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481.
In this paper, a model is set forth relating (a) overall life satisfaction of children to children’s values and (b) children’s values to parents’ values. Using confirmatory factor analysis models three dimensions of values (materialistic values, capacities and knowledge values and interpersonal relationship values) consistently emerged in 5 countries (Brazil, South Africa, Norway, Spain and India) for both parents and children. There was a considerable amount of missing data, mainly because the parent’s questionnaire was often not returned. Full information maximum likelihood estimators with missing data were thus used.Multiple-group analyses were next performed to assess factor invariance of the three value dimensions across the five countries for both parents and children. This implies testing the equality of factor loadings and intercepts across groups. This equality is required to ensure that factors have the same interpretation in all groups, which is necessary when comparing any aspect of the factor distribution across groups.The only two countries for which the interpretation of value dimensions was invariant for both parents and children were Brazil and Spain. The results of other countries could thus not be compared. Multiple-group structural equation models revealed that both parents and children scored higher on most values in Brazil than in Spain. In both countries, each child value dimension was only significantly predicted by the same value dimension of the parents. R-squares were in the 4–12% range and slightly higher in Brazil. The only value dimension that had some effect on overall life satisfaction was capacities and knowledge, which was so in both countries.Acknowledgements are due to the country project directors and their associates Per Egil Mjaavatn (Norwegian University of Science and Technology, Trondheim, Norway), Usha Nayar (Tata Institute of Social Sciences, India), Irene Rizzini (Pontifícia Universidade Católica do Rio de Janeiro, Brazil), Rose September (Western Cape University, South Africa) and Ferran Casas (Catalan Network of Child Researchers – XCIII – in co-operation with the University of Girona, Spain) for permitting us to use part of their project and to Childwatch International, Oslo, for sponsorship.  相似文献   
482.
We call a sample design that allows for different patterns, or sets, of data items to be collected from different sample units a Split Questionnaire Design (SQD). SQDs can be thought of as incorporating missing data into survey design. This paper examines the situation where data that are not collected by an SQD can be treated as Missing Completely At Random or Missing At Random, targets are regression coefficients in a generalised linear model fitted to binary variables, and targets are estimated using Maximum Likelihood. A key finding is that it can be easy to measure the relative contribution of a respondent to the accuracy of estimated model parameters before collecting all the respondent's model covariates. We show empirically and theoretically that we could achieve a significant reduction in respondent burden with a negligible impact on the accuracy of estimates by not collecting model covariates from respondents who we identify as contributing little to the accuracy of estimates. We discuss the general implications for SQDs.  相似文献   
483.
Missing covariates data is a common issue in generalized linear models (GLMs). A model-based procedure arising from properly specifying joint models for both the partially observed covariates and the corresponding missing indicator variables represents a sound and flexible methodology, which lends itself to maximum likelihood estimation as the likelihood function is available in computable form. In this paper, a novel model-based methodology is proposed for the regression analysis of GLMs when the partially observed covariates are categorical. Pair-copula constructions are used as graphical tools in order to facilitate the specification of the high-dimensional probability distributions of the underlying missingness components. The model parameters are estimated by maximizing the weighted log-likelihood function by using an EM algorithm. In order to compare the performance of the proposed methodology with other well-established approaches, which include complete-cases and multiple imputation, several simulation experiments of Binomial, Poisson and Normal regressions are carried out under both missing at random and non-missing at random mechanisms scenarios. The methods are illustrated by modeling data from a stage III melanoma clinical trial. The results show that the methodology is rather robust and flexible, representing a competitive alternative to traditional techniques.  相似文献   
484.
In survival analysis, covariate measurements often contain missing observations; ignoring this feature can lead to invalid inference. We propose a class of weighted estimating equations for right‐censored data with missing covariates under semiparametric transformation models. Time‐specific and subject‐specific weights are accommodated in the formulation of the weighted estimating equations. We establish unified results for estimating missingness probabilities that cover both parametric and non‐parametric modelling schemes. To improve estimation efficiency, the weighted estimating equations are augmented by a new set of unbiased estimating equations. The resultant estimator has the so‐called ‘double robustness’ property and is optimal within a class of consistent estimators.  相似文献   
485.
In this paper we consider the impact of both missing data and measurement errors on a longitudinal analysis of participation in higher education in Australia. We develop a general method for handling both discrete and continuous measurement errors that also allows for the incorporation of missing values and random effects in both binary and continuous response multilevel models. Measurement errors are allowed to be mutually dependent and their distribution may depend on further covariates. We show that our methodology works via two simple simulation studies. We then consider the impact of our measurement error assumptions on the analysis of the real data set.  相似文献   
486.
The trimmed mean is a method of dealing with patient dropout in clinical trials that considers early discontinuation of treatment a bad outcome rather than leading to missing data. The present investigation is the first comprehensive assessment of the approach across a broad set of simulated clinical trial scenarios. In the trimmed mean approach, all patients who discontinue treatment prior to the primary endpoint are excluded from analysis by trimming an equal percentage of bad outcomes from each treatment arm. The untrimmed values are used to calculated means or mean changes. An explicit intent of trimming is to favor the group with lower dropout because having more completers is a beneficial effect of the drug, or conversely, higher dropout is a bad effect. In the simulation study, difference between treatments estimated from trimmed means was greater than the corresponding effects estimated from untrimmed means when dropout favored the experimental group, and vice versa. The trimmed mean estimates a unique estimand. Therefore, comparisons with other methods are difficult to interpret and the utility of the trimmed mean hinges on the reasonableness of its assumptions: dropout is an equally bad outcome in all patients, and adherence decisions in the trial are sufficiently similar to clinical practice in order to generalize the results. Trimming might be applicable to other inter‐current events such as switching to or adding rescue medicine. Given the well‐known biases in some methods that estimate effectiveness, such as baseline observation carried forward and non‐responder imputation, the trimmed mean may be a useful alternative when its assumptions are justifiable.  相似文献   
487.
This paper is concerned with the Bayesian estimation of nonlinear stochastic differential equations when observations are discretely sampled. The estimation framework relies on the introduction of latent auxiliary data to complete the missing diffusion between each pair of measurements. Tuned Markov chain Monte Carlo (MCMC) methods based on the Metropolis‐Hastings algorithm, in conjunction with the Euler‐Maruyama discretization scheme, are used to sample the posterior distribution of the latent data and the model parameters. Techniques for computing the likelihood function, the marginal likelihood, and diagnostic measures (all based on the MCMC output) are developed. Examples using simulated and real data are presented and discussed in detail.  相似文献   
488.
Missing data analysis requires assumptions about an outcome model or a response probability model to adjust for potential bias due to nonresponse. Doubly robust (DR) estimators are consistent if at least one of the models is correctly specified. Multiply robust (MR) estimators extend DR estimators by allowing for multiple models for both the outcome and/or response probability models and are consistent if at least one of the multiple models is correctly specified. We propose a robust quasi-randomization-based model approach to bring more protection against model misspecification than the existing DR and MR estimators, where any multiple semiparametric, nonparametric or machine learning models can be used for the outcome variable. The proposed estimator achieves unbiasedness by using a subsampling Rao–Blackwell method, given cell-homogenous response, regardless of any working models for the outcome. An unbiased variance estimation formula is proposed, which does not use any replicate jackknife or bootstrap methods. A simulation study shows that our proposed method outperforms the existing multiply robust estimators.  相似文献   
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