The time‐dependent “cure‐death” model investigating two equally important endpoints simultaneously in trials treating high‐risk patients with resistant pathogens

A variety of primary endpoints are used in clinical trials treating patients with severe infectious diseases, and existing guidelines do not provide a consistent recommendation. We propose to study simultaneously two primary endpoints, cure and death, in a comprehensive multistate cure‐death model as starting point for a treatment comparison. This technique enables us to study the temporal dynamic of the patient‐relevant probability to be cured and alive. We describe and compare traditional and innovative methods suitable for a treatment comparison based on this model. Traditional analyses using risk differences focus on one prespecified timepoint only. A restricted logrank‐based test of treatment effect is sensitive to ordered categories of responses and integrates information on duration of response. The pseudo‐value regression provides a direct regression model for examination of treatment effect via difference in transition probabilities. Applied to a topical real data example and simulation scenarios, we demonstrate advantages and limitations and provide an insight into how these methods can handle different kinds of treatment imbalances. The cure‐death model provides a suitable framework to gain a better understanding of how a new treatment influences the time‐dynamic cure and death process. This might help the future planning of randomised clinical trials, sample size calculations, and data analyses.     

Housing of Seniors in the Czech Republic: Challenges for Social Services

The article focuses on the housing market, the behavior and motivations of senior households to move or to stay in place. Knowing if and why seniors decide to move at retirement is a critical factor for the establishment of social service policies in terms of their structure, location, and provision.

This study uses secondary data based on information about Czech households collected by the Czech Statistical Office (CSO). The data are annually collected via sample surveys of the income and living conditions of households (EU-SILC). The sample covers more than eight thousands of households. Analyzed data cover the period 2007–2012 when the abolishment of rent regulation in the Czech Republic took place. It is hypothesized that an impact like this might increase the willingness to move and reveal the factors which underlie the decisions of particular households.

The results indicated that most Czech households that decided to move during the study period were driven by the increased financial burden of housing. Other factors, including the availability of social services and public utilities within the current location, played only minor roles. It seems that Czech senior households act in a very pragmatic and rational manner when deciding whether to stay in place or move, with the majority of households preferring not to move. Social policies should, therefore, concentrate on providing services for the current locations rather than on the construction of new social housing.     

Racial/Ethnic Patterns of Kindergarten School Enrollment in the United States

Enrollment into unequal schools at the start of formal education is an important mechanism for the reproduction of racial/ethnic educational inequalities. We examine whether there are racial/ethnic differences in school enrollment options at kindergarten, the start of schooling. We use nationally representative data from the Early Childhood Longitudinal Study‐Birth Cohort (ECLS‐B) to model whether parents seek information about their child's school before enrolling, whether parents move to a location so that a child can attend a certain school, or whether parents enroll their child in a school other than the assigned public school. Results indicate that enrollment patterns differ greatly across race/ethnicity. Whereas Black families are the most likely to seek information on a school's performance, White families are the most likely to use the elite option of choosing their residential location to access a particular school. These differences persist when controlling for socioeconomic status and sociogeographic location. Kindergarten enrollment patterns preserve the advantages of White families, perpetuating racial/ethnic disparities through multiple institutions and contributing to intergenerational processes of social stratification. Research should continue to examine specific educational consequences of housing inequities and residential segregation.     

College-conocimiento: toward an interdisciplinary college choice framework for Latinx students

This paper builds upon Perna’s college choice model by integrating Anzaldúa’s theory of conocimiento to propose an interdisciplinary college choice framework for Latinx students. Using previous literature, this paper proposes college-conocimiento as a framework that contextualizes Latinx student college choices within the inequitable distribution of institutional resources in the K-12 system. In particular, the framework centers on the notion that a lack of adequate college guidance can influence a cyclical Latinx college choice process. College-conocimiento is defined as a serpentine process where Latinx students reflect on the college information that they receive, in relation to their intersectional identities when preparing for college. The pathway of college-conocimiento entails seven cyclical spaces and aims for students to develop a reflective college consciousness, exemplified through self-advocacy and supporting peers with the college choice process. This paper challenges college choice as a sequential process by noting that students can repeat stages as needed.     

基于ART及多风险规避的交通网络均衡模型

随着对交通系统不确定性认识的深入,以绝对理性为基础的“期望效用理论”在风险环境下的路径选择分析中显示出局限性,而“预期后悔理论”则为之提供了新的分析思路.将预期后悔理论应用到风险环境下的路径选择分析中,将出行者一致风险规避的假设扩展到多风险规避,建立了基于后悔理论及多风险规避出行特征的交通网络随机用户均衡变分不等式模型,并给出了求解算法.通过算例分析发现,后悔心理对出行者的路径选择并不总是显著的.在非风险环境及极端风险环境中,后悔心理对出行者的路径选择影响是微弱的,但是当环境处于极端风险与非风险之间时,后悔心理对出行者路径选择有着较为显著的影响.     

The effects of information form and domain-specific knowledge on choice deferral

Three studies examined the effect of information form on choice deferral in consumer choice and explored the moderating role of knowledge about the product domain. Two theoretical approaches were contrasted: (1) The process approach predicting that choice deferral varies as a function of information form, and (2) the communication approach predicting an interaction of information form and domain-specific knowledge. Participants were presented with different laptops described in an absolute (e.g. ‘300 GB hard disc’), evaluative-numerical (e.g. ‘hard disc with 30 out of 100 points in an expert rating’) or evaluative-verbal (e.g. ‘bad hard disc’) information form, and they could choose to buy one of the laptops or defer. Domain-specific knowledge was also assessed. In Study 1, evaluative-numerical and evaluative-verbal values led to more deferral in people with high domain-specific knowledge. The pattern for evaluative-numerical and evaluative-verbal values was replicated for a different information organization in Study 2. Study 3 showed that absolute values led to more deferral the less knowledgeable participants were and demonstrated that domain-specific knowledge and deferral were unrelated when absolute and evaluative-verbal values were presented in combination. In sum, the results support the communication approach and have methodological implications for decision research and theoretical implications for understanding choice deferral in real-life decisions.     

Influential factors in the choice of public transportation or cars as the mode of transportation in habitual commutes / Factores que influyen en la elección del transporte público o el automóvil como modo de transporte en los desplazamientos habituales

The goal of this study is to analyse the differences in attitudes towards habitual modes of transportation among users of public and private transportation. The explanatory capacity of attitudes when determining the mode choice, along with the structural and sociodemographic factors, are also verified. The study was performed in three Spanish cities with 742 participants. The results revealed that cars are better rated than public modes of transportation in the attributes associated with immediate advantages (i.e., speed and availability) and convenience. Subways are highly rated in both immediate and deferred advantages (environment, safety, cost and health). Buses are the mode rated the lowest of the three. Using logistic regression, it was verified that the variance explained by a model that includes attitudes (R² = .639) is higher than the variance explained by a model based solely on variables related to infrastructures (R² = .489). The discussion of these results includes proposals aimed at decreasing car use.     

社会工作专业教学组织机制：问题与选择

优化教学组织机制是提高社会工作专业教育质量不可或缺的重要一环。面对社会工作专业课堂教学和实践教学他组织与自组织相分离的现实困境,教师要科学选择介入策略,勇于革新教学方法,以实现教学组织机制的优化。     

Effects of Social Supports on the Career Choice Consideration of Chinese Farmers: A Social Cognitive Perspective

Drawing from social cognitive career theory ( Lent, Brown, & Hackett, 1994 ), this study explored social supports’ influence on the career choice consideration of farmers during China's current process of urbanization. A questionnaire was designed based on interviews with 140 people and a pretest with a sample of 419 participants. A total of 628 participants were involved in the formal questionnaire survey. Results indicated that social supports had a dual effect: Positive supports were indirectly related to career choice consideration through the mediation of career self‐efficacy, whereas negative supports were related to career choice consideration directly. Implications for future research and the development of a career guidance and social support system for Chinese farmers are discussed.