东北农业大学生物技术专业建设历史与发展成效

生物技术是21世纪一门高新技术改造、整合提升的交叉性、综合性很强的新兴学科。我校是开设生物技术专业较早的农业院校之一。20年来,该专业在"理农结合、学科交叉、加强基础、重视创新"的办学理念的指导下不断壮大,为国家培养了大批优秀人才。文章总结了我校生物技术专业的建设历史与发展成果,为发展品牌专业建设提供了思路和范例。     

Hazard functions and life distributions in discrete time

The problem of studying lifelength distributions in discrete time is considered for certain forms of hazard functions. A class of life distributions that consists of the geometric, the Waring and the negative hypergeometric distributions is shown to result when the hazard function is inversely proportional to some linear function of time.     

An Empirical Approach to Sufficient Similarity: Combining Exposure Data and Mixtures Toxicology Data

When assessing risks posed by environmental chemical mixtures, whole mixture approaches are preferred to component approaches. When toxicological data on whole mixtures as they occur in the environment are not available, Environmental Protection Agency guidance states that toxicity data from a mixture considered “sufficiently similar” to the environmental mixture can serve as a surrogate. We propose a novel method to examine whether mixtures are sufficiently similar, when exposure data and mixture toxicity study data from at least one representative mixture are available. We define sufficient similarity using equivalence testing methodology comparing the distance between benchmark dose estimates for mixtures in both data‐rich and data‐poor cases. We construct a “similar mixtures risk indicator”(SMRI) (analogous to the hazard index) on sufficiently similar mixtures linking exposure data with mixtures toxicology data. The methods are illustrated using pyrethroid mixtures occurrence data collected in child care centers (CCC) and dose‐response data examining acute neurobehavioral effects of pyrethroid mixtures in rats. Our method shows that the mixtures from 90% of the CCCs were sufficiently similar to the dose‐response study mixture. Using exposure estimates for a hypothetical child, the 95th percentile of the (weighted) SMRI for these sufficiently similar mixtures was 0.20 (i.e., where SMRI <1, less concern; >1, more concern).     

An additive subdistribution hazard model for competing risks data

The cumulative incidence function plays an important role in assessing its treatment and covariate effects with competing risks data. In this article, we consider an additive hazard model allowing the time-varying covariate effects for the subdistribution and propose the weighted estimating equation under the covariate-dependent censoring by fitting the Cox-type hazard model for the censoring distribution. When there exists some association between the censoring time and the covariates, the proposed coefficients’ estimations are unbiased and the large-sample properties are established. The finite-sample properties of the proposed estimators are examined in the simulation study. The proposed Cox-weighted method is applied to a competing risks dataset from a Hodgkin's disease study.     

论教师教育专业大学生多媒体应用能力的培养

本文探讨了培养普通高校教师教育专业学生（以下简称教师教育专业学生）多媒体应用能力的方法，探索了培养大学生多媒体应用能力的教学方法。     

适应新形势，实现新要求——合肥工业大学非英语专业博士生英语教改与实践

针对合肥工业大学非英语专业博士生教学时数大幅度减少的现状，提出博士生英语教学应以国际学术交流英语为中心，并展开博士生英语教学改革尝试及实效性研究，以期促进博士生使用英语进行国际学术交流，从而实现其科研创新能力不断提升的教学基本目标。     

Application of FISK,an Invasiveness Screening Tool for Non‐Native Freshwater Fishes,in the Murray‐Darling Basin (Southeastern Australia)

The Fish Invasiveness Scoring Kit (FISK) is currently one of the most popular pre‐screening tools for freshwater fishes. A recent upgrade has ensured its wider climatic relevance to countries with subtropical regions. This enhancement is of particular importance to Australia, which encompasses tropical, arid, and temperate zones, and where the introduction of non‐native fish species poses a significant risk to biodiversity. In this study, 55 fish species previously evaluated in a U.K.‐based calibration of FISK are reassessed for their potential invasiveness in the Murray‐Darling Basin (MDB; southeastern Australia), the continent's largest catchment encompassing arid and temperate climates. Approximately half of the species were classed as “medium risk” and the other half as “high risk,” and the ≥19 threshold previously identified from the calibration study was confirmed. The three highest scoring species (common carp Cyprinus carpio carpio, goldfish Carassius auratus, and eastern mosquitofish Gambusia holbrooki) were those already present and invasive in the area, whereas nearly half of the tropical and subtropical species had lower scores compared to U.K. assessments, possibly because of climate change predictions of drier conditions across the MDB. There were some discordances between FISK and two Australian‐based assessment protocols, one of which is qualitative and the other represents a simplified version of FISK. Notably, the Australian origins of FISK should provide for an additional reason for further applications of the tool in other RA areas (i.e., drainage basins) of the continent, ultimately encouraging adoption as the country's reference screening tool for management and conservation purposes.     

Effectiveness of FISK,an Invasiveness Screening Tool for Non‐Native Freshwater Fishes,to Perform Risk Identification Assessments in the Iberian Peninsula

Risk assessments are crucial for identifying and mitigating impacts from biological invasions. The Fish Invasiveness Scoring Kit (FISK) is a risk identification (screening) tool for freshwater fishes consisting of two subject areas: biogeography/history and biology/ecology. According to the outcomes, species can be classified under particular risk categories. The aim of this study was to apply FISK to the Iberian Peninsula, a Mediterranean climate region highly important for freshwater fish conservation due to a high level of endemism. In total, 89 fish species were assessed by three independent assessors. Results from receiver operating characteristic analysis showed that FISK can discriminate reliably between noninvasive and invasive fishes for Iberia, with a threshold of 20.25, similar to those obtained in several regions around the world. Based on mean scores, no species was categorized as “low risk,” 50 species as “medium risk,” 17 as “moderately high risk,” 11 as “high risk,” and 11 as “very high risk.” The highest scoring species was goldfish Carassius auratus. Mean certainty in response was above the category “mostly certain,” ranging from tinfoil barb Barbonymus schwanenfeldii with the lowest certainty to eastern mosquitofish Gambusia holbrooki with the highest level. Pair‐wise comparison showed significant differences between one assessor and the other two on mean certainty, with these two assessors showing a high coincidence rate for the species categorization. Overall, the results suggest that FISK is a useful and viable tool for assessing risks posed by non‐native fish in the Iberian Peninsula and contributes to a “watch list” in this region.     

重点突破:中国媒体国际传播的战略选择

国际传播能力建设怎样才能取得实际效果?国家和媒体的投入怎样才能实现效益最大化?数据对比发现,中国媒体在经济实力、人力资源数量和结构等方面与西方大型传媒集团存在较大差距,无法与之全面抗衡,宜实施重点突破战略。所谓重点突破战略,就是要对传播内容、传播渠道、传播对象等进行精心选择,将有限的资源优先用于能最有效地影响国际舆论的方面,最大限度地提升国际传播的效率和效果。在深入调研的基础上,本文对中国媒体国际传播的突破重点和突破方法分别提出了若干建议。