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101.
Borroi Mario Minoja Mario Sinatra Alessandro 《Journal of Management and Governance》1998,2(3):233-266
This paper discusses the relationship between the subjective organisation and the perceived competitive structure of an industry based on an empirical study of the Carpi textile-clothing district, which partially replicates a previous study of the Scottish knitwear industry conducted by other authors (Porac et al., 1995). The initial hypothesis to be tested is that an industry may be broken down into a number of subsets of firms within which competition is perceived as being fiercer as compared with firms in different subsets. These subsets, or groups, correspond to the groups or types of firms into which decision-makers -- managers and entrepreneurial business owners alike -- perceive the industry as being divided.The results of the study are then compared to the empirical evidence from the research conducted by other authors. This comparison provides some interesting elements for investigating the relationships between industry complexity, cognitive maps and strategies implemented by the firms belonging to it. After suggesting a definition of complexity of an industry as the number of strategies implemented in it by competitors, we discuss the hypothesis that key-actors in the firms develop a mental picture of their environment that tends to become less comprehensive and accurate as the degree of complexity of the environment itself increases. 相似文献
102.
J. Andrés Christen Bruno Sansó Mario Santana-Cibrian Jorge X. Velasco-Hernández 《Journal of applied statistics》2016,43(4):721-737
We use Bayesian methods to infer an unobserved function that is convolved with a known kernel. Our method is based on the assumption that the function of interest is a Gaussian process and, assuming a particular correlation structure, the resulting convolution is also a Gaussian process. This fact is used to obtain inferences regarding the unobserved process, effectively providing a deconvolution method. We apply the methodology to the problem of estimating the parameters of an oil reservoir from well-test pressure data. Here, the unknown process describes the structure of the well. Applications to data from Mexican oil wells show very accurate results. 相似文献
103.
Mario Nagase Shinya Ueda Mitsuo Higashimori Katsuomi Ichikawa James Dunyak Nidal Al‐Huniti 《Pharmaceutical statistics》2020,19(1):22-30
As described in the ICH E5 guidelines, a bridging study is an additional study executed in a new geographical region or subpopulation to link or “build a bridge” from global clinical trial outcomes to the new region. The regulatory and scientific goals of a bridging study is to evaluate potential subpopulation differences while minimizing duplication of studies and meeting unmet medical needs expeditiously. Use of historical data (borrowing) from global studies is an attractive approach to meet these conflicting goals. Here, we propose a practical and relevant approach to guide the optimal borrowing rate (percent of subjects in earlier studies) and the number of subjects in the new regional bridging study. We address the limitations in global/regional exchangeability through use of a Bayesian power prior method and then optimize bridging study design with a return on investment viewpoint. The method is demonstrated using clinical data from global and Japanese trials in dapagliflozin for type 2 diabetes. 相似文献
104.
In dose-response models, there are cases where only a portion of the administered dose may have an effect. This results in a stochastic compliance of the administered dose. In a previous paper (Chen-Mok and Sen, 1999), we developed suitable adjustments for compliance in the logistic model under the assumption of nondifferential measurement error. These compliance-adjusted models were categorized into three types: (i) Low (or near zero) dose levels, (ii) moderate dose levels, and (iii) high dose levels. In this paper, we analyze a set of data on the atomic bomb survivors of Japan to illustrate the use of the proposed methods. In addition, we examine the performance of these methods under different conditions based on a simulation study. Among all three cases, the adjustments proposed for the moderate dose case do not seem to work adequately. Both bias and variance are larger when using the adjusted model in comparison with the unadjusted model. The adjustments for the low dose case seem to work in reducing the bias in the estimation of the parameters under all types of compliance distributions. The MSEs, however, are larger under some of the compliance distribution considered. Finally, the results of this simulation study show that the adjustments for the high dose case are successful in achieving both a reduction in bias as well as a reduction in MSE, hence the overall efficiency of the estimation is improved. 相似文献
105.
Alberto J. Alaniz Jorge G. Carvajal Mario A. Carvajal Massimo Cogliati Pablo M. Vergara 《Risk analysis》2020,40(3):524-533
Cryptococcus is an important fungal pathogen worldwide, causing serious clinical manifestations that can affect immunocompetent patients and can be particularly severe for immunocompromised patients. The Cryptococcus gattii s.s. (AFLP4/VGI), Cryptococcus tetragattii (AFLP/VGIV), Cryptococcus neoformans, and Cryptococcus deneoformans have been isolated from both clinical and environmental sources in Europe. We aim to quantify the people in Europe and the entire Mediterranean area who are under risk associated with each of the three fungal pathogens in a spatially explicit way, generating a series of maps and population statistics per country. Niche modeling was applied to estimate the potential distribution of each fungal pathogen, then these models were overlapped with a map of population density to estimate risk levels. The potential number of people per risk level and per country was quantified using a map of population count per pixel. Prevalence of HIV per country was also included in the analysis to quantify the HIV-infected population under potential risk. People under risk associated with exposure to C. gattii species (C. gattii s.s. and C. tetragattii) reached 137.65 million, whereas those exposed to C. neoformans and C. deneoformans were 268.58 and 360.78 million people, respectively. More than a half million HIV-infected patients are exposed to each of the two species of the C. neoformans species complex, and more than 200,000 to the C. gattii species complex. The present results can be useful for public health planning by European governments, focusing on the provision of inputs for a “screen-and-treat” approach, availability of medical resources, and continuous monitoring programs in risk zones. 相似文献
106.
In this article we investigate how human and social capital contribute to individual productivity. We study three firms that complete all their tasks as projects. The employees in all firms initiate and organise their projects. We collected archival data from the firms on performance, human capital, tenure, gender and their project activities. Social network data are generated from interviews and a survey. We find that social capital is the most important factor to determine productivity. We found mixed effects from human capital; only in one firm did human capital have a noticeable effect on productivity; tenure has no effects on productivity. 相似文献
107.
The objective of this study was to ascertain whether a symposium on elder abuse raises the level of knowledge and the self-reported likelihood to report elder abuse among licensed oral health care providers. 130 dentists, hygienists, and assistants voluntarily attended a 4-hour training symposium and completed both pre- and postsurveys testing their level of knowledge. Results by statistical analyses, using repeated measurements, Wilcoxon signed-rank test for nonparametric data, showed increases in awareness of reporting process, knowledge/awareness of elder abuse, knowledge of mandated reporter requirements, and comfort levels with recognizing signs and symptoms of elder abuse and neglect. In conclusion, a symposium can increase the self-reported likelihood of reporting elder abuse. 相似文献
108.
Since the beginnings of time humans have searched for a fountain of youth. This has led to many extravagant claims which have been highly profitable for their proponents. This area has become known as anti-aging medicine and has deservedly been frowned upon by the medical establishment. On the other hand, in the last decades dramatic advances in our understanding of the aging process have come from studies in worms, flies and mice. This article reviews some of these advances and places the extravagant claims of anti-aging medicine in perspective. We conclude that a balanced diet of moderate proportions and exercise remain today the only proven fountain of youth. 相似文献
109.
Richard L. Beaulaurier Shelley L. Craig Mario De La Rosa 《Journal of gerontological social work》2013,56(1):48-63
Older Latina women are one of the least studied American demographic groups with regard to social, health, or sexual behavior. This could leave social workers and other geriatric professionals unprepared for dealing with HIV/AIDS in this population. Currently, older Latina women are one of the fastest growing groups of new AIDS cases. Twenty percent of all women ever diagnosed with the disease are Latina and 5.5% of Latinas infected with the virus are older. The number of diagnosed infections is increasing in older women, including Latinas, in spite of recent declines in infection rates with younger populations. There are also a potentially large number of cases that go misdiagnosed or undiagnosed. This article also addresses risk and protective factors related to gender roles, traditional Latino family values, religion, socioeconomic factors, health, and health care, with special attention to the triple jeopardy faced by this population by virtue of being female, seniors, and minorities. The article concludes with recommendations for the development of culturally competent practices with older Latinas and the development of a research agenda to better understand their risk-related and health-seeking behavior. 相似文献
110.
Lakner Christoph Mahler Daniel Gerszon Negre Mario Prydz Espen Beer 《Journal of Economic Inequality》2022,20(3):559-585
The Journal of Economic Inequality - The goals of ending extreme poverty by 2030 and working towards a more equal distribution of incomes are part of the United Nations’ Sustainable... 相似文献