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Treating male lower urinary tract symptoms (LUTS) by targeting the prostate would have limited effect on overactive bladder (OAB) symptoms. This study assessed perceived symptoms and quality of life (QoL) of male patients with OAB treated with an α-blocker plus solifenacin in daily clinical practice. Male patients aged ≥40 years were included after the decision was made to initiate treatment with an α-blocker for LUTS plus solifenacin for OAB symptoms. The primary endpoint was change in patient perception of bladder condition (PPBC) questionnaire score over 6?months. Other assessments included the OAB-questionnaire short form (OAB-q SF) and International Prostate Symptom Score (IPSS). Interpretation of the study data was hindered by not meeting the enrollment target and a high dropout rate. In 36 evaluable patients, mean (SD) PPBC score improved from 4.3 (0.93) at baseline (“moderate” to “severe” problems) to 3.5 (1.06) at month 6 (“minor” to “moderate” problems). OAB-q SF scores and total IPSS also improved. In this patient population, treatment with solifenacin and an α-blocker resulted in improvements in male patient perception of their LUTS and QoL, although the results should be interpreted with caution due to the low number of patients with complete data. 相似文献
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Maja Cederberg 《Journal of ethnic and migration studies》2019,45(1):115-132
The literature on ethnic entrepreneurship has focused on structural factors, group characteristics or a combination of both when explaining the entry and/or success of different ethnic groups in/to self-employment. While the active involvement of individuals has often been noted, agency has been under-theorised, and frequently conflated with what are considered as ‘cultural’ factors. This article explores the question of agency in ethnic entrepreneurship by looking at how entrepreneurs access and mobilise different kinds of resources. Using a forms-of-capital approach, the article draws on qualitative data from the U.K. and Spain, and looks at how entrepreneurs mobilise cultural, social and economic resources in structural contexts that include constraining as well as enabling features. Our findings show that the entrepreneurs are active agents who play an important role in shaping ethnic businesses. However, their agency varies significantly depending on the extent to which entrepreneurs have access to different kinds of resources, which is closely linked to their socioeconomic position. The article contributes to the literature through its direct engagement with the question of agency in ethnic entrepreneurship, and by highlighting the relevance of social class in entrepreneurial processes. 相似文献
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Marjolein Verhoeven Marianne Junger Chantal
Van Aken Maja Deković Marcel A. G.
Van Aken 《Journal of marriage and the family》2010,72(2):307-317
This study examined the effects of reported maternal and paternal support, psychological control, and spanking on externalizing behavior of toddler boys. Questionnaires were administered to both parents of 104 two‐parent families with a 3‐year‐old son. Both maternal and paternal psychological control was related to boys' externalizing behavior. Interaction effects were found, in that the association between maternal spanking and boys' externalizing behavior was stronger when levels of maternal support were high. High levels of paternal support strengthened the association between maternal support and boys' externalizing behaviors. Results suggest that the associations between specific parenting dimensions and children's externalizing behavior need to be considered within the context of other parenting dimensions that are displayed within the family. 相似文献
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Jo M.A. Hermanns Jessica J. Asscher Bonne J.H. Zijlstra Peter J. Hoffenaar Maja Dekovič 《Children and youth services review》2013