Non uniform exponential bounds on normal approximation by Stein’s method and monotone size bias couplings

It is known that the normal approximation is applicable for sums of non negative random variables, W, with the commonly employed couplings. In this work, we use the Stein’s method to obtain a general theorem of non uniform exponential bound on normal approximation base on monotone size bias couplings of W. Applications of the main result to give the bound on normal approximation for binomial random variable, the number of bulbs on at the terminal time in the lightbulb process, and the number of m runs are also provided.     

Semi-doubly optimal concentric circles fitting with presence of heteroscedasticity

Previous studies focus on homogeneous and isotropic assumptions about the noisy data. Many methods have been developed recently for fitting concentric circles to data. In this paper, these statistical assumptions have been relaxed. To the best of our knowledge, only one iterative method has been recently developed. Due to its complexity, no such algorithm is available to compute the reliable maximum likelihood estimator (MLE). Accordingly, we have developed four new methods that outperform the existing methods including the orthogonal distance regression (ODR). We also discuss which of these methods is superior according to the four principles: statistical efficiency, accuracy, robustness, and computational efficiency. Numerical experiments on synthetic and real images have been conducted to validate our findings.     

Discovering hidden statistical issues through individual-level models in ecological studies

ABSTRACT

In ecological studies, individual inference is made based on results from ecological models. Interpretation of the results requires caution since ecological analysis on group level may not hold in the individual level within the groups, leading to ecological fallacy. Using an ecological regression example for analyzing voting behaviors, we highlight that the explicit use of individual-level models is crucial in understanding the results of ecological studies. In particular, we clarify three relevant statistical issues for each individual-level models: assessment of the uncertainty of parameter estimates obtained from a wrong model, the use of shrinkage estimation method for simultaneous estimation of many parameters, and the necessity of sensitivity analysis rather than adhering to one seemingly most compelling assumption.     

Enriching Surveys with Supplementary Data and its Application to Studying Wage Regression

We consider the problem of supplementing survey data with additional information from a population. The framework we use is very general; examples are missing data problems, measurement error models and combining data from multiple surveys. We do not require the survey data to be a simple random sample of the population of interest. The key assumption we make is that there exists a set of common variables between the survey and the supplementary data. Thus, the supplementary data serve the dual role of providing adjustments to the survey data for model consistencies and also enriching the survey data for improved efficiency. We propose a semi‐parametric approach using empirical likelihood to combine data from the two sources. The method possesses favourable large and moderate sample properties. We use the method to investigate wage regression using data from the National Longitudinal Survey of Youth Study.     

Left truncation in linked data: A practical guide to understanding left truncation and applying it using SAS and R

Time-to-event data such as time to death are broadly used in medical research and drug development to understand the efficacy of a therapeutic. For time-to-event data, right censoring (data only observed up to a certain point of time) is common and easy to recognize. Methods that use right censored data, such as the Kaplan–Meier estimator and the Cox proportional hazard model, are well established. Time-to-event data can also be left truncated, which arises when patients are excluded from the sample because their events occur before a specific milestone, potentially resulting in an immortal time bias. For example, in a study evaluating the association between biomarker status and overall survival, patients who did not live long enough to receive a genomic test were not observed in the study. Left truncation causes selection bias and often leads to an overestimate of survival time. In this tutorial, we used a nationwide electronic health record-derived de-identified database to demonstrate how to analyze left truncated and right censored data without bias using example code from SAS and R.     

A meta-analytic framework to adjust for bias in external control studies

While randomized controlled trials (RCTs) are the gold standard for estimating treatment effects in medical research, there is increasing use of and interest in using real-world data for drug development. One such use case is the construction of external control arms for evaluation of efficacy in single-arm trials, particularly in cases where randomization is either infeasible or unethical. However, it is well known that treated patients in non-randomized studies may not be comparable to control patients—on either measured or unmeasured variables—and that the underlying population differences between the two groups may result in biased treatment effect estimates as well as increased variability in estimation. To address these challenges for analyses of time-to-event outcomes, we developed a meta-analytic framework that uses historical reference studies to adjust a log hazard ratio estimate in a new external control study for its additional bias and variability. The set of historical studies is formed by constructing external control arms for historical RCTs, and a meta-analysis compares the trial controls to the external control arms. Importantly, a prospective external control study can be performed independently of the meta-analysis using standard causal inference techniques for observational data. We illustrate our approach with a simulation study and an empirical example based on reference studies for advanced non-small cell lung cancer. In our empirical analysis, external control patients had lower survival than trial controls (hazard ratio: 0.907), but our methodology is able to correct for this bias. An implementation of our approach is available in the R package ecmeta .     

No mood effects in the field: The case of car inspections

We study mood effect in the field to measure its economic impact and address shortcomings in the existing literature, which typically uses one single mood proxy and ignores selection effects. Using over 50 million car inspections in Sweden and England and multiple mood proxies, we study whether car inspectors are more lenient on good mood days and if car owners self-select into those days. We find evidence of a “Friday effect” in England and a small selection bias, but no support for consistent mood effect. Our findings highlight the importance of considering the expectations of rational actors who may exploit mood effect and the need to study mood in the field using different settings and multiple proxies to avoid hasty conclusions.     

A network centrality bias: Central individuals in workplace networks have more supportive coworkers

Combining the results of two empirical studies, we investigate the role of alters’ motivation in explaining change in ego’s network position over time. People high in communal motives, who are prone to supportive and altruistic behavior in their interactions with others as a way to gain social acceptance, prefer to establish ties with co-workers occupying central positions in organizational social networks. This effect results in a systematic network centrality bias: The personal network of central individuals (individuals with many incoming ties from colleagues) is more likely to contain more supportive and altruistic people than the personal network of individuals who are less central (individuals with fewer incoming ties). This result opens the door to the possibility that the effects of centrality so frequently documented in empirical studies may be due, at least in part, to characteristics of the alters in an ego’s personal community, rather than to egos themselves. Our findings invite further empirical research on how alters’ motives affect the returns that people can reap from their personal networks in organizations.     

Early socialization of hostile attribution bias: The roles of parental attributions,parental discipline,and child attributes

The goal of this study was to examine child and parent predictors of children's hostile attribution bias (HAB) with a particular focus on exploring the associations between parents’ early attribution of child misbehavior and children's HAB in the transition to school age. Participants were 241 children (118 girls) of middle‐income families who were at risk for school‐age conduct problems. Multi‐method, multi‐informant data were collected on maternal attributions of child misbehavior, parental use of corporal punishment, and child attributes (i.e., verbal IQ, effortful control, theory of mind, and emotional understanding) at 3 years, and child HAB in ambiguous situations at 6 years. Results indicated that mothers’ internal explanations for children's misconduct may either reduce or increase children's later HAB depending on the specific content of attributions, such that mothers’ belief that children misbehave because of their internal state (i.e., emotional state or temperament) was associated with lower levels of child HAB, whereas attributing power‐based motives (i.e., manipulative, controlling intentions) in children was associated with higher levels of HAB. The findings are discussed with respect to appreciating the complexity of parents’ explanations for children's behavior, and considering parental cognition as a potential target for early identification and prevention of child HAB and related problems.     

Changes in anti-fat weight bias in women after exposure to thin and plus-sized models

We examined whether exposing women to female models with different body sizes lead to changes in weight-based attitudes and whether evaluation focus altered the effects. Female college students (N = 214) were exposed to 22 images of either thin or overweight models. Participants rated models on either appearance or non-appearance characteristics and completed measures of anti-fat attitudes, thin ideal internalization, and demographics. Participants rated thin and overweight models equally attractive and sexy. Viewing overweight models showed a significant reduction in anti-fat attitudes. There were no effects for thin models or evaluation ratings. Discussion focuses on the implications of positive images of overweight individuals on social attitudes.