王绩服食与诗歌创作

王绩是唐初的隐逸诗人,他否定道教神仙思想,而追求生命质量,一生坚持服食;他服食的是草木类药物,多数具有滋补性能,他的服食与神仙术了无关涉。隐逸生活（包括服食）培养了他的自然情操,提高了他感受自然和闲居生活的审美能力,从而形成了他自然、淳朴、雅淡的诗风。     

我国转型期黄毒赌现象中的非理性因素分析

非理性因素在黄毒赌中起着重要的作用.本文着重分析欲望、意志、无意识和信念等非理性因素与黄毒赌之间的内生关系,并从非理性层面探讨预防和扫除黄毒赌的对策.     

A qualitative case study of a Korean former addict’s existential self‐interpretation and identity transformation

This study explored the case of a former addict, focusing on his existential self‐interpretation and identity transformation process. This study began from the question of whether philosophical processes related to existential self‐interpretation could lead to the formation of the concept of bottoming out and of identity transformation. To answer this question, the study analyzed the case of a male in his mid‐forties who was addicted to drugs for approximately 30 years and has only recently maintained abstinence. The study used the phenomenological approach to determine the meaning drugs held for him in each stage, and what drug‐related identity he had in each stage. Further, this study identified the integrative implications of these meanings in terms of existential self‐interpretation and identity transformation. The four different identities the man identified for the four stages of his life were juvenile delinquent, gang member, half‐gangster, and breadwinner, and the associated meanings drugs had for him during each period were “glue,” “filthy,” “leeches,” and “abstinence,” respectively. Finally, this study elucidated the integration of these meanings through the hermeneutic circle, identified the social welfare implications of the findings, and developed educational recommendations.     

Exploring Shame,Guilt, and Risky Substance Use Among Sexual Minority Men and Women

This study examined the interrelations among shame-proneness, guilt-proneness, internalized heterosexism (IH), and problematic substance use among 389 gay, lesbian, and bisexual men and women. Problematic alcohol and drug use were positively related to shame-proneness and negatively related to guilt-proneness. Bisexuals reported riskier substance use behaviors, lower levels of guilt-proneness, and higher levels of IH than gay men and lesbians. Furthermore, study findings indicated that shame and IH are related. Additional investigations of these associations would supplement current understandings of sexual minority stress and advance the development of substance-related intervention and prevention efforts targeting sexual minorities.     

Adaptive phase I/II clinical trials for drug combination assessment in oncology using the outcomes of each cycle

Many new anticancer agents can be combined with existing drugs, as combining a number of drugs may be expected to have a better therapeutic effect than monotherapy owing to synergistic effects. Furthermore, to drive drug development and to reduce the associated cost, there has been a growing tendency to combine these as phase I/II trials. With respect to phase I/II oncology trials for the assessment of dose combinations, in the existing methodologies in which efficacy based on tumor response and safety based on toxicity are modeled as binary outcomes, it is not possible to enroll and treat the next cohort of patients unless the best overall response has been determined in the current cohort. Thus, the trial duration might be potentially extended to an unacceptable degree. In this study, we proposed a method that randomizes the next cohort of patients in the phase II part to the dose combination based on the estimated response rate using all the available observed data upon determination of the overall response in the current cohort. We compared the proposed method to the existing method using simulation studies. These demonstrated that the percentage of optimal dose combinations selected in the proposed method is not less than that in the existing method and that the trial duration in the proposed method is shortened compared to that in the existing method. The proposed method meets both ethical and financial requirements, and we believe it has the potential to contribute to expedite drug development.     

Building,Engaging, and Sustaining a Continuum of Care From Harm Reduction to Recovery Support: The Rutgers Alcohol and Other Drug Assistance Program

Since 1983, the focus of the Rutgers Alcohol and Other Drug Assistance Program (ADAP) has been developing policies, training staff to identify students at risk, developing and implementing evidence-based screening and brief interventions, providing short-term counseling by professionals trained in alcohol and other drug abuse to assist students beyond brief interventions, identifying effective treatment for college students, developing a campus recovery program, on-campus recovery housing, and other supports for students in recovery. This article presents a case study of the Rutgers ADAP program, of building and sustaining a program committed to engaging students in both evidence-based risk reduction interventions and an on-campus recovery community given their stage of change and motivation to make changes. Historical milestones are described as part of a creative model for intervention. We identify the challenges of integrating substance abuse recovery into campus mental health programs, and of integrating recovery into other university communities.     

国外新型隐身材料的研究现状和发展方向

分析了隐身材料在隐身技术中的重要地位 ,较详细地介绍了手性材料、纳米材料、导电高聚物材料、多晶铁纤维材料的研究和应用现状 .最后指出 ,多频谱隐身材料和智能型隐身材料是隐身材料中的两个最主要发展方向     

HPLC测定氨酚伪麻美芬片Ⅱ/氨麻苯美片中对乙酰氨基酚血药浓度

目的建立高效液相色谱法测定氨酚伪麻美芬片Ⅱ/氨麻苯美片中对乙酰氨基酚的血药浓度。方法血浆样品用6%高氯酸沉淀蛋白。色谱柱为Zorbax Eclipse XDB-C18柱（150 mm×4.6 mm, 5 μm）,流动相为0.02 mol·L-1甲酸铵溶液（含甲酸0.2%）-甲醇-乙腈（91∶4.5∶4.5）,流速为1.0 mL·min-1,紫外检测波长245 nm。结果血浆中内源性物质对样品测定无干扰。本方法线性范围为0.1～20 μg·mL-1 (r=0.999 6),最低定量浓度为0.1 μg·mL-1,方法回收率为99.8%～101.5%,日内、日间RSD均小于12%。结论本法简便、准确,适用于对乙酰氨基酚药代动力学的研究。