Censored median regression and profile empirical likelihood

We implement profile empirical likelihood-based inference for censored median regression models. Inference for any specified subvector is carried out by profiling out the nuisance parameters from the “plug-in” empirical likelihood ratio function proposed by Qin and Tsao. To obtain the critical value of the profile empirical likelihood ratio statistic, we first investigate its asymptotic distribution. The limiting distribution is a sum of weighted chi square distributions. Unlike for the full empirical likelihood, however, the derived asymptotic distribution has intractable covariance structure. Therefore, we employ the bootstrap to obtain the critical value, and compare the resulting confidence intervals with the ones obtained through Basawa and Koul’s minimum dispersion statistic. Furthermore, we obtain confidence intervals for the age and treatment effects in a lung cancer data set.     

EXACT P‐VALUES FOR DISCRETE MODELS OBTAINED BY ESTIMATION AND MAXIMIZATION

In constructing exact tests from discrete data, one must deal with the possible dependence of the P‐value on nuisance parameter(s) ψ as well as the discreteness of the sample space. A classical but heavy‐handed approach is to maximize over ψ. We prove what has previously been understood informally, namely that maximization produces the unique and smallest possible P‐value subject to the ordering induced by the underlying test statistic and test validity. On the other hand, allowing for the worst case will be more attractive when the P‐value is less dependent on ψ. We investigate the extent to which estimating ψ under the null reduces this dependence. An approach somewhere between full maximization and estimation is partial maximization, with appropriate penalty, as introduced by Berger & Boos (1994, P values maximized over a confidence set for the nuisance parameter. J. Amer. Statist. Assoc. 89 , 1012–1016). It is argued that estimation followed by maximization is an attractive, but computationally more demanding, alternative to partial maximization. We illustrate the ideas on a range of low‐dimensional but important examples for which the alternative methods can be investigated completely numerically.     

Do difference scores make a difference on the third-person effect?

Researchers from different fields have been intrigued but also confused with regard to the ways of conceptualizing and operationalizing difference. This article critically reviewed a number of existing means of operationalizing difference and mathematically explicated and empirically tested why difference scores were problematic and why the diamond model that aimed to replace difference scores was equally troublesome. Ultimately, this article recommended polynomial regression as an alternative to difference scores.     

A note on the moments of stochastic shrinkage parameters in ridge regression

The purpose of this note is to gain insight on the performance of two well known operational Ridge Regression estimators by deriving the moments of their stochastic shrinkage parameters. We also show that, under certain conditions, one of them has bounded moments.     

Optimum Experimental Designs for Choosing Between Competitive and Non Competitive Models of Enzyme Inhibition

In the study of the inhibition of enzyme reactions the Michaelis–Menten model is extended to include two experimental variables and three or more parameters. We combine the three-parameter models for competitive and non competitive inhibition in a four-parameter model and use optimum design theory to find D- and Ds-optimum designs for discriminating between the models. These designs are compared with compound T-optimum designs which provide the most powerful tests for discrimination between models. A single design is found with high discrimination efficiency whichever model is true.     

On confidence limits for the difference of two binomial parameters

In the present article we suggest two new methods for calculating approximate confidence limits for the differences of the two binomial parameters. Different methods for determining the confidence interval are compared.     

A pilot Monte Carlo study of two sequential estimation procedures based on generalized U-statistics

Recently two sequential estimation procedures based on generalized U-statistics have appeared in the statistical literature [Williams and Sen (1973, 1974)]. One of these procedures concerns the multi-sample problem of estimating a vector of parameters when the total sample size is fixed. The other procedure concerns the multi-sample problem of constructing a confidence ellipsoid of bounded maximum width for a vector of parameters. To supplement the asymptotic theory discussed in these earlier papers, a Monte Carlo study investigating the efficiency of these procedures for moderate sample sizes would be useful. This paper describes a preliminary Monte Carlo study utilizing a small number of replications and performed to provide information for the design of a more extensive study.     

Some recent results for series system reliability

Asymptotic properties of key test results ate obtained. Some further results on the Lindstrom-Madden method are given, including a binomial-Poisson inequality, together with some numerical examples. Simplified proofs of some results of Pledger and Proschan (1971) and Nevius, Proschan and Sethuraman (1977) are provided and the listing of a FORTRAN program to calculate a lower bound to the 1-α lower confidence limit on the system reliability is given.