Development of the PEARLS model (Particulate Exposure from Ambient to Regional Lung by Subgroup) and use of Monte Carlo simulation to predict internal exposure to 2.5 in Toronto.

Air pollution is a current and growing concern for Canadians, and there is evidence that ambient levels that meet current exposure standards may be associated with mortality and morbidity in Toronto, Canada. Evaluating exposure is an important step in understanding the relationship between particulate matter (PM) exposure and health outcomes. This report describes the PEARLS model (Particulate Exposure from Ambient to Regional Lung by Subgroup), which predicts exposure distributions for 11 age-gender population subgroups in Toronto to PM2.5 (PM with a median aerodynamic diameter of 2.5 microm or less) using Monte Carlo simulation techniques. The model uses physiological and activity pattern characteristics of each subgroup to determine region-specific lung exposure to PM2.5, which is defined as the mass of PM2.5 deposited per unit time to each of five lung regions (two extrathoracic, bronchial, bronchiolar, and alveolar). The modeling results predict that children, toddlers, and infants have the broadest distributions of exposure, and the greatest chance of experiencing extreme exposures in the alveolar region of the lung. Importance analysis indicates that the most influential model variables are air exchange rate into indoor environments, time spent outdoors, and time spent at high activity levels. Additionally, a "critical point" was defined and introduced to the PEARLS to investigate the effects of possible threshold-pathogenic phenomena on subgroup exposure patterns. The analysis indicates that the subgroups initially predicted to be most highly exposed were likely to have the highest proportion of their population exposed above the critical point. Substantial exposures above the critical point were predicted in all subgroups for ambient concentrations of PM2.5 commonly observed in Toronto after continuous exposure of 24 hours or more.     

基带升余弦谱波形的数字实现及其分析

介绍了二进制横向滤波器(BTF)直接实现数据限带传输升余弦谱脉冲波形成形的方法。着重研究了影响横向滤波器结构的参数(每波特内取样数 K,单位冲激响应波形旁瓣数 L)与BTF 的阻带衰减和所形成升余弦谱信号在最坏情况下的码间干扰之间的关系,为优化工程设计提供了依据。最后给出了数值实例和实验结果。     

Spectral properties of the concurrent and forecasting seasonal linear filters of the X-11-ARIMA method

This study analyzes the properties of the linear filters of the X-11-ARIMA seasonal adjustment method applied for current seasonal adjustment. It provides the general formula for the combined weights that result from the ARIMA model extrapolation filters with the X-11 seasonal-adjustment filters. The three cases studied correspond to the three ARIMA models automatically tested by the X-11-ARIMA program, namely, (0, 1, 1)(0, 1, 1), (0, 2, 2)(0, 1, 1), and (2, 1. 2)(0, 1,1). The parameter values chosen reflect different degrees of flexibility of the trend-cycle and seasonal components. It is shown that the X-11-ARIMA linear filters for current seasonal adjustment are very flexible; they change with both the ARIMA extrapolation model and its parameter values, contrary to those of the X-11 program, which are fixed for a given set of options.     

Estimates of the Health Risk Reductions Associated with Attainment of Alternative Particulate Matter Standards in Two U.S. Cities

As part of its periodic re-evaluation of particulate matter (PM) standards, the U.S. Environmental Protection Agency estimated the health risk reductions associated with attainment of alternative PM standards in two locations in the United States with relatively complete air quality data: Philadelphia and Los Angeles. PM standards at the time of the analysis were defined for particles of aerodynamic diameter less than or equal to 10 microm, denoted as PM-10. The risk analyses estimated the risk reductions that would be associated with changing from attainment of the PM-10 standards then in place to attainment of alternative standards using an indicator measuring fine particles, defined as those particles of aerodynamic diameter less than or equal to 2.5 microm and denoted as PM-2.5. Annual average PM-2.5 standards of 12.5, 15, and 20 microg/m3 were considered in various combinations with daily PM-2.5 standards of 50 and 65 microg/m3. Attainment of a standard or set of standards was simulated by a proportional rollback of "as is" daily PM concentrations to daily PM concentrations that would just meet the standard(s). The predicted reductions in the incidence of health effects varied from zero, for those alternative standards already being met, to substantial reductions of over 88% of all PM-associated incidence (e.g., in mortality associated with long-term exposures in Los Angeles, under attainment of an annual standard of 12.5 microg/m3). Sensitivity analyses and integrated uncertainty analyses assessed the multiple-source uncertainty surrounding estimates of risk reduction.     

Air Pollution and Mortality: Quantification and Valuation of Years of Life Lost

To analyze the loss of life expectancy (LLE) due to air pollution and the associated social cost, a dynamic model was developed that took into account the decrease of risk after the termination of an exposure to pollution. A key parameter was the time constant for the decrease of risk, for which estimates from studies of smoking were used. A sensitivity analysis showed that the precise value of the time constant(s) was not critical for the resulting LLE. An interesting aspect of the model was that the relation between population total LLE and PM2.5 concentration was numerically almost indistinguishable from a straight line, even though the functional dependence was nonlinear. This essentially linear behavior implies that the detailed history of a change in concentration does not matter, except for the effects of discounting. This model was used to correct the data of the largest study of chronic mortality for variations in past exposure, performed by Pope et al. in 1995; the correction factor was shown to depend on assumptions about the relative toxicity of the components of PM2.5. In the European Union, an increment of 1 microg/m3 of PM2.5 for 1 year implies an average LLE of 0.22 days per person. With regard to the social cost of an air pollution pulse, it was found that for typical discount rates (3% to 8% real) the cost was reduced by a factor of about 0.4 to 0.6 relative to the case with zero discount rate, if the value of a life year was taken as given; if the value of a life year was calculated from the "value of statistical life" by assuming the latter as a series of discounted annual values, the cost varied by at most +/-20% relative to the case with zero discount rate. To assess the uncertainties, this study also examined how the LLE depended on the demographics (mortality and age pyramid) of a population, and how it would change if the relative risk varied with age, in the manner suggested by smoking studies. These points were found to have a relatively small effect (compared to the epidemiological uncertainties) on the calculated LLE.     

彩色图像脉冲噪声的自适应矢量滤波

提出了基于噪声像素检测的自适应矢量滤波器的新方法,该法对图像中噪声像素进行检测时,仅对噪声像素进行矢量滤波,而对非噪声像素则保持其原值不变,并可根据图像噪声情况自适应地选择滤波窗口。新滤波器能有效地滤除彩色随机脉冲噪声,并保持图像边缘与细节,其性能优于经典的矢量中值滤波器、方向一距离滤波器、方向一幅度矢量滤波器等非线性滤波器。     

SAR图像的边沿检测方法研究

针对合成孔径雷达（SAR）图像的特点,利用小波变换的高频分量能反映边沿细节的特性,提出了一种结合小波变换、中值滤波、自适应门限判决和微分梯度算子的边沿检测方法。实验结果表明,该方法具有良好的边沿检测效果和稳定性。     

一类混沌经济模型的控制方法的研究

就经济系统中的一类多参数混沌模型 ,应用微分动力学理论 ,研究了变参数结构反馈控制方法 ,成功地进行了多参数混沌控制 .并讨论小波滤波法 ,成功实现了混沌不稳定周期轨道的稳定控制方法 ,并以具体的财产管理混沌模型为例验证所提出的方法     

H公式与完全相关数对

定义完全相关数对并推导出求完全相关数对个数的H公式。     

Estimating Benchmark Exposure for Air Particulate Matter Using Latent Class Models

We performed benchmark exposure (BME) calculations for particulate matter when multiple dichotomous outcome variables are involved using latent class modeling techniques and generated separate results for both the extra risk and additional risk. The use of latent class models in this study is advantageous because it combined several outcomes into just two classes (namely, a high‐risk class and a low‐risk class) and compared these two classes to obtain the BME levels. This novel approach addresses a key problem in risk estimation—namely, the multiple comparisons problem, where separate regression models are fitted for each outcome variable and the reference exposure will rely on the results of the best‐fitting model. Because of the complex nature of the estimation process, the bootstrap approach was used to estimate the reference exposure level, thereby reducing uncertainty in the obtained values. The methodology developed in this article was applied to environmental data by identifying unmeasured class membership (e.g., morbidity vs. no morbidity class) among infants in utero using observed characteristics that included low birth weight, preterm birth, and small for gestational age.