Differential Item Functioning of Pathological Gambling Criteria: An Examination of Gender, Race/Ethnicity, and Age

This study tested for the presence of differential item functioning (DIF) in DSM-IV Pathological Gambling Disorder (PGD) criteria based on gender, race/ethnicity and age. Using a nationally representative sample of adults from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), indicating current gambling (n = 10,899), Multiple Indicator-Multiple Cause (MIMIC) models tested for DIF, controlling for income, education, and marital status. Compared to the reference groups (i.e., Male, Caucasian, and ages 25–59 years), women (OR = 0.62; P < .001) and Asian Americans (OR = 0.33; P < .001) were less likely to endorse preoccupation (Criterion 1). Women were more likely to endorse gambling to escape (Criterion 5) (OR = 2.22; P < .001) but young adults (OR = 0.62; P < .05) were less likely to endorse it. African Americans (OR = 2.50; P < .001) and Hispanics were more likely to endorse trying to cut back (Criterion 3) (OR = 2.01; P < .01). African Americans were more likely to endorse the suffering losses (OR = 2.27; P < .01) criterion. Young adults were more likely to endorse chasing losses (Criterion 9) (OR = 1.81; P < .01) while older adults were less likely to endorse this criterion (OR = 0.76; P < .05). Further research is needed to identify factors contributing to DIF, address criteria level bias, and examine differential test functioning.     

Mapping the Field of Donation-Based Crowdfunding for Charitable Causes: Systematic Review and Conceptual Framework

VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations - This study compiles the main findings in the field of academic research on pure donation-based crowdfunding (DCF)...     

Incorporating Struggles with Racism and Ethnic Identity in Therapy with Adolescents

Ethnic and racial minority adolescents enter therapy with the behavioral, emotional, social, familial, and educational problems common to clinical practice. However, therapy with these youth necessitates attention to the effects of racial discrimination on their psychological functioning and to matters of how their ethnic or racial identities are integrated. Of the myriad issues that become part of therapy with minority adolescents, the profound effects of racism and the process of ethnoracial identity development can be seen in adolescents' sense of self and behavior. Experiences with racism and with their own ethnic reference group and others may have led to distortions and partial understanding of their identities that may affect adaptation and functioning. In this paper, the author draws from experiences in clinical practice with minority youth to highlight issues of racism and ethnic identity emergent in treatment. Three cases illustrate discussions of struggles with racism and ethnic identity as they emerged in therapy. In each case, the struggles were made salient by the therapist's purposeful eliciting of them to clarify issues of transference, family relations, peer group relations, and achievement.     

Childrearing,social stress,and child abuse: Clinical considerations with Hispanic families

Child abuse in our multicultural society is a national emergency. As a nation, our approach to managing this societal crisis has been one of indifference to cultural variations among families and children, under the prevailing belief that cultural diversity does not play a part when serving a single society. Experience, however, shows that consideration of ethnocultural factors is warranted if we are to effectively treat and prevent child maltreatment. In this paper, a sociocultural perspective on child maltreatment in the United States Hispanic population is presented. Social stresses experienced by Hispanics along a continuum from emigration and migration, to arrival and adjustment to a new culture, and to the sociocultural and economic conditions they face in the United States are linked to factors of individual psychology. Traditional childrearing values and practices and factors of assessment and intervention are discussed with an emphasis on the changing characteristics of Hispanics.     

Body mass index and functional status in community dwelling older Turkish males

Abstract

Objectives: To assess sex hormones in men with obesity and prostate cancer (PCa) and to study association between androgens and the pathogenesis biology of PCa in vitro.

Subjects and methods: One hundred and eighty-one men older than 45?years selected from of a population attending to Urology departments screening for PCa, (78 participants without PCa and 103 patients with PCa). All participants were assessed for body mass index (BMI), age, Gleason score, and PSA. Endocrine profile was determined for LH, total testosterone (TT), 17β-estradiol (E2), prolactin and leptin. Biochemical profile (HbA1c, triacylglycerols and lipoproteins) was also determined. In vitro experiments were also performed, involving the study of 5α-dihydrotestosterone (DHT) and E2 in the presence of adipocyte-conditioned medium (aCM).

Results: All variables were continuous and described a Gaussian distribution unless mentioned. To determine the relation of aggressiveness, variable were transformed into categories. Thus, PCa aggressiveness is associated with the increase of age and BMI (p?<?.0001) but with is decreased with TT and E2 (p?<?.05). Moreover, adipocyte-secreted molecules increase aggressiveness of PCa cells in vitro. Lastly, DTH but not E2 enables invasiveness in vitro.

Conclusions: It was observed a coexistence of hormone axis profile alteration with sex hormones and BMI in PCa patients, in accordance with the new perspective of PCa pathogenesis.     

Living with zombie companies: Do we know where the threat lies?

This paper shows the existence of extreme types of zombie firm, i.e. companies with negative equity that continue to do business despite having lost their entire equity. We explain how these firms are measured and how the riskier ones are defined with different determinants. Using a Spanish sample from 2010 to 2014 an index called the EZIndex is developed that includes four dimensions of the extreme zombie problem: extension, contagion, recovery signs and immediacy. The paper contributes to zombie theory on the one hand by developing a method for ranking zombie firms based on risks and changes over time, and on the other hand by using a log-linear model to detect the riskiest corporate profiles out of all these risky firms. It demonstrates significant implications that need to be considered by the competent authorities not only in terms of their impact as a whole but also in regard to the particular profile of extreme zombie firms: they are less regulated, large and located in regions with large business fabrics.     

Bayesian Random Segmentation Models to Identify Shared Copy Number Aberrations for Array CGH Data

Array-based comparative genomic hybridization (aCGH) is a high-resolution high-throughput technique for studying the genetic basis of cancer. The resulting data consists of log fluorescence ratios as a function of the genomic DNA location and provides a cytogenetic representation of the relative DNA copy number variation. Analysis of such data typically involves estimation of the underlying copy number state at each location and segmenting regions of DNA with similar copy number states. Most current methods proceed by modeling a single sample/array at a time, and thus fail to borrow strength across multiple samples to infer shared regions of copy number aberrations. We propose a hierarchical Bayesian random segmentation approach for modeling aCGH data that utilizes information across arrays from a common population to yield segments of shared copy number changes. These changes characterize the underlying population and allow us to compare different population aCGH profiles to assess which regions of the genome have differential alterations. Our method, referred to as BDSAcgh (Bayesian Detection of Shared Aberrations in aCGH), is based on a unified Bayesian hierarchical model that allows us to obtain probabilities of alteration states as well as probabilities of differential alteration that correspond to local false discovery rates. We evaluate the operating characteristics of our method via simulations and an application using a lung cancer aCGH data set.     

Hand-Hygiene Mitigation Strategies Against Global Disease Spreading through the Air Transportation Network

The risk for a global transmission of flu-type viruses is strengthened by the physical contact between humans and accelerated through individual mobility patterns. The Air Transportation System plays a critical role in such transmissions because it is responsible for fast and long-range human travel, while its building components—the airports—are crowded, confined areas with usually poor hygiene. Centers for Disease Control and Prevention (CDC) and World Health Organization (WHO) consider hand hygiene as the most efficient and cost-effective way to limit disease propagation. Results from clinical studies reveal the effect of hand washing on individual transmissibility of infectious diseases. However, its potential as a mitigation strategy against the global risk for a pandemic has not been fully explored. Here, we use epidemiological modeling and data-driven simulations to elucidate the role of individual engagement with hand hygiene inside airports in conjunction with human travel on the global spread of epidemics. We find that, by increasing travelers engagement with hand hygiene at all airports, a potential pandemic can be inhibited by 24% to 69%. In addition, we identify 10 airports at the core of a cost-optimal deployment of the hand-washing mitigation strategy. Increasing hand-washing rate at only those 10 influential locations, the risk of a pandemic could potentially drop by up to 37%. Our results provide evidence for the effectiveness of hand hygiene in airports on the global spread of infections that could shape the way public-health policy is implemented with respect to the overall objective of mitigating potential population health crises.     

Constructing 1-rotational NRDFs through an optimization approach: new (46,9,8), (51,10,9) and (55,9,8)-NRBDs

In this paper we formulate the problem of constructing 1-rotational near resolvable difference families as a combinatorial optimization problem where a global optimum corresponds to a desired difference family. Then, we develop an algorithm based on scatter search in conjunction with a tabu search to construct many of these difference families. In particular, we construct three new near resolvable difference families which lead to an equal number of new 1-rotational near resolvable block designs with parameters: (46,9,8), (51,10,9) and (55,9,8). Our results indicate that this conjunction outperforms both scatter search and tabu search.