高铜对育肥猪生产效果的影响

将30头30±2kg的育肥猪(长白×内江)随机分成试验组和对照组。对照组采用个体户原用添加剂,试验组采用自配高铜添加剂。结果表明:对照组日增重341.67g,料肉比4.0:1试验组日增重364.67g,料肉比3.7:1。两组日增重差异显著(P<0.05)。     

利用数控增益放大器提高A/D转换器的分辨率

文章介绍利用数控增益放大器LH0086大幅度提高A／D转换器分辨率的方法,可将8位A／D转换器的分辨率提高到接近16位A／D的水平,适用于高速数据系采集系统,给出了相应的硬件原理图和软件框图。     

基于模糊判断矩阵信息确定专家权重的方法

本文对群组模糊判断矩阵集结过程中确定专家权重的问题进行了研究,建立了模糊判断矩阵的特征矩阵和求解群集结矩阵的最优化模型,通过矩阵之间距离度量判断信息自身逻辑一致性程度和群体相容性程度,给出一种基于专家判断信息的可信度计算其后验权重的方法,最后用算例予以说明.     

基于灰关联约束超效率DEA的重点实验室评估研究——以河北省省级重点实验室为例

目前国内外对重点实验室的评估主要采用专家评价等软评价方法,较少考虑科技投入和科技产出之间的关联关系。在对国内外重点实验室评估方法进行深入研究的基础上,利用灰色关联度分析指标内在的关联性,将其作为限制条件加入超效率DEA评价模型中,构建了基于灰色关联权重约束的超效率DEA评价模型,并应用于河北省省级重点实验室评估的实证分析。研究结果显示,此模型与传统的CCR模型和超效率DEA模型相比,既可以揭示科技投入和科技产出之间的内在联系,又可以保持DEA评价的客观性,与此同时,还可实现不同实验室评估结果的全排序,使得评估结果更加符合实际。     

学前儿童基于重量和声音进行因果推理的发展研究

儿童的推理能力历来都是考察儿童认知发展的重点。本研究探讨了在多种属性刺激下3~5岁儿童基于重量和声音进行 因果推理的表现。结果发现：4岁和5岁儿童选择正确目标物的准确率显著高于3岁儿童；和同时使用声音与重量判断目标物相 比，儿童在单独使用重量或声音的情况下更容易区分目标物。总之，儿童因果推理能力发展的关键期在4岁并且当任务难度较高 的情况下其因果机制极易受到干扰。     

Differences in meconium stained amniotic fluid in an Australian population: A retrospective study

Background

Meconium stained amniotic fluid commonly occurs postdates (?>40 weeks gestation) indicating fetal maturity. Previous literature indicates that different ethnicities mature at different rates.

Improving Weight of Evidence Approaches to Chemical Evaluations

Federal and other regulatory agencies often use or claim to use a weight of evidence (WoE) approach in chemical evaluation. Their approaches to the use of WoE, however, differ significantly, rely heavily on subjective professional judgment, and merit improvement. We review uses of WoE approaches in key articles in the peer‐reviewed scientific literature, and find significant variations. We find that a hypothesis‐based WoE approach, developed by Lorenz Rhomberg et al., can provide a stronger scientific basis for chemical assessment while improving transparency and preserving the appropriate scope of professional judgment. Their approach, while still evolving, relies on the explicit specification of the hypothesized basis for using the information at hand to infer the ability of an agent to cause human health impacts or, more broadly, affect other endpoints of concern. We describe and endorse such a hypothesis‐based WoE approach to chemical evaluation.     

Bayesian adaptive dose‐escalation designs for simultaneously estimating the optimal and maximum safe dose based on safety and efficacy

The main purpose of dose‐escalation trials is to identify the dose(s) that is/are safe and efficacious for further investigations in later studies. In this paper, we introduce dose‐escalation designs that incorporate both the dose‐limiting events and dose‐limiting toxicities (DLTs) and indicative responses of efficacy into the procedure. A flexible nonparametric model is used for modelling the continuous efficacy responses while a logistic model is used for the binary DLTs. Escalation decisions are based on the combination of the probabilities of DLTs and expected efficacy through a gain function. On the basis of this setup, we then introduce 2 types of Bayesian adaptive dose‐escalation strategies. The first type of procedures, called “single objective,” aims to identify and recommend a single dose, either the maximum tolerated dose, the highest dose that is considered as safe, or the optimal dose, a safe dose that gives optimum benefit risk. The second type, called “dual objective,” aims to jointly estimate both the maximum tolerated dose and the optimal dose accurately. The recommended doses obtained under these dose‐escalation procedures provide information about the safety and efficacy profile of the novel drug to facilitate later studies. We evaluate different strategies via simulations based on an example constructed from a real trial on patients with type 2 diabetes, and the use of stopping rules is assessed. We find that the nonparametric model estimates the efficacy responses well for different underlying true shapes. The dual‐objective designs give better results in terms of identifying the 2 real target doses compared to the single‐objective designs.     

局部均衡函数及其构造

研究了局部均衡函数,定义了改进的局部变权向量,提出了与之对应的状态局部变权向量和局部均衡函数,证明了两类函数是局部均衡函数;利用局部变权向量建立了企业信用评估模型,并通过实例说明了该理论是有效的和合理的.     

结构优化对我国农产品出口竞争力的影响

应用产业组织理论,揭示结构优化对农产品国际竞争力的作用机理。以RCA衡量农产品出口竞争力并建立多元回归模型,在有效分离工资、土地灌溉面积和汇率等因素后,实证研究发现技术结构对农产品出口竞争力有显著正向影响。当前经济背景下,提升农产品出口竞争力的政策思路,需从传统的要素禀赋优势转移到结构优化的轨道上来。优化农产品出口结构,政府需加大对高附加值农产品在生产、流通、出口等环节的支持力度,营造寡占的农产品市场结构,鼓励和扶持创意农业的发展。