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We discuss the issue of using benchmark doses for quantifying (excess) risk associated with exposure to environmental hazards. The paradigm of low-dose risk estimation in dose-response modeling is used as the primary application scenario. Emphasis is placed on making simultaneous inferences on benchmark doses when data are in the form of proportions, although the concepts translate easily to other forms of outcome data.  相似文献   
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Betrayal by a significant object is seen as primary in causing behavioral and emotional disturbances in incest victims, leading to a pervasive identification with the aggressor and disturbances in object relations development. Identification with the aggressor is understood not as a uniform defense mobilized against a specific affect but as a complex compromise formation which defends against anxiety, while also providing libidinal, aggressive and superego gratifications. Far from simply attempting to overcome the past, identifications thus preserve affects that have become pleasurable and self-defining. Two case studies of adolescent girls illustrate how treatment can help victims recognize and begin to forego the sadomasochistic pleasure derived from these identifications, a relinquishment necessary for true mastery.  相似文献   
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There was a time in this fair land when the railroad did not run When the wild majestic mountains stood alone against the sun Long before the white man and long before the wheel When the green dark forest was too silent to be real For they looked into the future and what did they see They saw an iron road running from the sea to the sea Bringing the goods to a young growing land All up through the seaports and into their hands From “Canadian Railroad Trilogy” by Gordon Lightfoot The authors thank CPR managers and union officials representing CPR employees for their cooperation and patience in explaining the intricacies of the railroad industry. Special appreciation is extended to Jason Copping, Labour Relations Manager, for his facilitating our initial access to the company.  相似文献   
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Adolescence is often assumed to be the most important period of life for understanding teen childbearing risk. Developmental perspectives challenge that assumption, offering the possibility that early childhood characteristics may have unique and lasting effects on the risk for teen childbearing. This study examined family life risk factors (socioeconomic status, family stress, and parental involvement in education) and how their effects on teen childbearing risk varied, depending on the childhood age at which they were experienced. Prospective life history data from the National Child Development Study of Great Britain were used to study a birth cohort of 4,928 British women, 15.3% of who became pregnant as teens. This study demonstrated that data from early childhood significantly contribute to the understanding of teen childbearing risk.  相似文献   
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