A Potts‐mixture spatiotemporal joint model for combined magnetoencephalography and electroencephalography data

We develop a new methodology for determining the location and dynamics of brain activity from combined magnetoencephalography (MEG) and electroencephalography (EEG) data. The resulting inverse problem is ill‐posed and is one of the most difficult problems in neuroimaging data analysis. In our development we propose a solution that combines the data from three different modalities, magnetic resonance imaging (MRI), MEG and EEG, together. We propose a new Bayesian spatial finite mixture model that builds on the mesostate‐space model developed by Daunizeau & Friston [Daunizeau and Friston, NeuroImage 2007; 38, 67–81]. Our new model incorporates two major extensions: (i) We combine EEG and MEG data together and formulate a joint model for dealing with the two modalities simultaneously; (ii) we incorporate the Potts model to represent the spatial dependence in an allocation process that partitions the cortical surface into a small number of latent states termed mesostates. The cortical surface is obtained from MRI. We formulate the new spatiotemporal model and derive an efficient procedure for simultaneous point estimation and model selection based on the iterated conditional modes algorithm combined with local polynomial smoothing. The proposed method results in a novel estimator for the number of mixture components and is able to select active brain regions, which correspond to active variables in a high‐dimensional dynamic linear model. The methodology is investigated using synthetic data and simulation studies and then demonstrated on an application examining the neural response to the perception of scrambled faces. R software implementing the methodology along with several sample datasets are available at the following GitHub repository https://github.com/v2south/PottsMix . The Canadian Journal of Statistics 47: 688–711; 2019 © 2019 Statistical Society of Canada     

Functional principal component analysis in age–period–cohort analysis of body mass index data by gender and ethnicity

In this paper, we propose a two-stage functional principal component analysis method in age–period–cohort (APC) analysis. The first stage of the method considers the age–period effect with the fitted values treated as an offset; and the second stage of the method considers the residual age–cohort effect conditional on the already estimated age-period effect. An APC version of the model in functional data analysis provides an improved fit to the data, especially when the data are sparse and irregularly spaced. We demonstrate the effectiveness of the proposed method using body mass index data stratified by gender and ethnicity.     

Prediction Error of Small Area Predictors Shrinking Both Means and Variances

The article considers a new approach for small area estimation based on a joint modelling of mean and variances. Model parameters are estimated via expectation–maximization algorithm. The conditional mean squared error is used to evaluate the prediction error. Analytical expressions are obtained for the conditional mean squared error and its estimator. Our approximations are second‐order correct, an unwritten standardization in the small area literature. Simulation studies indicate that the proposed method outperforms the existing methods in terms of prediction errors and their estimated values.     

A review and re‐interpretation of a group‐sequential approach to sample size re‐estimation in two‐stage trials

In this paper, we review the adaptive design methodology of Li et al. (Biostatistics 3 :277–287) for two‐stage trials with mid‐trial sample size adjustment. We argue that it is closer in principle to a group sequential design, in spite of its obvious adaptive element. Several extensions are proposed that aim to make it even more attractive and transparent alternative to a standard (fixed sample size) trial for funding bodies to consider. These enable a cap to be put on the maximum sample size and for the trial data to be analysed using standard methods at its conclusion. The regulatory view of trials incorporating unblinded sample size re‐estimation is also discussed. © 2014 The Authors. Pharmaceutical Statistics published by John Wiley & Sons, Ltd.     

保险集团监管资本套利的理论与实证研究——基于CTE与VaR风险度量方法的分析

为加强保险集团监管,完善中国正在建设的第二代偿付能力管理体系,利用国际上应用广泛的CTE与VaR两种风险度量方法构建监管资本套利模型,对不同条件下保险集团套利策略进行理论研究。根据中国人民财产保险股份有限公司历史数据,运用R软件,首次对保险集团监管资本套利策略进行直观展示和实证检验。研究表明:监管资本套利可以为保险集团节约大量资本,但蕴含一定风险;若监管资本中考虑尾部极端风险,有利于降低监管资本套利风险。     

Likelihood Based Inference in Non-linear Regression Models Using the p* and R* Approach

We develop second order asymptotic results for likelihood-based inference in Gaussian non-linear regression models. We provide an approximation to the conditional density of the maximum likelihood estimator given an approximate ancillary statistic (the affine ancillary). From this approximation, we derive a statistic to test an hypothesis on one component of the parameter. This test statistic is an adjustment of the signed log-likelihood ratio statistic. The distributional approximations (for the maximum likelihood estimator and for the test statistic) are of second order in large deviation regions.     

A note on separated data and exact likelihood-ratio p-values in logistic regression

Exact conditional p-values based on the likelihood-ratio statistic in logistic regression require accurate computation of the supremum of the likelihood function, particularly for outcomes in the sample space that represent completely-separated or quasi-completely-separated data sets. Current software does not always handle these cases well. Three simple solutions are proposed.     

Conditional Akaike information under covariate shift with application to small area estimation

In this study, we consider the problem of selecting explanatory variables of fixed effects in linear mixed models under covariate shift, which is when the values of covariates in the model for prediction differ from those in the model for observed data. We construct a variable selection criterion based on the conditional Akaike information introduced by Vaida & Blanchard (2005). We focus especially on covariate shift in small area estimation and demonstrate the usefulness of the proposed criterion. In addition, numerical performance is investigated through simulations, one of which is a design‐based simulation using a real dataset of land prices. The Canadian Journal of Statistics 46: 316–335; 2018 © 2018 Statistical Society of Canada     

Conditional specifications of multivariate pareto and student distributions

A random vector has a multivariate Pareto distribution if one of its univariate conditional distribution is Pareto and some of its marginals are identically distributed.A general method developed in the course of the proof of this result is applied also to characterize the multivariate Student (Cauchy) measure by one univariate Student conditional distribution.     

中国股票市场收益率的可预测性研究

构造了包括中国A股市场组合、行业组合、账面市值比组合和市值组合在内的31个投资组合,选取了8个预测因子(账面市值比、股利分配率、股息价格比、股息收益率、每股收益价格比、现金收益价格比、通货膨胀率、股票波动率),运用了可行拟广义最小二乘法对各因子对各投资组合收益率的可预测性进行了样本内和样本外检验.研究发现:1)中国股市收益率是可预测的,但是各投资组合收益率的可预测性在样本内、样本外、熊市和牛市均存在差异;2)绝大部分投资组合收益率的可预测性可由条件CAPM模型捕捉的时变系统风险溢价充分解释; 3)行业投资组合收益率的可预测性与行业集中度显著负相关,可由信息摩擦理论解释.