Adults with Down Syndrome and Alzheimer's Disease

Abstract

An increasing number of people with Down syndrome are at risk of dementia resulting from Alzheimer's disease. Many reside in community group homes. When they are affected by dementia, the challenge to agencies providing group homes is how to best provide continued housing and provide effective dementia-related care management. In the general population, long term care is typically provided in nursing facilities, often in special care units (SCUs). This study evaluated select factors found in group homes and SCUs to determine which is able to provide a better quality of life for people with Down syndrome affected by dementia. Interviews, using quality of life indicators, were conducted at 20 sites, equally selected from group homes and SCUs, on the basis of their experience with people with dementia. Results indicate that group homes can provide conditions associated with better quality of life and, additionally, operate with lower staffing costs due to the non-utilization of medical staff.     

Intergenerational-Multigenerational Relationships

Abstract

Multigenerational and intergenerational relations are used interchangeably by the United Nations in official documents. However, the terms are not universally considered synonymous. This article explores the origin of terminology usage and how these terms are used differentially in the literature on intergenerational relationships. It also places the discussion within a global framework by linking it to the United Nations Second World Assembly on Ageing and the International Plan of Action on Ageing Madrid 2002.     

Building Strength Through Challenging Homophobia: Liberation Workshops with Younger and Midlife Irish Lesbians

Drawing on the theoretical framework of liberation psychology, this article details workshops on liberation psychology conducted in Ireland with lesbian and transgendered persons aged from early 20's to late 50's. Both younger and older lesbians in the workshops benefited from the opportunity to focus on oppression and to explore options for transformation. The workshops illustrated many of the strengths and vulnerabilities associated with living with homophobia and demonstrated the value of action and engagement. Midlife lesbians were more aware of the systemic nature of homophobia and of the negative emotions related to that. They saw many of these as understandable and even necessary reactions to oppression rather than as negative patterns. These older lesbians tended to be more accepting of the course their lives had taken and of the ways in which choices had been influenced by homophobia and heterosexism. They tended to be more relativistic in their views on coming out, viewing coming out as a decision for each context rather than an overall principle. They valued the importance of community and of activism, and though they were aware of some of the challenges, they also had more positive experiences in this area. These strengths can facilitate managing both homophobia and aging more effectively.     

Retirement Villages

No abstract available for this article.     

主动形式表被动意义的语表及语义分析

在英语中,被动意义除了最常用的“be+V—ed”结构之外,有时也可以采用主动形式来表示,只不过句子的语义功能则由原来强调动作的承受者变为强调人或事物处于某种静止状态之中。本文初步探讨了这些主动形式的语法结构及语义特征。     

论“主动性学习”在大学英语教学中的重要性

"主动性学习"在大学英语教学中起着非常重要的作用.它不同于传统的英语教学方法,传统的英语镲教学在运用语言进行交流方面有其局限性.计算机教学手段能解决传统的英语教学法中的许多问题.在本文中着重强调了如何激励学生进行"主动性学习".     

养老与收养——论我国步入老年型社会后收养制度的完善

探讨了收养的法律性质及目的等问题,在指出收养法律性质的"公法化"趋势以及收养目的的变迁所显示的收养制度适应性的基础上,结合我国开始步入老年型社会的国情,建议我国收养法将"养老"增设为立法目的,进而提出放宽成年人收养条件,增设不完全收养及撤销制度,确立配偶的收养同意权等立法构想.     

Detection of interactions in experiments on large numbers of factors

One of the main advantages of factorial experiments is the information that they can offer on interactions. When there are many factors to be studied, some or all of this information is often sacrificed to keep the size of an experiment economically feasible. Two strategies for group screening are presented for a large number of factors, over two stages of experimentation, with particular emphasis on the detection of interactions. One approach estimates only main effects at the first stage (classical group screening), whereas the other new method (interaction group screening) estimates both main effects and key two-factor interactions at the first stage. Three criteria are used to guide the choice of screening technique, and also the size of the groups of factors for study in the first-stage experiment. The criteria seek to minimize the expected total number of observations in the experiment, the probability that the size of the experiment exceeds a prespecified target and the proportion of active individual factorial effects which are not detected. To implement these criteria, results are derived on the relationship between the grouped and individual factorial effects, and the probability distributions of the numbers of grouped factors whose main effects or interactions are declared active at the first stage. Examples are used to illustrate the methodology, and some issues and open questions for the practical implementation of the results are discussed.     

Alterations in IGF-I affect elderly: role of physical activity

The growth hormone–insulin-like growth factor I (IGF-I) axis is an important physiological regulator muscle for development. Although there is evidence that aging muscle retains the ability to synthesize IGF-I, there is also evidence that aging may be associated with attenuation of the ability of exercise to induce an isoform of IGF-I that promotes satellite cell proliferation. However, it is clear that overexpression of IGF-I in the muscle can protect against age-related sarcopenia. Strength training appears to be the intervention of choice for the prevention and treatment of sarcopenia. IGF-I has been implicated in the loss of the muscle with age, and IGF-I expression levels change as a consequence of strength training in older adults. However, it seems that advancing age, rather than declining serum levels of IGF-I, appears to be a major determinant of life-time changes in body composition in women and men. We concluded that resistive exercise is a significant determinant of muscle mass and function. Elevated levels of IGF-I have been found in physically active compared to sedentary individuals. Recent work suggests that IGF-I as a mediator plays an important role in muscle hypertrophy and angiogenesis, both of which characterize the anabolic adaptation of muscles to exercise.     

Coming of age

Those of us who study aging have the unique opportunity to live their subject matter. Whether we learn any personal lessons is a matter of our own reflectivity, but personal experience can make us far better scholars than can scholarship alone. As one ponders the life course, it is clear that a number of institutional influences, temporal patterning, and unexpected intervening variables are involved in the unfolding of one's life. Life-long institutional memberships furnish social capital that helps establish parameters for our personal experience, for how we view our personal trajectories and for our ability to cope with the aging process itself. But how to come to terms with unexpected occurrences that alter the anticipated futures we had in mind? Do our scholarly efforts and our experience come together in ways that enrich one or the other? These are the questions I explore in this personal essay.