Analysis of a factorial quantal response assay using inverse regression

An inverse regression approach to analyzing quantal response assays with one quanritative independent- variable and any number of qualitative independent variables is presented. A general factorial model ror LQC- inverted relationship and methods of testing hypotheses estimating qulitative Interest are developed. This naper provides a modified method of analysis which is easier to apply than previously existing methods.     

Counterexamples in unbalanced two-way analysis of variance

Recommended methods for analyzing unbalanced two-way data may be classified into two major categories:the parametric interpretation approach and the model comparison approach. Each approach has its advantages and its drawbacks. The main drawback of the parametric interpretation approach is non-orthogonality.For the model comparison approach the main drawback is the dependence of the hypothesis tested on the cell sizes. In this paper we provide examples to illustrate these drawbacks.     

(M,S)-optimal row-column designs

Row-column designs may be considered to have two blocking schemes, namely the treatments by rows and treatments by columns component block designs. The (M,S)-optimality criterion is applied to row-column designs, and che connection between the (M,S)-optimal design and its component block designs is demonstrated.     

Ban Estimation for Chi-Square Test Criteria in Categorical Data

This expository paper describes some recent work that further develops the theory of BAN estimators and the related chi-scuare test statistics.The extensions are in several directions: (a) the class of regular estimators is broadened by permitting extraneous random elements; (b) more general models are permitted under the constraint equations specification; and (c) BAN estimators are defined for general models combining features of two types of specification.In particular, WLS estimators are shown to be BAN.     

On the asymptotic efficiency of moment and maximum likelihood estimators in the three-parameter inverse gaussian distribution

The asymptotic distribution of estimators generated by the methods of moments and maximum likelihood are considered. Simple formulae are provided which enable comparisons of asymptotic relative efficiency to be effected.     

Experimental designs and their efficiencies for spatially correlated observations in two dimensions

Optimality of experimental designs for spatially correlated observations is investigated.come two dimensional correlation structures are discussed and an attempt has been made to find optimal or nearly optimal design for each sitution.The solution lend to designs similar to that used for repeated measurements.The relative efficiency of the proposed designs in comparison to randomized latin square designs is tabulated for some cases.     

Asymptotic tests and monte carlo studies associated with the multiplicative interaction model

Several authors have proposed approximations to percentage points required for testing certain hypotheses associated with the multiplicative interaction model. Alternative approximations based on the asymptotic joint distribution of the characteristic roots of a noncentral Wishart matrix are proposed in this paper. The type I error rates of the resulting tests and the existing procedures are then compared using Monte Carlo methods.     

Empirical Likelihood Inference for the Rao‐Hartley‐Cochran Sampling Design

The Hartley‐Rao‐Cochran sampling design is an unequal probability sampling design which can be used to select samples from finite populations. We propose to adjust the empirical likelihood approach for the Hartley‐Rao‐Cochran sampling design. The approach proposed intrinsically incorporates sampling weights, auxiliary information and allows for large sampling fractions. It can be used to construct confidence intervals. In a simulation study, we show that the coverage may be better for the empirical likelihood confidence interval than for standard confidence intervals based on variance estimates. The approach proposed is simple to implement and less computer intensive than bootstrap. The confidence interval proposed does not rely on re‐sampling, linearization, variance estimation, design‐effects or joint inclusion probabilities.     

The size-density hypothesis in Great Britain: Analysis of a deviant case

Recent studies have found size of territorial units to vary inversely with population density, the only exception to this regularity being Great Britain, where size and density were found to be unrelated. The present research accounts for this anomaly by demonstrating Britain's historical conformity to the size-density relation. The size-density hypothesis is further supported by direct test, made possible by a recent reorganization of british counties. Results show that reorganization has restored the expected inverse relation between size and density and has restructured the size and density of counties in a manner precisely specified by underlying theory.