Hepatitis B (HB) is a deadly disease that has a severe impact on infected individuals. In China, not only are the incidence and infection rates of HB very high, but also many HB patients suffer from mental illness associated with anxiety and fear because of HB-associated symptoms. This exacerbates the patients’ condition, potentially increasing the risk of mortality. In this paper, we propose a new treatment mode to improve the therapeutic efficiency and patients’ satisfaction with their healthcare. In a single process of this new treatment, several patients with similar disease symptoms are treated by one doctor at the same time. This new treatment mode can not only relieve the anxiety and fear of HB patients, and improve patients’ cognition rate of HB, but also reduce the HB infection rate, slow down the progression of disease symptoms, and shorten the course. If patients with similar disease symptoms are to be grouped together, there is a need to determine the optimal patient batch combination, which can be solved in the new mode, called patient combined problem (PCP). We also constructed a mathematical model of PCP, and present the ant colony (AC) algorithm and Enhanced AC with a P-3-exchange operator for PCP in the new treatment mode in this paper. We also performed an experiment that showed that our proposed algorithms are very fast and effective for solving this problem.
Abstract "Subsistence" and "informal economy" are contrasted in their utility as sociological concepts and their ability to explain a variety of activities in two rural Mississippi Delta communities. Literature on subsistence stresses that the desired outcome of participation is not an increase in income but the social rewards of participation itself. Two underlying dimensions of participation in these activities are documented through the literature and through a confirmatory factor analysis of empirical data: life-style choice and economic strategy. These were constructed into indexes and examined individually and in combination as dependent variables using regressors at the community, household, and individual levels. Community ties were weakly associated with participation in such activities. Whites and those with higher incomes participated more in lifestyle choice oriented activities. Participation in general was statistically related to households needing less weekly income and being of larger size. Potential connections with persistent rural poverty are discussed. 相似文献
In electrical engineering, circuit designs are now often optimized via circuit simulation computer models. Typically, many response variables characterize the circuit's performance. Each response is a function of many input variables, including factors that can be set in the engineering design and noise factors representing manufacturing conditions. We describe a modelling approach which is appropriate for the simulator's deterministic input–output relationships. Non-linearities and interactions are identified without explicit assumptions about the functional form. These models lead to predictors to guide the reduction of the ranges of the designable factors in a sequence of experiments. Ultimately, the predictors are used to optimize the engineering design. We also show how a visualization of the fitted relationships facilitates an understanding of the engineering trade-offs between responses. The example used to demonstrate these methods, the design of a buffer circuit, has multiple targets for the responses, representing different trade-offs between the key performance measures. 相似文献
