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In longitudinal biomedical studies, there is often interest in the rate functions, which describe the functional rates of change of biomarker profiles. This paper proposes a semiparametric approach to model these functions as the realizations of stochastic processes defined by stochastic differential equations. These processes are dependent on the covariates of interest and vary around a specified parametric function. An efficient Markov chain Monte Carlo algorithm is developed for inference. The proposed method is compared with several existing methods in terms of goodness-of-fit and more importantly the ability to forecast future functional data in a simulation study. The proposed methodology is applied to prostate-specific antigen profiles for illustration. Supplementary materials for this paper are available online.  相似文献   
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本文概述了当前美国有线电视行业/付费视频行业的局势,以及一些重要问题和面临的挑战,展望了未来的视频市场,概述了一个未来视频/宽带市场的战略愿景,然后回归到政策建议及具体的立法和管制行动。这将帮助我们在最短的、可操作的时间内通向一个开放的、非歧视性的、无处不在的宽带网络。  相似文献   
44.
JM Dixie 《Omega》1974,2(3):415-419
A company bidding by sealed tender needs to know the relationship between their bid price and their chances of winning the contract. Previously published models for computing the probability of winning are examined and found to be inaccurate. The problem is reformulated, and a new general predictive model for computing the probability of winning is developed. The method of computation is illustrated by a simple worked example.  相似文献   
45.
Childhood sexual abuse affects both survivors and partners; however, the common therapy modalities for survivors (individual and individual group therapy exclude their partners. In-depth interviews with the husbands of survivors were used to examine partner issues around the survivor's therapy. Several thems, both positive and negative, emerged from the qualitative analysis of the in-depth interviews. The authors suggest that therapists should consider integration conjoint couple therapy as an adjunct to, not a replacement for the traditional modalities of individual and individual group therapy for adult survivors.  相似文献   
46.
In January 2004, the National Collaboration for Youth approved a list of core competencies needed by entry-level youth development workers for effective youth development practice. This chapter provides an overview of these competencies, explaining why and how the list was created, outcomes, and recommendations for next steps.  相似文献   
47.
The Accuracy of Respondent-Coded Occupation   总被引:1,自引:0,他引:1  
This study reports results from a methodological experimentconducted in a national survey to test the accuracy of respondent-codedoccupation. For most uses, we conclude that such measures aresufficiently precise. There are, however, some systematic sourcesof error which the investigator should be aware of.  相似文献   
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Strong, effective communication may be the single most important key to success for any type of executive. Leaders of health care organizations must be able to promote ideas that others will implement, help staff see the value of their work, and have the vision to overcome limitations that stand in the way of progress.  相似文献   
50.
The intent of the present study was to assess the effects of discrimination training only and in combination with frequent safety observations on five participants' safety-related behavior in a simulated office setting. The study used a multiple-baseline design across safety-related behaviors. Across all participants and behavior, safety improved from 53% during the baseline phase to 74% during the training phase, and improved further to 89% during the training plus observation phase. The results show that both discrimination training only and in combination with frequent observations improves safety-related behavior with a medium effect size. The study also measured participants' accuracy of observation, which was the extent of their correct classification of safe and at-risk behavior. Participants' accuracy of observation was above 80% and had little correlation with safety-related behavior. Based on the various measures, conducting observations appears to serve more than a skill acquisition function for the safety-related behavior.  相似文献   
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