A comparison of tests of homogeneity for sparse contingency tables

Five tests of homogeneity for a 2x(k+l) contingency table are compared using Monte Carlo techniques. For these studiesit is assumed that k becomes large in such a way that thecontingency table is sparse for 2xk of the cells, but the sample size in two of the cells remains large. The test statistics studied are: the chi-square approximation to the Pearson test statistic, the chi-square approximation to the likelihood ratio statistic, the normal approximation to Zelterman's (1984)the normal approximation to Pearson's chi-square, and the normal approximation to the likelihood ratio statistic. For the range of parameters studied the chi-square approximation to Pearson's statistic performs consistently well with regard to its size and power.     

A model for comparisons with ordered categorical data

A model developed by Andrich for ordered categorical data is extended to develop tests for treatment effects with paired or matched samples. In particular, this includes analysis for pre-post studies and crossover designs. Some advantages of this model are that it allows for misclassification of subjects, yields reasonable conditional requirements for exact analysis, a normal approximation is good for all but the smallest of sample sizes, and it is relatively simple mathematically. Furthermore, the form of the tests derived are logical extensions of tests for unordered categories.     

Linear Models Methods for Some Rank Function Analyses of Ordinal Categorical Data

This paper is concerned with the analysis of ordinal data through linear models for rank function measures.Primary attention is directed at pairwise Mann-Whitney statistics for which dimension reduction is managed by use of a Bradley-Terry log-linear structure.The nature of linear models for such quantities is contrasted with that for mean ranks (or ridits).Aspects of application are illustrated with an example for which results of other methods are also given.     

Providing Consulting Experiences Through Role Playing in a Graduate Statistics Course

An effective method for improving the communication skills of graduate students in statistics and biostatistics is to provide consultations with non‐statistical researchers. Unfortunately, those experiences can be difficult to arrange or occur too infrequently to be reliable. The current study sought to help students develop both written and oral communication skills within an existing graduate biostatistics course by having students partake in role‐playing consultations. Though the class size was small, the students felt these activities helped improve their oral and written communication skills, and made them more aware of a biostatistician's role in consulting. There was also modest improvement in the students perceived function as a consulting biostatistician. Simulated consultations can be an effective educational tool for promoting the development of soft skills necessary for developing successful statisticians, can be implemented in existing courses, and do not require reliance upon external collaborators. Embedding these types of exercises within an existing curriculum can also be a cost‐effective alternative for programs that do not have formal consulting training.     

EXACT INFERENCE FOR FAMILY DISEASE CLUSTERS

In many epidemiologic studies the first indication of an environmental or genetic contribution to the risk of disease is the way in which the diseased cases cluster within the same family units. The concept of clustering is contrasted with incidence. We assume that all individuals within the same family are independent, up to their disease status. This assumption is used to provide an exact test of the initial hypothesis of no familial link with the disease, conditional on the number of diseased cases and the sizes of the various family units. Ascertainment bias is described and the appropriate sampling distribution is demonstrated. Two numerical examples with published data illustrate these methods.     

Bayesian estimation of log odds ratios over two-way contingency tables with intraclass correlated cells

In this article, a Bayesian approach is proposed for the estimation of log odds ratios and intraclass correlations over a two-way contingency table, including intraclass correlated cells. Required likelihood functions of log odds ratios are obtained, and determination of prior structures is discussed. Hypothesis testing for log odds ratios and intraclass correlations by using the posterior simulations is outlined. Because the proposed approach includes no asymptotic theory, it is useful for the estimation and hypothesis testing of log odds ratios in the presence of certain intraclass correlation patterns. A family health status and limitations data set is analyzed by using the proposed approach in order to figure out the impact of intraclass correlations on the estimates and hypothesis tests of log odds ratios. Although intraclass correlations are small in the data set, we obtain that even small intraclass correlations can significantly affect the estimates and test results, and our approach is useful for the estimation and testing of log odds ratios in the presence of intraclass correlations.     

Two-step jackknife bias reduction for logistic regression mles

Maximum likelihood estimates (MLEs) for logistic regression coefficients are known to be biased in finite samples and consequently may produce misleading inferences. Bias adjusted estimates can be calculated using the first-order asymptotic bias derived from a Taylor series expansion of the log likelihood. Jackknifing can also be used to obtain bias corrected estimates, but the approach is computationally intensive, requiring an additional series of iterations (steps) for each observation in the dataset.Although the one-step jackknife has been shown to be useful in logistic regression diagnostics and i the estimation of classification error rates, it does not effectively reduce bias. The two-step jackknife, however, can reduce computation in moderate-sized samples, provide estimates of dispersion and classification error, and appears to be effective in bias reduction. Another alternative, a two-step closed-form approximation, is found to be similar to the Taylo series method in certain circumstances. Monte Carlo simulations indicate that all the procedures, but particularly the multi-step jackknife, may tend to over-correct in very small samples. Comparison of the various bias correction proceduresin an example from the medical literature illustrates that bias correction can have a considerable impact on inference     

Analysis of categorical data obtained by stratified random sampling

Analysis of categorical data by linear models is extended to data obtained by stratified random sampling. It is shown that, asymptotically, proportional allocation reduces the variances of estimators from those obtained hy simple random sampling. The difference between the asymptotic covariance matrices of estimated parameters obtained by simple random sampling and stratified random sampling with proportional allocation is shown to be positive definite vinder fairly non-restrictive conditions, when an asymptotically efficient method of estimation is used. Data from a major community study of mental health are used to illustrate application of the technique.     

A note on the asymptotic variance of the gray and williams measure of partial association

The correct asymptotic variancef or the partial association analog of Goodman and Kruskal's T measure of associati o n based on proportional prediction is derived for both full multinomial sampling and product multinomial sampling. These results are illustrated within the context of an example data set.     

Power-Divergence Test Statistics for Testing Linear by Linear Association

Power-divergence test statistics have been considered to test linear by linear association for two-way contingency tables. These test statistics have been compared based on designed simulation study and asymptotic results for 2 × 2, 2 × 3, and 3 × 3 tables. According to the results, there are test statistics with better properties than the well-known likelihood ratio test statistic for small and moderate samples.