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331.
The effect of using the average dose rate over a lifetime as a representative measure of exposure to carcinogens is investigated by comparing the true theoretical multistage intermittent-dosing lifetime low-dose excess risk to the theoretical multistage continuous-dosing lifetime risk corresponding to the average lifetime dose rate. It is concluded that low-dose risk estimates based on the average lifetime dose rate may overestimate the true risk by several orders of magnitude, but that they never underestimate the true risk by more than a factor of k/r, where k is the total number of stages in the multistage model and r is the number of stages that are dose-related. 相似文献
332.
Manchester RA 《Journal of American college health : J of ACH》2003,51(4):171-2; author reply 173-4
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Population Research and Policy Review - How diverse is American society and are Americans becoming more or less diverse? Contemporary discussions claim high and increasing diversity, but analyze... 相似文献
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Ralph Anderson 《Journal of Social Distress and the Homeless》1996,5(4):369-380
Successful adaptation to street life requires that risk of violence, an often present aspect of this lifestyle, be reduced to as low a level as possible. This means knowing the informal rules which permit avoiding the pitfalls of street life. It is argued in this paper that safety and security are a function of interactions occurring within a specific place, with particular associates, and involving safe and unsafe behavior. Carelessness with respect to any of these factors can result in victimization. These issues are discussed using survey and ethnographic data collected in Chattanooga. 相似文献
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The excess cancer risk that might result from exposure to a mixture of chemical carcinogens usually must be estimated using data from experiments conducted with individual chemicals. In estimating such risk, it is commonly assumed that the total risk due to the mixture is the sum of the risks of the individual components, provided that the risks associated with individual chemicals at levels present in the mixture are low. This assumption, while itself not necessarily conservative, has led to the conservative practice of summing individual upper-bound risk estimates in order to obtain an upper bound on the total excess cancer risk for a mixture. Less conservative procedures are described here and are illustrated for the case of a mixture of four carcinogens. 相似文献
338.
Mortality Risks Induced by Economic Expenditures 总被引:5,自引:0,他引:5
Ralph L. Keeney 《Risk analysis》1990,10(1):147-159
Existing evidence shows that lower incomes are associated with higher mortality risks. This paper examines the implications for fatalities when the relationship is interpreted as an induced relationship, meaning that lower incomes will on average lead to higher mortality risks. A model is developed for estimating the number of fatalities possibly induced by economic expenditures. This model accounts for different allocations of the expenditures on family units with varying income levels. Illustrative calculations provide insights about the possible significance of fatalities induced by economic expenditures. These results suggest that some expensive regulations and programs intended to save lives may actually lead to increased fatalities. Important caveats to reduce the likelihood of misinterpreting or misusing the results are included. 相似文献
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