Modeling proportions and marginal counts simultaneously for clustered multinomial data with random cluster sizes

Clustered multinomial data with random cluster sizes commonly appear in health, environmental and ecological studies. Traditional approaches for analyzing clustered multinomial data contemplate two assumptions. One of these assumptions is that cluster sizes are fixed, whereas the other demands cluster sizes to be positive. Randomness of the cluster sizes may be the determinant of the within-cluster correlation and between-cluster variation. We propose a baseline-category mixed model for clustered multinomial data with random cluster sizes based on Poisson mixed models. Our orthodox best linear unbiased predictor approach to this model depends only on the moment structure of unobserved distribution-free random effects. Our approach also consolidates the marginal and conditional modeling interpretations. Unlike the traditional methods, our approach can accommodate both random and zero cluster sizes. Two real-life multinomial data examples, crime data and food contamination data, are used to manifest our proposed methodology.     

Bayesian longitudinal models for paediatric kidney transplant recipients

Chronic kidney disease is a progressive loss of renal function which results in the inability of the kidneys to properly filter waste from the blood. Renal function is usually estimated by the glomerular filtration rate (eGFR), which decreases with the worsening of the disease. Bayesian longitudinal models with covariates, random effects, serial correlation and measurement error are discussed to analyse the progression of eGFR in first transplanted children taken from a study in València, Spain.     

A Computational Bayesian Method for Generalized Semiparametric Regression Models

To better understand the power shift and the U.S. role compared to China and others regional actors, the Chicago Council on Global Affairs and the East Asia Institute (EAI) surveyed people in six countries - China, Japan, South Korea, Vietnam, Indonesian, and the United States - in the first half of 2008 about regional security and economic integration in Asia and about how these nations perceive each other (Bouton et al., 2010 Bouton, M., Steven, K., Benjamin, P., and Gregory, H. (2010). Soft power in Asia survey, 2008. ICPSR25342-v1. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2010-04-05. doi:10.3886/ICPSR25342.v1[Crossref] , [Google Scholar]). There exists latent variance that cannot be adequately explained by parametric models. This is, in large part, due to the hidden structures and latent stories that from in unexpected ways. Therefore, a new Gibbs sampler is developed here in order to reveal preciously unseen structures and latent variances found in the survey dataset of Bouton et al. This new sampler is based upon the semiparametric regression, a well-known tool frequently utilized in order to capture the functional dependence between variables with fixed effect parametric and nonlinear regression. This is then extended to a generalized semiparametric regression for binary responses with logit and probit link function. The new sampler is then developed for the generalized linear mixed model with a nonparametric random effect. It is expressed as nonparametric regression with the multinomial-Dirichlet distribution for the number and positions of knots.     

高职院校学生管理混合战略博弈分析

通过问卷调查的方式,了解并分析当前高职院校在校学生学习、生活及学生管理工作的现状,建立完全信息混合战略博弈模型,解析学校与学生在管理和被管理过程中的行为选择原因,并就高职院校的学生管理工作提出了几点建议。     

公司的本质——兼论国企混合所有制改革

公司是企业的一种特殊形态,公司不仅具备企业的一般本质,而且也具有自身的特殊本质.公司不同于自然人企业,它采取两权分离的形式,其股权能够标准化并借助资本市场得以高速地流动.两权分离使得公司的经营者专业化、专家化,从而大大提高公司的生产效率.股权在资本市场的高速流动使得资本市场配置资源的效率大大提高,从而提高整个社会的生产效率,其结果就提高了整个社会生产力.公司股权的多元化以及公司股权结构的相互制衡性使得公司的所有权特征被逐渐淡化,公司是一个所有的所有者进行投资的平台,它能够大大提高生产经营效率.正是在这个意义上讲,国有企业必须向公司制企业转换,由于这种向公司制企业的转换,从而形成了混合所有制的公司制企业.     

Approximate testing in two-stage nonlinear mixed models

We investigate here small sample properties of approximate F-tests about fixed effects parameters in nonlinear mixed models. For estimation of population fixed effects parameters as well as variance components, we apply the two-stage approach. This method is useful and popular when the number of observations per sampling unit is large enough. The approximate F-test is constructed based on large-sample approximation to the distribution of nonlinear least-squares estimates of subject-specific parameters. We recommend a modified test statistic that takes into consideration approximation to the large-sample Fisher information matrix (See [Volaufova J, Burton JH. Note on hypothesis testing in mixed models. Oral presentation at: LINSTAT 2012/21st IWMS; 2012; Bedlewo, Poland]). Our main focus is on comparing finite sample properties of broadly used approximate tests (Wald test and likelihood ratio test) and the modified F-test under the null hypothesis, especially accuracy of p-values (See [Volaufova J, LaMotte L. Comparison of approximate tests of fixed effects in linear repeated measures design models with covariates. Tatra Mountains. 2008;39:17–25]). For that purpose two extensive simulation studies are conducted based on pharmacokinetic models (See [Hartford A, Davidian M. Consequences of misspecifying assumptions in nonlinear mixed effects models. Comput Stat and Data Anal. 2000;34:139–164; Pinheiro J, Bates D. Approximations to the log-likelihood function in the non-linear mixed-effects model. J Comput Graph Stat. 1995;4(1):12–35]).     

Likelihood Inference for Spatial Generalized Linear Mixed Models

Spatial modeling is widely used in environmental sciences, biology, and epidemiology. Generalized linear mixed models are employed to account for spatial variations of point-referenced data called spatial generalized linear mixed models (SGLMMs). Frequentist analysis of these type of data is computationally difficult. On the other hand, the advent of the Markov chain Monte Carlo algorithm has made the Bayesian analysis of SGLMM computationally convenient. Recent introduction of the method of data cloning, which leads to maximum likelihood estimate, has made frequentist analysis of mixed models also equally computationally convenient. Recently, the data cloning was employed to estimate model parameters in SGLMMs, however, the prediction of spatial random effects and kriging are also very important. In this article, we propose a frequentist approach based on data cloning to predict (and provide prediction intervals) spatial random effects and kriging. We illustrate this approach using a real dataset and also by a simulation study.     

中间组织在技术标准形成中的作用研究

论述中间组织是技术标准相关者的联盟形式,各个技术标准相关者通过中间组织形成网络作用并参与技术标准的制定过程,中间组织是制定技术标准的有效形式.