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151.
Public and nonprofit organizations need to make strategic choices about where to invest their resources. They also need to expose hidden managerial assumptions and lack of adequate knowledge that prevent the attainment of consensus in strategic decision making. The approach we developed and tested in the field used a dynamic, three‐dimensional model that tracks individual programs in an organization's portfolio on their contribution to mission, money, and merit. The first dimension measures whether the organization is doing the right things; the second, whether it is doing things right financially; and the third, whether it doing things right in terms of quality. Senior managers provide their own evaluations of the organization's programs. Both the consensus view and the variation in individual assessments contribute to an improved managerial understanding of the organization's current situation and to richer discussions in strategic decision making. In field tests, this visual model proved to be a useful and powerful tool for illuminating underlying assumptions and variations in knowledge among managers facing the complex, multidimensional tradeoffs needed in strategic decision making. 相似文献
152.
Stevan Harnad Tim Brody Franois Vallires Les Carr Steve Hitchcock Yves Gingras Charles Oppenheim Heinrich Stamerjohanns Eberhard R. Hilf 《Serials Review》2004,30(4):310-314
The research access/impact problem arises because journal articles are not accessible to all of their would-be users; hence, they are losing potential research impact. The solution is to make all articles Open Access (OA; i.e., accessible online, free for all). OA articles have significantly higher citation impact than non-OA articles. There are two roads to OA: the “golden” road (publish your article in an OA journal) and the “green” road (publish your article in a non-OA journal but also self-archive it in an OA archive). Only 5% of journals are gold, but over 90% are already green (i.e., they have given their authors the green light to self-archive); yet only about 10–20% of articles have been self-archived. To reach 100% OA, self-archiving needs to be mandated by researchers' employers and funders, as the United Kingdom and the United States have recently recommended, and universities need to implement that mandate. 相似文献
153.
154.
155.
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical
data are intrinsically stochastic and tend to be observed by means of discrete-time sampling systems, which are often limited
in their completeness. In this paper we explore how to make Bayesian inference for the kinetic rate constants of regulatory
networks, using the stochastic kinetic Lotka-Volterra system as a model. This simple model describes behaviour typical of
many biochemical networks which exhibit auto-regulatory behaviour. Various MCMC algorithms are described and their performance
evaluated in several data-poor scenarios. An algorithm based on an approximating process is shown to be particularly efficient. 相似文献
156.
In this paper, we deal with a discrete-time multiserver retrial queue with finite population. Firstly, we study the Markov chain at the epochs immediately after slot boundaries making emphasis on the computation of its steady-state distribution. Then, the main performance measures are investigated. Besides, we simulate the waiting time of a customer in the retrial group under three different queueing policies. Some numerical examples are given to illustrate the analysis. 相似文献
157.
The authors provide an overview of optimal scaling results for the Metropolis algorithm with Gaussian proposal distribution. They address in more depth the case of high‐dimensional target distributions formed of independent, but not identically distributed components. They attempt to give an intuitive explanation as to why the well‐known optimal acceptance rate of 0.234 is not always suitable. They show how to find the asymptotically optimal acceptance rate when needed, and they explain why it is sometimes necessary to turn to inhomogeneous proposal distributions. Their results are illustrated with a simple example. 相似文献
158.
D. R. Cox 《Journal of the Royal Statistical Society. Series A, (Statistics in Society)》2003,166(2):241-246
Summary. Possible health hazards from mobile phones arise from the use of the phones themselves and via the base stations that relay signals. Except for an increase in traffic accidents induced by the use of mobile phones in cars the evidence for a health hazard is at most indirect, but it cannot be entirely dismissed; the phones have not been widely used for sufficiently long for direct epidemiological studies to have high sensitivity for detecting any induced incidence of cancer, for example. The background and evidence are briefly reviewed and the steps taken in the UK to make information widely available described. 相似文献
159.
Julia R. Irwin 《Infancy》2003,4(4):503-516
This study examined whether perceivers can detect infant distress in the visual and acoustic signals within the cry. Parent and nonparent perceivers rated distress in 3‐, 6‐, 8‐, and 12‐month‐old infants' cries that were manipulated to separate facial, vocal, and bodily action. Mean perceiver ratings differed for high‐ and low‐distress cries at each infant age on the basis of facial and vocal action, but not bodily movement. Perceivers rated the cry sound as more distressed and the cry face as less distressed with increasing infant age. Parents rated the cries as less distressed overall than did nonparents. The results suggest that information about distress is available for perceivers in the crying infant's face and voice. 相似文献
160.
Christopher R. Browning Matisa Olinger‐Wilbon 《Journal of marriage and the family》2003,65(3):730-745
We examine the relationship between neighborhood structural characteristics, social organization, and the sexual partnering practices of adults. Analyses of 1990 census and 1995–1997 survey‐based data on Chicago neighborhoods and adult sexual activity reveal for men a number of neighborhood influences on sexual partnering practices. First, residential stability is negatively associated with having a short‐term sexual partner in the last year. Second, neighborhood social ties are positively associated with short‐term sexual partnering in neighborhoods with low levels of collective efficacy—the combination of cohesion and shared expectations for beneficial action among neighbors—but this effect is substantially reduced as collective efficacy increases. Moreover, neighborhood collective efficacy and social ties mediate the effect of residential stability on sexual partnering practices. Neighborhood characteristics were not associated with short‐term sexual partnering for women. 相似文献