Estimation of multiple gamma scale-parameters: bayes estimation subject to uniform domination

Simultaneous estimation of p gamma scale-parameters is considered under squared-error loss. The problem of minimizing, subject to uniform risk domination, the Bayes risk (or more generally the posterior expected loss) against certain conjugate or mixtures of conjugate priors is considered. Rather surprisingly, it is shown that the minimization can be done conditionally, thus avoiding variational arguments. Relative savings loss (and a posterior version thereof) are found, and it is found that in the most favorable situations, Bayesian robustness can be achieved without sacrificing substantial subjective Bayesian gains.     

A simple test for new better than used in expectation

We present a statistical procedure to test that a life distribution is exponential against the al ternative that it is continuous new better than used in expectation. The test is shown to be consistent and asymptotic relative efficiency resul ts are obtained against the competitor developed earlier by Hollander and Proschan [2], for certain families of alternatives.     

On the behaviour of some transforms of the sample correlation coefficient in samples from the bivariate t and the bivariate X2distribution

The present paper studies the normality of five transformations suggested in the literature to normalize the sample correlation coefficient. The parent populations are the bivariate t and the bivariate X ²The results in the previous work of Subrahmaniam and Gajjar are exploited to assess their performance. The density estimation procedure of Tarter and Kronmal is used to provide empiric support to the asymptotic results     

论商号的转让

商号是商主体用来表示其营业的名称,商号具有人格属性和财产属性。商号的法律属性对商号的转让具有重要意义。随着经济生活的发展,商号的财产性日趋明显,这有利于商号的转让;同时,商号的人格属性与财产性相对独立,也为商号的转让奠定了基础。商号转让的基础、模式、程序、效力在我国现行法律中缺乏相关规定,值得研究探讨。     

Evaluation of different statistical methods using SAS software: an in silico approach for analysis of real-time PCR data

Real-time polymerase chain reaction (PCR) is reliable quantitative technique in gene expression studies. The statistical analysis of real-time PCR data is quite crucial for results analysis and explanation. The statistical procedures of analyzing real-time PCR data try to determine the slope of regression line and calculate the reaction efficiency. Applications of mathematical functions have been used to calculate the target gene relative to the reference gene(s). Moreover, these statistical techniques compare C_t (threshold cycle) numbers between control and treatments group. There are many different procedures in SAS for real-time PCR data evaluation. In this study, the efficiency of calibrated model and delta delta C_t model have been statistically tested and explained. Several methods were tested to compare control with treatment means of C_t. The methods tested included t-test (parametric test), Wilcoxon test (non-parametric test) and multiple regression. Results showed that applied methods led to similar results and no significant difference was observed between results of gene expression measurement by the relative method.     

Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints

Adaptive designs for multi-armed clinical trials have become increasingly popular recently because of their potential to shorten development times and to increase patient response. However, developing response-adaptive designs that offer patient-benefit while ensuring the resulting trial provides a statistically rigorous and unbiased comparison of the different treatments included is highly challenging. In this paper, the theory of Multi-Armed Bandit Problems is used to define near optimal adaptive designs in the context of a clinical trial with a normally distributed endpoint with known variance. We report the operating characteristics (type I error, power, bias) and patient-benefit of these approaches and alternative designs using simulation studies based on an ongoing trial. These results are then compared to those recently published in the context of Bernoulli endpoints. Many limitations and advantages are similar in both cases but there are also important differences, specially with respect to type I error control. This paper proposes a simulation-based testing procedure to correct for the observed type I error inflation that bandit-based and adaptive rules can induce.     

On some classifiers based on multivariate ranks

Non parametric approaches to classification have gained significant attention in the last two decades. In this paper, we propose a classification methodology based on the multivariate rank functions and show that it is a Bayes rule for spherically symmetric distributions with a location shift. We show that a rank-based classifier is equivalent to optimal Bayes rule under suitable conditions. We also present an affine invariant version of the classifier. To accommodate different covariance structures, we construct a classifier based on the central rank region. Asymptotic properties of these classification methods are studied. We illustrate the performance of our proposed methods in comparison to some other depth-based classifiers using simulated and real data sets.