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101.
Population and Environment - Air pollution negatively affects individuals’ health and human capital accumulation. For example, students’ school performance is hampered by air pollution...  相似文献   
102.
Lifetime Data Analysis - We present a new method for estimating a change point in the hazard function of a survival distribution assuming a constant hazard rate after the change point and a...  相似文献   
103.
For safe innovation, knowledge on potential human health impacts is essential. Ideally, these impacts are considered within a larger life‐cycle‐based context to support sustainable development of new applications and products. A methodological framework that accounts for human health impacts caused by inhalation of engineered nanomaterials (ENMs) in an indoor air environment has been previously developed. The objectives of this study are as follows: (i) evaluate the feasibility of applying the CF framework for NP exposure in the workplace based on currently available data; and (ii) supplement any resulting knowledge gaps with methods and data from the li fe c ycle a pproach and human r isk a ssessment (LICARA) project to develop a modified case‐specific version of the framework that will enable near‐term inclusion of NP human health impacts in life cycle assessment (LCA) using a case study involving nanoscale titanium dioxide (nanoTiO2). The intent is to enhance typical LCA with elements of regulatory risk assessment, including its more detailed measure of uncertainty. The proof‐of‐principle demonstration of the framework highlighted the lack of available data for both the workplace emissions and human health effects of ENMs that is needed to calculate generalizable characterization factors using common human health impact assessment practices in LCA. The alternative approach of using intake fractions derived from workplace air concentration measurements and effect factors based on best‐available toxicity data supported the current case‐by‐case approach for assessing the human health life cycle impacts of ENMs. Ultimately, the proposed framework and calculations demonstrate the potential utility of integrating elements of risk assessment with LCA for ENMs once the data are available.  相似文献   
104.
This paper investigates cyclical inventory replenishment for a company's regional distribution center that supplies, distributes, and manages inventory of carbon dioxide (CO2)(CO2) at over 900 separate customer sites in Indiana. The company previously experienced high labor costs with excessive overtime and maintained a regular back-log of customers experiencing stockouts. To address these issues we implemented a three-phase heuristic for the cyclical inventory routing problem encountered at one of the company's distribution centers. This heuristic determines regular routes for each of three available delivery vehicles over a 12-day delivery horizon while improving four primary performance measures: delivery labor cost, stockouts, delivery regularity, and driver–customer familiarity. It does so by first determining three sets of cities (one for each delivery vehicle) that must be delivered to each day based on customer requirements. Second, the heuristic assigns the remaining customers in other cities to one of the three “backbone routes” determined in phase 1. And third, it balances customer deliveries on each daily route over the schedule horizon. Through our methodology, we were able to significantly reduce overtime, driving time, and labor costs while improving customer service.  相似文献   
105.
Multinational corporations (MNC) search increasingly for lead market knowledge and technological expertise around the globe. We investigate whether their subsidiaries gain access to these valuable sources of host country knowledge to the same degree as domestic rivals. We develop a theoretical framework for “why” and “how” a lack of embeddedness and legitimacy (liability of foreignness) may translate into additional obstacles for foreign subsidiaries. We test these hypotheses empirically using a broad dataset of more than 1100 firms in Germany. We find that MNCs can compete on an equal footing with host country competitors when it comes to generating impulses for innovations from universities. They are significantly challenged by liabilities of foreignness, though, when host country customers are involved. The disadvantages are especially pronounced when the host country industry is at the technological forefront. We suggest that the disadvantages arising from liability of foreignness in the host country are especially relevant when promising lead customers have to be identified and their tacit and often unarticulated impulses have to be transferred, understood and prioritized. Management recommendations are developed on the basis of these results.  相似文献   
106.
In the present article a few basic multilevel models for longitudinal data are introduced and applied to the Household Income and Labor Dynamics in Australia Survey 10 (HILDA) for demonstrational purposes. The covered models are adaptions of the random-intercept-only model, the random-intercept models and the random- intercept random-slope model with and without level-1 and level-2 predictors to longitudinal data. The modeling of contextual effects is covered. One particularity in longitudinal data is the fact that persons (level-2) may be regarded as the context of the time-varying observations on level-1. To incorporate the macro-level of sociology, it is necessary to expand the model to a third level. A model with three levels is introduced and in addition a simple growth curve model and a multivariate multilevel model are presented.  相似文献   
107.
Sensitive responding to eye cues plays a key role in human social interactions. Pupil size provides subtle cues regarding a social interaction partner's arousal states. The current study assessed infants’ sensitivity to and preference for differences in pupil size. Specifically, we examined White 14-month-old infants’ pupillary responses when viewing own-race and other-race (Asian) eyes with dilating, constricting, and static medium-sized pupils. Our results show that, independent of race, infants’ pupils dilated more when viewing eyes with dynamically changing (dilating and constricting) pupils than when viewing eyes with non-changing, static, and medium-sized pupils. We also measured infants’ looking preferences, showing that, independent of race, infants preferentially attended to eyes with dilated pupils. Moreover, our results show that infants orient more quickly to pupillary changes in own-race eyes than in other-race eyes. These findings demonstrate that infants detect, but do not mimic, changes in pupil size in others and show a preference for eyes with dilated pupils.  相似文献   
108.
109.
Summary. Reversible jump methods are the most commonly used Markov chain Monte Carlo tool for exploring variable dimension statistical models. Recently, however, an alternative approach based on birth-and-death processes has been proposed by Stephens for mixtures of distributions. We show that the birth-and-death setting can be generalized to include other types of continuous time jumps like split-and-combine moves in the spirit of Richardson and Green. We illustrate these extensions both for mixtures of distributions and for hidden Markov models. We demonstrate the strong similarity of reversible jump and continuous time methodologies by showing that, on appropriate rescaling of time, the reversible jump chain converges to a limiting continuous time birth-and-death process. A numerical comparison in the setting of mixtures of distributions highlights this similarity.  相似文献   
110.
With electronic procurement solutions becoming increasingly sophisticated, many firms opt to source these services from third-party providers, effectively transferring (outsourcing) significant responsibility to these services companies. This action, however, entails certain risks, which are oftentimes difficult to assess. To guide managerial practice and to advance academic inquiry in this domain, we identify e-procurement risk factors through a strengths, weaknesses, opportunities, threats analysis, grounded in transaction cost economics (TCE), and propose a risk assessment framework based on the opinions of a group of experts. The approach taken is that of a modified analytic network process methodology, combined with a fuzzy inference system, which is versatile enough to accept the expert opinions in different input formats (such as linguistic variables and ranges). The proposed framework has the capability to aggregate expert judgements’ to estimate risk likelihoods, risk severities and risk factor indices, and derive overall risk magnitudes. The multi-method approach was motivated and is illustrated by a real-life case study of an Indian manufacturing company currently in the process of contract renewal with its existing e-procurement service provider.  相似文献   
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