The Airline Discount Fare Allocation Problem

This paper describes a useful extension of the well-known, single-period inventory or newsboy problem. Given a fixed number of identical seats available on a scheduled airline flight, what percentage should be offered for early sale at a predetermined discount fare and what percentage reserved for later sale at a higher full fare? This two-tiered pricing strategy with early discount pricing might be appropriate in any situation in which the price sensitivity of the inventoried items decreases as the end of the period approaches. Similar to the newsboy problem solution, the decision rule that maximizes expected profit is expressed as a simple function of the percentage difference in the two fares and two carefully defined probabilities.     

Polymorphism-screening: genetic testing for predisposition—guidance for technology assessment

Health policy is increasingly confronted with the demand for financing genetic testing on inherited susceptibility to disease. Tests on polymorphism/SNP associated with multicausal and chronic conditions are already offered in private commercial institutions or in academic hospitals. The increasing pressure on public health services to offer SNP testing leads to first methodological approaches for a generally valid regulatory framework applicable for inclusion or refusal of genetic tests into the public health services. Systematic search in Medline, Embase and the Web for methodological papers or guidelines for the assessment of polymorphism-screening. Since genetic testing has not only clinical and economic effects on health care, but also primarily ethical consequences by profiling our understanding of “health” and “disease”, this paper gives an overview of relevant aspects and background information to consider in the assessment of genetic tests. Although 2–3 million SNPs are identified and the journals are full of reported “significant” associations between disease and mutation, only a few can be replicated unequivocally. The ACCE (Analytic and Clinical Validity, Clinical utility; Ethical, legal and social implications)-framework was developed by the Center of Disease Control for the assessment of genetic testing. This standardised appraisal approach proposes collecting and evaluating: (a) Prevalence, genotype-/phenotype-relation. (b) Clinical presentation: natural history; the different expressions of disease. (c) Performance of the genetic test. (d) Implications for therapy and prevention. (e) Conclusion for clinical applications of risk-profiling of health on their susceptibility to disease and/or for clarification of disease for therapy planning. Since genetic testing is urging its way into the health care system, the actual danger is, that population screening starts before valid evidence from big prospective studies have been carried out and delivered proofs of direct causal associations. Before diffusing into the health care system we are suggesting to take a cautious and standardised approach.     

Shame,Peer, and Oscillating Frames in DWI Conviction: Extending Goffman's Sociological Landscape

Goffman argues that “the interaction order” is a substantive domain autonomous from formal social organization. His scholarship generally analyzes the interaction order in its autonomous workings but neglects the areas in which it is legally regulated. Analyzing the case of legal detention and conviction for the offense of driving while intoxicated (DWI), the article illustrates and extends Goffman's paradigm. A DWI conviction is the result of the legal system's response to distortion at the level of the interaction order. Conviction creates new interactive frames. The interaction order resists the official moral definition of DWI.     

Comparison of ergonomic risk assessment outputs from Rapid Upper Limb Assessment and the Strain Index for tasks in automotive assembly plants

This paper compares the ergonomic risk assessment of a task for the upper extremities as determined by Rapid Upper Extremity Assessment (RULA) and the Strain Index (SI). The ergonomic risk to the upper extremities of 244 automotive assembly plant tasks were evaluated using RULA and SI. The outcomes of each tool were compared for each task. Results from this study provide practical insight into the methods used in each tool. This study compared only the ergonomic risk outputs from each tool; it does not pursue the question of which tool best predicts injury. The kappa score was 0.11, indicating little agreement between the outputs of the two tools. This is supported by the lack of monotonicity with a gamma score of 0.1. These results indicate that the risk assessment outcome of these two ergonomic assessment tools for the upper extremities do not agree.     

Multiple sclerosis and employment barriers: a systemic perspective on diagnosis and intervention

Although they have a recent work history, 70 to 80% of adults with multiple sclerosis are unemployed following their diagnosis. This high rate of unemployment constitutes a great loss of potential to the American economy. To help individuals with multiple sclerosis (MS) return to work or retain employment, rehabilitation professionals must understand the barriers resulting in unemployment and implement interventions to reduce or remove those concerns. In this article, Hershenson's systemic model of rehabilitation counseling is presented as a diagnostic scheme for identifying barriers to employment. Counselor consultation on barrier removal via reasonable accommodation is presented as one example of a rehabilitation intervention consistent with the systemic diagnostic model.     

Barriers to exercise behavior among older adults: a focus-group study

Longer life expectancy, rapid population growth, and low exercise-participation rates of adults 65 and older justify the need for better understanding of older adults' exercise behavior. The objectives of this focus-group study were to determine barriers to the exercise behavior of older adults. Six focus groups, three with exercisers and three with nonexercisers, were conducted at various sites throughout Rhode Island. The majority (n = 57) of the 66 individuals who participated were women, and all stated that they were 65 and older. Results from the focus-group data identified 13 barriers to exercise behavior. The most significant barriers mentioned by nonexercisers were fear of falling, inertia, and negative affect. Exercisers identified inertia, time constraints, and physical ailments as being the most significant barriers to exercise. Implications from these focus-group data can be useful in the development of exercise interventions for older adults, which could increase exercise participation.     

Project Employ: engineering hope and breaking down barriers to homelessness

The homeless population in the US has dramatically increased in the past two decades. People who are homeless often lack skills sets such as stress management and social skills, independent living skills, and skills for vocational and leisure engagement. Best practice vocational education and training programs for individuals who are homeless recognize that success in the worker role often hinges on a person's capacity to manage day-to-day living. Life skills and pre-employment training are essential components of vocational programs but no more important than interpersonal skill development including anger management, developing self esteem and motivation, building goal setting capacity, and skills for money management, personal budgeting and self-advocacy. These areas of performance have all been traditionally included in occupational therapy's domain of practice. This article describes Project Employ, a grant funded supportive employment program that has grown out of collaboration between Duquesne University's Department of Occupational Therapy and Bethlehem Haven, an emergency shelter and residential recovery program and primary service provider for homeless people in Pittsburgh, Pennsylvania. The purpose of this article is to describe the history, structure and outcomes of Project Employ.     

Perspectives on scientific inquiry: Ethics in the conduct of rehabilitation research

The article examines ethical considerations related to the design and implementation of rehabilitation research. The authors' primary thesis is that ethical research practice requires rehabilitation and disability studies scholars to (a) adhere to the standards of conduct promulgated in the canons of ethics of such organizations as the American Psychological Association, the American Counseling Association, and the American Rehabilitation Counseling Association in all interactions with people with disabilities and (b) maintain vigilance in protecting the rights and safety of participants in specific investigations.     

Inclusion and transition: Partners in progress or policy paradox?

The article examines the compatibility of inclusion and transition, two of the most important reforms to affect the field of special education in recent years. The main premise is that the noble ideals associated with full inclusion have the potential to contravene the delivery of responsive and proven-effective career services for students with disabilities as they make the transition from public schools to the world of work. Additional emphasis is placed on casting inclusion and transition within the context of contemporary reforms in general education, most notably the quest for academic excellence and the related practice of high-stakes testing.