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Statistics and Computing - 相似文献
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本文以详尽的历史事实为依据,对西方资本主义国家中的紧急状态及所谓的法治进行了深入的研究与批评,以此为基础,对西方左派在革命战略方面的转变之原因作出了说明. 相似文献
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Mark Hughes 《Culture and Organization》2016,22(4):330-347
A story is told here of an investigation into change management's apparent death, provoked by the dubious business novel Who Killed Change [Blanchard, K., J. Britt, P. Zigarmi, and J. Hoekstra. 2009. Who Killed Change? Solving the Mystery of Leading People Through Change. London: Harper Collins Publishers]. The story is told over eight chapters inviting you to investigate competing explanations for the death of change management using the structure of the story arc: stasis, trigger, quest, surprise, critical choice, climax, reversal and resolution. An annoying voice (sometimes interior monologue and at other times dialogue) of another reader keen to inform and frame your understanding of the status of change management remains ever present. The case is solved with the story's resolution providing insights into advantages of investigating over literature reviewing, the problematic/masculine nature of murder metaphors, the academic potential of story arcs and the mystery which characterises organizational change. 相似文献
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Sondra S. Teske Mark H. Weir Timothy A. Bartrand Yin Huang Sushil B. Tamrakar Charles N. Haas 《Risk analysis》2014,34(5):911-928
The effect of bioaerosol size was incorporated into predictive dose‐response models for the effects of inhaled aerosols of Francisella tularensis (the causative agent of tularemia) on rhesus monkeys and guinea pigs with bioaerosol diameters ranging between 1.0 and 24 μm. Aerosol‐size‐dependent models were formulated as modification of the exponential and β‐Poisson dose‐response models and model parameters were estimated using maximum likelihood methods and multiple data sets of quantal dose‐response data for which aerosol sizes of inhaled doses were known. Analysis of F. tularensis dose‐response data was best fit by an exponential dose‐response model with a power function including the particle diameter size substituting for the rate parameter k scaling the applied dose. There were differences in the pathogen's aerosol‐size‐dependence equation and models that better represent the observed dose‐response results than the estimate derived from applying the model developed by the International Commission on Radiological Protection (ICRP, 1994) that relies on differential regional lung deposition for human particle exposure. 相似文献
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Robert J. Mitkus David B. King Mark O. Walderhaug Richard A. Forshee 《Risk analysis》2014,34(4):735-750
The use of thimerosal preservative in childhood vaccines has been largely eliminated over the past decade in the United States because vaccines have been reformulated in single‐dose vials that do not require preservative. An exception is the inactivated influenza vaccines, which are formulated in both multidose vials requiring preservative and preservative‐free single‐dose vials. As part of an ongoing evaluation by USFDA of the safety of biologics throughout their lifecycle, the infant body burden of mercury following scheduled exposures to thimerosal preservative in inactivated influenza vaccines in the United States was estimated and compared to the infant body burden of mercury following daily exposures to dietary methylmercury at the reference dose established by the USEPA. Body burdens were estimated using kinetic parameters derived from experiments conducted in infant monkeys that were exposed episodically to thimerosal or MeHg at identical doses. We found that the body burden of mercury (AUC) in infants (including low birth weight) over the first 4.5 years of life following yearly exposures to thimerosal was two orders of magnitude lower than that estimated for exposures to the lowest regulatory threshold for MeHg over the same time period. In addition, peak body burdens of mercury following episodic exposures to thimerosal in this worst‐case analysis did not exceed the corresponding safe body burden of mercury from methylmercury at any time, even for low‐birth‐weight infants. Our pharmacokinetic analysis supports the acknowledged safety of thimerosal when used as a preservative at current levels in certain multidose infant vaccines in the United States. 相似文献
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Gabriel L. Schlomer H. Harrington Cleveland Mark E. Feinberg Jessica L. Murray David J. Vandenbergh 《Journal of research on adolescence》2021,31(1):189-203
The most extensively studied influence on adolescent conduct problem behaviors is peers, and the literature points to genetics as one source of individual differences in peer influence. The purpose of this study was to test the hypothesis that an environmental sensitivity genetic index comprised of DRD4, 5‐HTTLPR, and GABRA2 variation would moderate the association between peer and adolescent conduct problems. Latent growth modeling was applied to PROSPER project longitudinal data from adolescents and their peers. Results showed the hypothesis was supported; adolescents with more copies of putative sensitivity alleles were more strongly influenced by their peers. The interaction form was consistent with differential susceptibility in follow‐up analyses. Strengths and weaknesses of genetic aggregates for sensitivity research are discussed. 相似文献
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Mark Cohen 《Theory and Society》2014,43(2):139-168
In the 1860s and 1870s, the feudal monarchy of the Tokugawa shogunate, which had ruled Japan for over two centuries, was overthrown, and the entire political order it had commanded was dismantled. This immense political transformation, comparable in its results to the great social revolutions of the seventeenth through nineteenth centuries in the West, was distinctive for lacking a major role for mass political mobilization. Since popular political action was decisive elsewhere for both providing the force for social revolutions to defeat old regimes and for pushing revolutionary leaders to more radical policies, the Meiji Restoration’s combination of revolutionary outcomes with conservative personnel and means is puzzling. This article argues that previous accounts fail to explain why a group of relatively low-status samurai—administrative functionaries with some hereditary political privileges but in fact little secure power within the old regime—was able to overcome far more deeply entrenched political actors. To explain this, it is necessary to distinguish clearly between two political processes: the long-standing political relations of feudal monarchy and magnate lords and the unprecedented emergence of independent samurai political action and organizations cutting across domain boundaries. It was the interaction of these two processes that produced the overthrow of the Tokugawa and enabled the revolutionary outcomes that followed it. This article’s revised explanation of the Meiji Restoration clearly places it within the same theoretical parameters as the major revolutions of the seventeenth century and later. 相似文献