Ergonomic and individual risk evaluation

The ergonomic risks constitute a vital aspect of study and prevention for the worker's health, especially for people with different capacities. Very job has and implies certain type of risk for the worker's health, depending on the conditions it is done with the use of tools or without them. Aplicated techniques: posturogram, baropodometry, Schober test, biocinemátic chain test, Fukuda test, propioceptiva plataform in personnel with special capabilities.     

Walking in the shoes of others: Experimental testing of dual-interest and empathy in environmental choice

This paper further tests dual interest theory and the metaeconomics approach to environmental choice, recognizing a possible role for empathy–sympathy (the basis for an internalized, shared other-interest) in tempering and conditioning the more fundamental tendency to pursue self-interest. To test, we focus on rivers flowing through agricultural areas carrying sediments, chemicals, and fertilizers which are making their way into downstream rivers and lakes. We conduct a framed laboratory experiment modeling this problem: farmers decide on the usage of conservation technology to lessen impacts on the water quality (i.e. on the commons, the capacity to absorb these wastes) in downstream areas, which is more costly than the alternative intensive technology. The results confirm our hypotheses, demonstrating that Upstream Farmers who practice conservation are tempering profit maximization with empathy-based, environmentally conscious behavior. Such behavior better serves the farmers’ own-interest, and also helps Downstream Water Users. Environmental economics models need to explicitly include empathy–sympathy and the moral–ethical context it produces, providing a more scientific basis for conservation policy and programs.     

Biomechanics-based active control of bedding support properties and its influence on sleep

Proper body support plays an import role in the recuperation of our body during sleep. Therefore, this study uses an automatically adapting bedding system that optimises spinal alignment throughout the night by altering the stiffness of eight comfort zones. The aim is to investigate the influence of such a dynamic sleep environment on objective and subjective sleep parameters. The bedding system contains 165 sensors that measure mattress indentation. It also includes eight actuators that control the comfort zones. Based on the measured mattress indentation, body movements and posture changes are detected. Control of spinal alignment is established by fitting personalized human models in the measured indentation. A total of 11 normal sleepers participated in this study. Sleep experiments were performed in a sleep laboratory where subjects slept three nights: a first night for adaptation, a reference night and an active support night (in counterbalanced order). Polysomnographic measurements were recorded during the nights, combined with questionnaires aiming at assessing subjective information. Subjective information on sleep quality, daytime quality and perceived number of awakenings shows significant improvements during the active support (ACS) night. Objective results showed a trend towards increased slow wave sleep. On the other hand, it was noticed that % N1-sleep was significantly increased during ACS night, while % N2-sleep was significantly decreased. No prolonged N1 periods were found during or immediately after steering.     

Enabling robust assessment of QTc prolongation in early phase clinical trials

Since the implementation of the International Conference on Harmonization (ICH) E14 guideline in 2005, regulators have required a “thorough QTc” (TQT) study for evaluating the effects of investigational drugs on delayed cardiac repolarization as manifested by a prolonged QTc interval. However, TQT studies have increasingly been viewed unfavorably because of their low cost effectiveness. Several researchers have noted that a robust drug concentration‐QTc (conc‐QTc) modeling assessment in early phase development should, in most cases, obviate the need for a subsequent TQT study. In December 2015, ICH released an “E14 Q&As (R3)” document supporting the use of conc‐QTc modeling for regulatory decisions. In this article, we propose a simple improvement of two popular conc‐QTc assessment methods for typical first‐in‐human crossover‐like single ascending dose clinical pharmacology trials. The improvement is achieved, in part, by leveraging routinely encountered (and expected) intrasubject correlation patterns encountered in such trials. A real example involving a single ascending dose and corresponding TQT trial, along with results from a simulation study, illustrate the strong performance of the proposed method. The improved conc‐QTc assessment will further enable highly reliable go/no‐go decisions in early phase clinical development and deliver results that support subsequent TQT study waivers by regulators.     

Nonparametric control charts based on runs and Wilcoxon-type rank-sum statistics

In this article, we introduce three new distribution-free Shewhart-type control charts that exploit run and Wilcoxon-type rank-sum statistics to detect possible shifts of a monitored process. Exact formulae for the alarm rate, the run length distribution, and the average run length (ARL) are all derived. A key advantage of these charts is that, due to their nonparametric nature, the false alarm rate (FAR) and in-control run length distribution is the same for all continuous process distributions. Tables are provided for the implementation of the charts for some typical FAR values. Furthermore, a numerical study carried out reveals that the new charts are quite flexible and efficient in detecting shifts to Lehmann-type out-of-control situations.     

Non-asymptotic sequential confidence regions with fixed sizes for the multivariate nonlinear parameters of regression

In this paper we consider a sequential design for the estimation of nonlinear parameters of regression with guaranteed accuracy. Non-asymptotic confidence regions with fixed sizes for the least squares estimates are used. The obtained confidence region is valid for finite numbers of data points when the distributions of the observations are unknown.     

Toward a multi‐ethnic public sphere? Media consumption in highly diverse districts in Spain

This article examines media consumption in highly diverse districts in Spain as representative of recent changes in this field due to new immigration to countries in Southern Europe in times of crisis. Drawing on findings from two surveys, we observed a decrease in access to media specifically aimed at audiences of minority cultures between 2010 and 2012. It is suggested that this decline is not due to a modification in media consumption habits by minority groups, but rather the economic crisis of 2008. Furthermore, we study the consumption of minority media by natives: we observe that youth and more educated individuals consume other cultures’ minority media to a greater extent, particularly the press, radio, and Internet news sources. We suggest that elements are present that public administrations could utilize to further develop a multi‐ethnic public sphere. Finally, we explore the emergence of a new transnational dimension to the multi‐ethnic public sphere.     

Five Star Teacher: In-Service on the Move

Teachers learned knowledge, skills, values, and dispositions through spending significant amounts of time working with heritage sites as they learned more about social studies. Elementary social studies teachers engaged in teacher in-service to increase their abilities to meet geography standards. Teacher professional development that caused instructors to engage with cultural and historic sites benefited them and should be considered as well as other models of teacher in-service. Teachers used study travel opportunities to engage in geographic investigation and exploration to accomplish inquiry. Teachers determined that extended time was required to experience the place, to value it, and to harbor the disposition to teach about it; they learned in-depth content from spending time on-site, and they learned skills to extract knowledge from site through reading the landscape. Teachers encountered multiple perspectives, technology, and controversial issues through their studies of regions in the Ohio River Valley. Teachers of elementary social studies may wish to consider this type of professional development to understand a sense of place and how it relates to the curriculum they teach.     

Alone and adrift: The association between mass school shootings,school size,and student support

Background

School shootings have approached epidemic levels in recent years. While mental illness is undoubtedly involved in nearly all cases of mass school violence, we sought to determine how environmental context may exacerbate preexisting personal factors. The present study investigated the associations between mass school shootings, school enrollment size, student–teacher ratios, and student transitions.