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161.
Reanalysis of the DEMS Nested Case‐Control Study of Lung Cancer and Diesel Exhaust: Suitability for Quantitative Risk Assessment 下载免费PDF全文
Kenny S. Crump Cynthia Van Landingham Suresh H. Moolgavkar Roger McClellan 《Risk analysis》2015,35(4):676-700
The International Agency for Research on Cancer (IARC) in 2012 upgraded its hazard characterization of diesel engine exhaust (DEE) to “carcinogenic to humans.” The Diesel Exhaust in Miners Study (DEMS) cohort and nested case‐control studies of lung cancer mortality in eight U.S. nonmetal mines were influential in IARC's determination. We conducted a reanalysis of the DEMS case‐control data to evaluate its suitability for quantitative risk assessment (QRA). Our reanalysis used conditional logistic regression and adjusted for cigarette smoking in a manner similar to the original DEMS analysis. However, we included additional estimates of DEE exposure and adjustment for radon exposure. In addition to applying three DEE exposure estimates developed by DEMS, we applied six alternative estimates. Without adjusting for radon, our results were similar to those in the original DEMS analysis: all but one of the nine DEE exposure estimates showed evidence of an association between DEE exposure and lung cancer mortality, with trend slopes differing only by about a factor of two. When exposure to radon was adjusted, the evidence for a DEE effect was greatly diminished, but was still present in some analyses that utilized the three original DEMS DEE exposure estimates. A DEE effect was not observed when the six alternative DEE exposure estimates were utilized and radon was adjusted. No consistent evidence of a DEE effect was found among miners who worked only underground. This article highlights some issues that should be addressed in any use of the DEMS data in developing a QRA for DEE. 相似文献
162.
In this paper, we analyze the ethical issues of using honesty and integrity tests in employment screening. Our focus will be on the United States context: legal requirements related to applicant privacy differ in other countries, but we posit that our proposed balancing test is broadly applicable. We start by discussing why companies have ethical and legal obligations, based on a stakeholder analysis, to assess the integrity of potential employees. We then move to a consideration of how companies currently use background checks as a pre‐employment screening tool, noting their limitations. We then take up honesty and integrity testing, focusing particularly on the problems of false positives and due process. We offer a balancing test for the use of honesty and integrity testing that takes in three factors: (1) the potential harm posed by a dishonest employee in a particular job, (2) the linkage between the test and the assessment process, and (3) the accuracy and validity of the honesty and integrity test. We conclude with implications for practice and future research. 相似文献
163.
我国证券市场中的噪声交易研究——基于一个“机构噪声交易者—散户噪声交易者模型”的分析 总被引:1,自引:0,他引:1
本文从行为金融理论发展的大背景出发,以噪声交易作为研究主题。首先介绍了基于行为金融理论的噪声交易理论;接着简要介绍了噪声交易理论的基本模型—DSSW模型,为将其应用于我国证券市场的实证并提出一个改良模型做好理论铺垫;然后在DSSW模型的基础上,结合我国证券市场的实际情况,原创性地提出了一个我国证券市场机构噪声交易者一散户噪声交易者模型,以分析说明我国噪声交易者的生存机制及噪声交易对证券市场的影响,并得出相应的启示和政策建议。 相似文献
164.
Charles Bellemare Sabine Krger Arthur Van Soest 《Econometrica : journal of the Econometric Society》2008,76(4):815-839
We combine choice data in the ultimatum game with the expectations of proposers elicited by subjective probability questions to estimate a structural model of decision making under uncertainty. The model, estimated using a large representative sample of subjects from the Dutch population, allows both nonlinear preferences for equity and expectations to vary across socioeconomic groups. Our results indicate that inequity aversion to one's own disadvantage is an increasing and concave function of the payoff difference. We also find considerable heterogeneity in the population. Young and highly educated subjects have lower aversion for inequity than other groups. Moreover, the model that uses subjective data on expectations generates much better in‐ and out‐of‐sample predictions than a model which assumes that players have rational expectations. 相似文献
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166.
This article describes a Delphi‐based expert judgment study aimed at the selection of indicators to identify the occurrence of emerging mycotoxin hazards related to Fusarium spp. in wheat supply chains. A panel of 29 experts from 12 European countries followed a holistic approach to evaluate the most important indicators for different chain stages (growth, transport and storage, and processing) and their relative importance. After three e‐mailing rounds, the experts reached consensus on the most important indicators for each of the three stages: wheat growth, transport and storage, and processing. For wheat growth, these indicators include: relative humidity/rainfall, crop rotation, temperature, tillage practice, water activity of the kernels, and crop variety/cultivar. For the transport and storage stage, they include water activity in the kernels, relative humidity, ventilation, temperature, storage capacity, and logistics. For wheat processing, indicators include quality data, fraction of the cereal used, water activity in the kernels, quality management and traceability systems, and carryover of contamination. The indicators selected in this study can be used in an identification system for the occurrence of emerging mycotoxin hazards in wheat supply chains. Such a system can be used by risk managers within governmental (related) organizations and/or the food and feed industry in order to react proactively to the occurrence of these emerging mycotoxins. 相似文献
167.
文章以笔者前期研究成果和国际通行的理论为依据,通过比较计算宁波与香港的国民经济信息化指数,从一个方面分析了现代国际著名港城国民经济信息化的实际情况及对宁波的启示。 相似文献
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169.
This article aims to investigate parental influence on high-risk behavior by young people. Although research on the topic of perception of risk demonstrates that it is socially constructed, the role of the family in this construction has rarely been studied. Using a French national survey of more than 1,200 young drivers between the ages of 18 and 25, and their parents, we attempt to understand the transmission of risk within families. Our econometric study shows that parents influence both the practices and representations of their children. When parental norms and values are transmitted, they are by no means accepted in a wholly passive way. Indeed, the parental model is in competition with other models that originate from both inside the family (brothers and sisters) and outside it (instructors). Furthermore, parental influence decreases over time as young people become more experienced drivers and construct their own identity with regard to risk. 相似文献
170.
Jan Kees Van Donge 《Development policy review : the journal of the Overseas Development Institute》2007,25(4):473-494
This article offers an alternative view on the emergence of new forms of development co‐operation by analysing the emergence of SWAps in Zambia since the early 1990s. SWAps in Zambia emerged not as part of a grand design but in response to the changing environment in which aid agencies were operating. An examination of the relative success of the health and education SWAps and the spectacular failure of the agriculture SWAp suggests that a flexible approach is more effective than the imposition of a planning template. Furthermore, the failure of the agricultural SWAp has been followed by significant new forms of public/private partnership. 相似文献