Optimal design of complex experiments with qualitative factors of influence

A complex experiment with qualirarive factors influencing the outcome of the experiment can be seen as a general ANOVA setup. A design of such an experiment will be the assignment at which of the possible levels of the factors the actual experiment should be performed. In this paper optimal designs of such experiments will be characterized with respect to three different optimality criteria including the so called uniform optimality of a design. The possible applications of the main optimization result providing these characterizations can be used to more general experiments. The particular results on these generalizations will be indicated at the end of this paper.     

Empirical bayes interval estimates involving uniform distributions

Bayesian and empirical Bayesian decision rules are exhibited for the interval estimation of the parameter 0 of a Uniform (0,θ) distribution. The estimate ?,δ>resulting in the interval [?,?+δ]suffers loss given by L(?,δ>,θ)=1-[?≦e≦?+δ]+c₁((?-θ)²+(?+δ?θ)²))+c₂δ. The solution is presented for prior distributions G which have bounded support, no point masses,∫θ^?mdG(θ)<∞ and for some integer m. An example is presented involving a particular parametric form for G and rates of risk convergence in the empirical Bayes problem for this example are calculated.     

On gart's test for interaction of second order

Gart (1972) ottered a Statistic on testing the hypothesis of no second-order interaction in a 2×s×t contingency table. The statistic was tn be used as an asymptotic chi-square with (s-1) (t-1) degrees of freedom. We show that this statistic suiters from the drawback that unless certain side conditions hold, the statistic would reject the null hypothesis with probability approaching one asymptotically even in the null case. Hence the statistic is not strictly valid for the hypothesis for which it was intended.     

On the recovery of intra- and interblock information in n-ary designs

This note presents an extension of Q-method of analysis for binary designs given by Rao (1956) to n-ary balanced and partially balanced block designs. Here a linked n-ary block (LNB) design is defined as the dual of balanced n-ary (BN) design. Having a note on Yates’ (1939, 1940) method of P-analysis, we further extend the expressions for binary linked block (LB) designs given by Rao (1956) to linked n-ary block (LNB) designs which admit easy estimation of parameters for these type of all n-ary designs.     

Standard and goodness-of-fit parameter estimation methods for the three-parameter lognormal distribution

A class of goodness-of-fit estimators is found to provide a useful alternative in certain situations to the standard maximum likelihood method which has some undesirable estimation characteristics for estimation from the three-parameter lognormal distribution. The class of goodness-of-fit tests considered include the Shapiro-Wilk and Filliben tests which reduce to a weighted linear combination of the order statistics that can be maximized in estimation problems. The weighted order statistic estimators are compared to the standard procedures in Monte Carlo simulations. Robustness of the procedures are examined and example data sets analyzed.     

Dynamic Copula-Based Markov Time Series

This article examines a test procedure for checking the constancy of serial dependence via copulas for Markov time series data. It also provides a copula-based modeling approach for the dynamic serial dependence. Various parametric families of copulas offering different dependent structures are investigated. A score test is proposed for checking the constancy of a copula parameter. The score test is constructed and its asymptotic null distribution established under a two-stage estimation procedure. The test does not require specification of the probability distribution for the copula parameter. To capture the dynamics of dependence structure over time, autoregressive moving average and exponential type models are proposed. Illustrations are given based on simulated data and historic coffee prices data.     

IPPS Sampling Plans Excluding Adjacent Units

The concept of inclusion probability proportional to size sampling plans excluding adjacent units separated by at most a distance of m (≥ 1) units {IPPSEA plans} is introduced. IPPSEA plans ensure that the first-order inclusion probabilities of units are proportional to size measures of the units, while the second-order inclusion probabilities are zero for pairs of adjacent units separated by a distance of m units or less. IPPSEA plans have been obtained by making use of binary, proper, and unequireplicated block designs and linear programing approach. The performance of IPPSEA plans using Horvitz–Thompson estimator of population total has been compared with existing sampling plans such as simple random sampling without replacement (SRSWOR), balanced sampling plans excluding adjacent units {BSA (m) plans}, probability proportional to size with replacement, Hartley and Rao's plan (1962 Hartley , H. O. , Rao , J. N. K. ( 1962 ). Sampling with unequal probabilities and without replacement . Ann. Math. Statist. 33 : 350 – 374 .[Crossref] , [Google Scholar]), Rao et al.'s strategy (1962 Rao , J. N. K. , Hartley , H. O. , Cochran , W. G. ( 1962 ). On a simple procedure of unequal probability sampling without replacement . J. Roy. Statist. Soc. B 24 : 482 – 491 . [Google Scholar]), and Sampford's IPPS plan (1967 Sampford , M. R. ( 1967 ). On sampling without replacement with unequal probabilities of selection . Biometrika 54 ( 3 ): 499 – 513 .[Crossref], [PubMed] , [Google Scholar]) using a real life population. Unbiased estimation of Horvitz–Thompson estimator of population total is not possible in these types of plans because some of the second-order inclusion probabilities are zero. To resolve this problem, one approximate variance estimation technique has been suggested.     

A Robust Procedure in Nonlinear Models for Repeated Measurements

Nonlinear regression models arise when definite information is available about the form of the relationship between the response and predictor variables. Such information might involve direct knowledge of the actual form of the true model or might be represented by a set of differential equations that the model must satisfy. We develop M-procedures for estimating parameters and testing hypotheses of interest about these parameters in nonlinear regression models for repeated measurement data. Under regularity conditions, the asymptotic properties of the M-procedures are presented, including the uniform linearity, normality and consistency. The computation of the M-estimators of the model parameters is performed with iterative procedures, similar to Newton–Raphson and Fisher's scoring methods. The methodology is illustrated by using a multivariate logistic regression model with real data, along with a simulation study.     

Second-Order Response Surface Model with Neighbor Effects

This article considers the second-order response surface model in which the experimental units, i.e., plots experience the neighbor effects from immediate left and right neighboring plots assuming the plots to be placed adjacent linearly with no gaps. Conditions have been derived for the estimation of coefficients of second-order response surface model. A method of constructing designs for fitting second-order response surface in the presence of neighbor effects has been developed. The designs so obtained are found to be rotatable.     

An extension of bayesian measure of information to regression

This paper extends Lindley's measure of average information to the linear model, E(Y∣ß) = Xß. An expression which quantifies the average amount of information provided by the nxl vector of observations Y about the pxl vector of coefficient parameters ß will be derived. The effect of the structure of the regressor matrix, X, on the information measure is discussed. An information theoretic optimal design is characterized. Some applications are suggested.