A NOTE ON MOMENTS OF PROGRESSIVELY TYPE II CENSORED ORDER STATISTICS

ABSTRACT

Upper and lower bounds for moments of progressively Type II censored order statistics in terms of moments of (progressively Type II censored) order statistics are derived. In particular, this yields conditions for the existence of moments of progressively Type II censored order statistics based on an absolutely continuous distribution function.     

The exact hypothesis test for the shape parameter of a new two-parameter distribution with the bathtub shape or increasing failure rate function under progressive censoring with random removals

This study considers the exact hypothesis test for the shape parameter of a new two-parameter distribution with the shape of a bathtub or increasing failure rate function under type II progressive censoring with random removals, where the number of units removed at each failure time follows a binomial or a uniform distribution. Several test statistics are proposed and one numerical example is provided to illustrate the proposed hypothesis test for the shape parameter. Finally, a simulation study is performed to compare the power performances of all proposed test statistics. We concluded that the test statistic w ₁ is more attractive than other methods as it has better performance than other test statistics for most cases based on the criteria of maximum power.     

Interval estimation for the Pareto distribution based on the progressive Type II censored sample

For the complete sample and the right Type II censored sample, Chen [Joint confidence region for the parameters of Pareto distribution. Metrika 44 (1996), pp. 191–197] proposed the interval estimation of the parameter θ and the joint confidence region of the two parameters of Pareto distribution. This paper proposed two methods to construct the confidence region of the two parameters of the Pareto distribution for the progressive Type II censored sample. A simulation study comparing the performance of the two methods is done and concludes that Method 1 is superior to Method 2 by obtaining a smaller confidence area. The interval estimation of parameter ν is also given under progressive Type II censoring. In addition, the predictive intervals of the future observation and the ratio of the two future consecutive failure times based on the progressive Type II censored sample are also proposed. Finally, one example is given to illustrate all interval estimations in this paper.     

Detecting change in a hazard regression model with right-censoring

The hazard function plays an important role in survival analysis and reliability, since it quantifies the instantaneous failure rate of an individual at a given time point t, given that this individual has not failed before t. In some applications, abrupt changes in the hazard function are observed, and it is of interest to detect the location of such a change. In this paper, we consider testing of existence of a change in the parameters of an exponential regression model, based on a sample of right-censored survival times and the corresponding covariates. Likelihood ratio type tests are proposed and non-asymptotic bounds for the type II error probability are obtained. When the tests lead to acceptance of a change, estimators for the location of the change are proposed. Non-asymptotic upper bounds of the underestimation and overestimation probabilities are obtained. A short simulation study illustrates these results.     

Estimation and comparison of the stress-strength models with more than two states under Weibull distribution and type II censoring scheme

This paper presents the extension of the inferences on the stress-strength reliability in more than two states to the system depending on the ratio of the strength and stress values when the stress and strength follow independent exponential distributions. The main objective of present paper is to consider different method of estimation, under Type II censoring, for the stress-strength models and to compare them, in more than two states, to the system depending on the ratio of the strength and stress values, when the stress and strength follow independent Weibull distributions, sharing the common shape parameter α.     

An alternative procedure for performing a power analysis of Mantel's test

This study proposes a simple way to perform a power analysis of Mantel's test applied to squared Euclidean distance matrices. The general statistical aspects of the simple Mantel's test are reviewed. The Monte Carlo method is used to generate bivariate Gaussian variables in order to create squared Euclidean distance matrices. The power of the parametric correlation t-test applied to raw data is also evaluated and compared with that of Mantel's test. The standard procedure for calculating punctual power levels is used for validation. The proposed procedure allows one to draw the power curve by running the test only once, dispensing with the time demanding standard procedure of Monte Carlo simulations. Unlike the standard procedure, it does not depend on a knowledge of the distribution of the raw data. The simulated power function has all the properties of the power analysis theory and is in agreement with the results of the standard procedure.     

A Phase I/II adaptive design for heterogeneous groups with application to a stereotactic body radiation therapy trial

Dose‐finding studies that aim to evaluate the safety of single agents are becoming less common, and advances in clinical research have complicated the paradigm of dose finding in oncology. A class of more complex problems, such as targeted agents, combination therapies and stratification of patients by clinical or genetic characteristics, has created the need to adapt early‐phase trial design to the specific type of drug being investigated and the corresponding endpoints. In this article, we describe the implementation of an adaptive design based on a continual reassessment method for heterogeneous groups, modified to coincide with the objectives of a Phase I/II trial of stereotactic body radiation therapy in patients with painful osseous metastatic disease. Operating characteristics of the Institutional Review Board approved design are demonstrated under various possible true scenarios via simulation studies. Copyright © 2015 John Wiley & Sons, Ltd.     

Diagnosis Aids in Multivariate Multiple Linear Regression Profiles Monitoring

Diagnosis aids in addition to detecting the out-of-control state is an important issue in multivariate multiple linear regression profiles monitoring; because a large number of parameters and profiles in this structure are involved. In this paper, we specifically concentrate on identification of profile(s) and parameter(s) which have changed during the process in multivariate multiple linear regression profiles structure in Phase II. We demonstrate the effectiveness of our proposed approaches through Monte Carlo simulations and a real case study in terms of accuracy percent.