Overcoming the ‘tyranny of the urgent’: integrating gender into disease outbreak preparedness and response

ABSTRACT

This article contributes to discussions on the gender dimensions of disease outbreaks, and preparedness policies and responses, by providing a multi-level analysis of gender-related gaps, particularly illustrating how the failure to challenge gender assumptions and incorporate gender as a priority at the global level has national and local impacts. The implications of neglecting gender dynamics, as well as the potential of equity-based approaches to disease outbreak responses, is illustrated through a case study of the Social Enterprise Network for Development (SEND) Sierra Leone, a non-government organisation (NGO) based in Kailahun, during the Ebola outbreak.     

Evaluation of Inhaled Versus Deposited Dose Using the Exponential Dose‐Response Model for Inhalational Anthrax in Nonhuman Primate,Rabbit, and Guinea Pig

The application of the exponential model is extended by the inclusion of new nonhuman primate (NHP), rabbit, and guinea pig dose‐lethality data for inhalation anthrax. Because deposition is a critical step in the initiation of inhalation anthrax, inhaled doses may not provide the most accurate cross‐species comparison. For this reason, species‐specific deposition factors were derived to translate inhaled dose to deposited dose. Four NHP, three rabbit, and two guinea pig data sets were utilized. Results from species‐specific pooling analysis suggested all four NHP data sets could be pooled into a single NHP data set, which was also true for the rabbit and guinea pig data sets. The three species‐specific pooled data sets could not be combined into a single generic mammalian data set. For inhaled dose, NHPs were the most sensitive (relative lowest LD₅₀) species and rabbits the least. Improved inhaled LD₅₀s proposed for use in risk assessment are 50,600, 102,600, and 70,800 inhaled spores for NHP, rabbit, and guinea pig, respectively. Lung deposition factors were estimated for each species using published deposition data from Bacillus spore exposures, particle deposition studies, and computer modeling. Deposition was estimated at 22%, 9%, and 30% of the inhaled dose for NHP, rabbit, and guinea pig, respectively. When the inhaled dose was adjusted to reflect deposited dose, the rabbit animal model appears the most sensitive with the guinea pig the least sensitive species.     

A monte carlo evaluation of response surface analysis based on paired-comparison data

The use of the logit transformation on paired-comparison data in the weighted least squares analysis of response surfaces for aesthetic qualities of products is discussed. Monte Carlo simulations are employed to investigate the small sample properties of the estimators and test statistics. A secondary objective of the Monte Carlo simulations is the comparison of two transformation procedures. The simulations are of standard-item paired-compar-ison experiments in which ties are not allowed.     

New Data,Strategies, and Insights for Listeria monocytogenes Dose‐Response Models: Summary of an Interagency Workshop, 2011

Listeria monocytogenes is a leading cause of hospitalization, fetal loss, and death due to foodborne illnesses in the United States. A quantitative assessment of the relative risk of listeriosis associated with the consumption of 23 selected categories of ready‐to‐eat foods, published by the U.S. Department of Health and Human Services and the U.S. Department of Agriculture in 2003, has been instrumental in identifying the food products and practices that pose the greatest listeriosis risk and has guided the evaluation of potential intervention strategies. Dose‐response models, which quantify the relationship between an exposure dose and the probability of adverse health outcomes, were essential components of the risk assessment. However, because of data gaps and limitations in the available data and modeling approaches, considerable uncertainty existed. Since publication of the risk assessment, new data have become available for modeling L. monocytogenes dose‐response. At the same time, recent advances in the understanding of L. monocytogenes pathophysiology and strain diversity have warranted a critical reevaluation of the published dose‐response models. To discuss strategies for modeling L. monocytogenes dose‐response, the Interagency Risk Assessment Consortium (IRAC) and the Joint Institute for Food Safety and Applied Nutrition (JIFSAN) held a scientific workshop in 2011 (details available at http://foodrisk.org/irac/events/ ). The main findings of the workshop and the most current and relevant data identified during the workshop are summarized and presented in the context of L. monocytogenes dose‐response. This article also discusses new insights on dose‐response modeling for L. monocytogenes and research opportunities to meet future needs.     

Plans for blocking and fractions of nested cube designs

Plans for implementing nested cube designs invoiving 3 to 5 factors within moderate sized blocks are eveloped. Fractionsc of 1/2 and 1/4 replicates of components of the generic design are used. Suggestions for data analysis are offered.     

Determinants of consistent,timely, and active responses in corporate crises

This paper investigates the individual and combined factors affecting the extent to which corporations respond to crisis events consistently, in a timely manner, and actively. The determinants examined include public relations autonomy, legal dominance, strategic orientation, and organizational factors. A survey was conducted of communications mangers, public affairs personnel, and public relations personnel, drawn from the top 500 companies operating in Taiwan. Results indicate that the relative effect of individual sources of influence on crisis response is greatest for situations in which public relations departments have the most autonomy, followed by those where crisis management is handled with a strategic orientation, those where the legal departments dominate, and those where organizational factors provide the main avenue of address. The results emphasize the intriguing role of public relations autonomy by demonstrating its significant impact on providing a consistent, timely, and active crisis response. The strategic orientation of situation analysis also predicts a consistent response, whereas legal dominance predicts strategic ambiguity or inconsistent communication.     

Computer-Supported Distance Art Therapy: A Focus on Traumatic Illness

SUMMARY

Recent research has documented the growing gap between those who have access to information technology and those who do not. Reviewing available literature regarding the lack of access to computers and technology by oppressed groups, this paper discusses problems inherent in ignoring this issue in social work education and practice. Finally, some of the promising interventions currently used to address problems of access are outlined and recommendations for social workers are highlighted.     

Intimate Violence in Lesbian Relationships

This paper describes the findings of a survey of 1109 lesbians who attended the Women's Music Festival held in Michigan in carly August 1985. The primary objectives of the study were to document the incidence of domestic violence in a non-random sample of lesbian relationships; to identify and describe the types of domestic violence experienced and/or perpetrated; and to ascertain thc availability and accessibility of community helping resources to survivors and perpetrators after an abusive episode. Comparisons with domestic violence in heterosexual relationships are also made, followed by a discussion on the research and practice implications of the findings.     

环境法“义务重心”的理论证成与立法回应

环境法“义务重心论”是从“法的技术”层面提出的观点,是有别于“法的价值”层面而言的“义务本位论”,既非漠视主体的权利,也非“义务本位论”的回归,而是对环境权利“最给力”的捍卫与落实,其实践意义在于增进法律实效.环境法“义务重心”的客观依据正是自然规律的客观性、人类需要的基础性以及环境问题的特殊性.中国环境法亟需实现从“亡羊补牢式”“倒逼”到“未雨绸缪式 ”“预见”的“义务重心”立法理念匹配以及在合理配置各主体环境义务、扩充环境积极义务的内容、增加环境义务的履行方式以及强化违反环境义务的法律后果等层面进行环境立法“义务重心”的路径拓展,以期通过“义务重心”的环境立法变革增进环境法的实效.     

论食品安全事件中的良性媒体应对

食品安全事件是近年来全球公共安全问题中的热点,由于食品安全的重要性、食品安全事件的公众效应以及基于传媒的属性,媒体常将其作为关注的热点。媒体在食品安全事件中发挥着监测预警、沟通信息、舆论引导等功能,同时也存在关注视角的选择性和职业自律的松懈等不足。作为一种社会公共资源和社会监督力量,基于传媒良知和职业操守,媒体在食品安全事件中必须形成一套良性的应对机制,包括建立信息有效传播机制、建立食品安全事件相关方的沟通协调机制、建立媒体自律机制等。