基于知识链的管理

论述了知识链的有关概念和特点,通过分析以往的知识链模型,提出了改进的知识链模型;对知识链管理的机制进行了分析;从控制论的角度,对知识链内部知识成长的机制进行了分析,并指出知识链内部知识转移的影响因素,为知识管理的发展提供了一定的理论依据。     

Geometric Method and Generalized Linear Models. Two Opposite Multiparametric Approaches Illustrated on a Sample of Pituitary Adenomas

We used two statistical methods to identify prognostic factors: a log-linear model (logistic and COX regression, based on the notions of linearity and multiplicative relative risk), and the CORICO method (ICOnography of CORrelations) based on the geometric significance of the correlation coefficient. We applied the methods to two different situations (a "case-control study' and a "historical cohort'). We show that the geometric exploratory tool is particularly suited to the analysis of small samples with a large number of variables. It could save time when setting up new study protocols. In this instance, the geometric approach highlighted, without preconceived ideas, the potential role of multihormonality in the course of pituitary adenoma and the unexpected influence of the date of tumour excision on the risk attached to haemorrhage.     

司空图《诗品》篇天人合一思维模式的原型追溯

以原型的方法对司空图《诗品》天人合一思维模式进行了全面分析。指出司空图《诗品》的思维模式遵循了中国古代由诗歌品阶、天时、时律、时历等形成的系统的天人合一模式，是典型的中国思维。     

素质拓展探索——建立数学教学新模式

本文简述建立数学教学新模式的必要性;论述了知识、能力、品质、方法之间的辨证关 系;提出了“知识、能力、品质”相结合的教学模式和一定的方法。     

Statistical Analyses and Modelling of the Mixing Process of Euro Coins in Germany and Europe

This paper reports on the mixing of Euro coins from different countries of origin in Europe, which started on 1 January 2002. There is an interesting conclusion: that the mobility of small and large denominations is different. The long‐term behaviour of the mixing process is studied using a simple deterministic model and data from Germany, France and the Netherlands. The analysis leads to predictions about the future progress of the mixing process.     

美国期刊业对我国期刊的启示

美国期刊业的基本特征可以归纳为:(1)集团化规模庞大;(2)塑造品牌,建立核心竞争力;(3)高度重视人力资源;(4)发行量决定广告收入。针对我国期刊业的现状与不足,通过中美两国期刊的比较研究,指出我国期刊在新形势下快速发展应借鉴之处和应对之策。     

高师技法课改革的专业特殊性与科学性

本文从高师技法课(声乐、钢琴)教学改革的大潮中,提出了教学改革中应注意专业的特殊性和科学性,阐述了教学改革应遵循的基本原则以及合理的课型模式。     

Estimation of Metabolic Rate Constants in PBPK‐Models from Liver Slice Experiments: What Are the Experimental Needs?

A mechanistic model is presented describing the clearance of a compound in a precision-cut liver slice that is incubated in a culture medium. The problem of estimating metabolic rate constants in PBPK models from liver slice experiments is discussed using identifiability analysis. From the identifiability problem analysis, it appears that in addition to the clearance, the compound's free fraction in the slice and the diffusion rate of the exchange of the compound between culture medium and liver slice should be identified. In addition, knowledge of the culture medium volume, the slice volume, the compound's free fraction, and octanol-water-based partition between medium and slice is presupposed. The formal solution for identification is discussed from the perspective of experimental practice. A formally necessary condition for identification is the sampling of parent compound in liver slice or culture medium. However, due to experimental limitations and errors, sampling the parent compound in the slice together with additional sampling of metabolite pooled from the medium and the slice is required for identification in practice. Moreover, it appears that identification results are unreliable when the value of the intrinsic clearance exceeds the value of the diffusion coefficient, a condition to be verified a posteriori.     

论企业经营管理与专利技术的关系

本文认为随着我国社会主义市场经济体制的建立和完善 ,尤其是加入WTO以后专利战略、专利信息的获取与利用、专利权营销等已成为企业经营管理的重要内容和手段。并探讨了企业经营管理的各个方面与专利技术的关系。     

加入WTO后我国证券业的应对策略

加入WTO后 ,将给我国证券业带来前所未有的机遇和挑战。WTO对我国证券市场提出了更加开放的要求 ,我国应循序渐进地推进证券市场的对外开放 ,大力培育机构投资者 ,推进资本市场多元化 ,促进证券业发展壮大。