufacturing control systems.  相似文献   
207.
Reverse logistics is considered to be the key for re-manufacturing and sustainable development. It has gained increasing attention in the last decade and has been a new frontier of strategic management. One of the driving forces for firms to adopt the reverse logistics practice is cost saving from reverse logistics activities. Another motivation to put reverse logistics forward is probably due to environmental impacts on non-returnable materials. Reverse logistics, however, may require cooperation of more than one company and hence it is generally poorly managed due to self-interest of different companies. Therefore, a pro-active and collaborative approach to reverse logistics is demanded. This paper reports a case study of using returnable packaging materials between a manufacturer and an original equipment manufacturer (OEM) supplier. A cross-company team was established to pursue the goal of the reverse logistics project. Tangible and intangible benefits of reverse logistics from this case study are presented in this paper.  相似文献   
208.
    
Processes of serially dependent Poisson counts are commonly observed in real-world applications and can often be modeled by the first-order integer-valued autoregressive (INAR) model. For detecting positive shifts in the mean of a Poisson INAR(1) process, we propose the one-sided s exponentially weighted moving average (EWMA) control chart, which is based on a new type of rounding operation. The s-EWMA chart allows computing average run length (ARLs) exactly and efficiently with a Markov chain approach. Using an implementation of this procedure for ARL computation, the s-EWMA chart is easily designed, which is demonstrated with a real-data example. Based on an extensive study of ARLs, the out-of-control performance of the chart is analyzed and compared with that of a c chart and a one-sided cumulative sum (CUSUM) chart. We also investigate the robustness of the chart against departures from the assumed Poisson marginal distribution.  相似文献   
209.
    
The use of surrogate variables has been proposed as a means to capture, for a given observed set of data, sources driving the dependency structure among high-dimensional sets of features and remove the effects of those sources and their potential negative impact on simultaneous inference. In this article we illustrate the potential effects of latent variables on testing dependence and the resulting impact on multiple inference, we briefly review the method of surrogate variable analysis proposed by Leek and Storey (PNAS 2008; 105:18718-18723), and assess that method via simulations intended to mimic the complexity of feature dependence observed in real-world microarray data. The method is also assessed via application to a recent Merck microarray data set. Both simulation and case study results indicate that surrogate variable analysis can offer a viable strategy for tackling the multiple testing dependence problem when the features follow a potentially complex correlation structure, yielding improvements in the variability of false positive rates and increases in power.  相似文献   
210.
    
This continuing education course for professionals involved in all areas of clinical trials integrates concepts related to the role of randomization in the scientific process. The course includes two interactive lecture and discussion sections and a workshop practicum. The first interactive lecture introduces basic clinical trial issues and statistical principles such as bias, blinding, randomization, control groups, and the importance of formulating clear and discriminating clinical and statistical hypotheses. It then focuses on the most commonly used clinical study designs and the corresponding patient randomization schemes. The second interactive lecture focuses on the implementation of randomization of patients and drug supply through allocation and component ID schedules. The workshop practicum, conducted in small groups, enables students to apply the lecture concepts to real clinical studies. Flexibility was built into the workshop practicum materials to allow the course content to be customized to specific audiences, and the interactive lecture sessions can be stretched to cover more advanced topics according to class interest and time availability.  相似文献   
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