基因编辑的刑法规制 ——兼论非法植入基因编辑、克隆胚胎罪中的“情节严重”

CRISPR-Cas9基因编辑技术的主要特点在于操作简便、准确性高以及可遗传等,该技术在造福人类的同时也催生了基因编辑的风险。按照基因编辑的目的,可将基因编辑分为治疗型、预防型和增效型三种。增效型基因编辑以及将人类胚胎植入动物体内或将动物胚胎植入人体内的行为,严重违背医学伦理且造成人类毁灭危险,应属于刑法非法植入基因编辑、克隆胚胎罪中的情节严重。其他基因编辑行为也应视情况构成毁坏财物罪、侵犯公民个人信息罪、盗窃罪等。此外,为实现罪责刑相适应,需在相关行政法规中制定明确的技术标准,出现重伤或死亡结果时,根据行为人主观罪过视情况认定为非法植入基因编辑、克隆胚胎罪,故意伤害致人死亡或故意杀人罪。     

问责-避责关系新解：基于“行动-制度-环境”框架

问责与避责间的关系是责任政治研究的重要议题,其中,问责导致避责的机制亟待探究。以X县早稻生产政策过程为例,基于“行动-制度-环境”的分析框架,探讨上级问责与基层避责之间的关系机制。研究发现：基层干部避责行为是上级问责制度与基层社会环境共同作用的结果,是作为责任者的基层干部面对上级问责压力和农民抗拒压力的理性选择。为贯彻落实非粮化整治政策,上级通过责任分配、责任考核和督查问责制度,给基层干部施加了巨大的早稻生产责任压力。而农民在长期的生产历史过程中已经形成了以中稻种植模式为主导的、较为稳定的生产秩序,拒不执行早稻生产政策。承受双重压力的基层干部只能采取责任兜底的属地化机制、利益交换的市场化机制和联合避责的科层化机制来规避上级问责风险。作为行动者的基层干部运用自由裁量权,通过隐匿信息、集体负债等方式,在一定程度上改变了既有的制度-环境,再造了基层治理结构。     

欧美合成生物学应用的风险治理经验及启示

合成生物学技术的应用与发展为基础生命科学研究、人类健康、环境保护和经济增长做出了重要贡献。随着合成生物学变得更便宜、更容易使用和更容易获得,亟需建立行之有效的风险治理体系以防控其潜在的伦理道德、生物安全和生物安保风险,促进技术健康发展。通过观照欧美国家风险治理模式,建议预防风险与促进创新并重、伦理治理与法律规制“双管齐下”,以期为我国合成生物学监管提供有益经验、减少风险和控制利益冲突,促进我国合成生物学创新,规范合成生物学研究和生产。     

The Seveso Directive: An Italian Pilot Study in Enabling Communication

In 1982 the Council of the European Communities issued a Directive on the Major Accident Hazards of Certain Industrial Activities, commonly known as the Seveso Directive. Besides other requirements, the Directive specifies that members of the public liable to be affected by a major accident from certain industrial activities must be informed of safety measures and how they should behave in the event of an accident. The Directive was subsequently amended in an extensive way. Upon the transposition of the Seveso Directive and its amendments into national legislations, the 12 European Member States are faced with the task of "appropriately and effectively" informing the public about major accident hazards. Delays are observed throughout the community, both in transposing the Directives and implementing public information. A pilot study on "Risk Information Needs" was commissioned and carried out at two Seveso sites in Italy in order to begin to resolve some of the problems involved in the provision of public information and to suggest appropriate guidelines. One hundred subjects answered an experimental protocol designed to assess their "information needs." This article presents the theoretical background, the pragmatic aims, and the design of the study. It also summarizes its most relevant findings and suggests some recommendations for the provision of information to the public.     

改革目标和企业风险度测定─—现代企业制度建设的关键

在建立现代企业制度的探索中,原有的“承包制”在实践中已暴露它的不足,与改革的深入不相适应。企业的生机在于竞争和风险。在商品经济条件下,企业经营实际上就是经营者运用创新手段,将受损风险转化为超额收获。而企业生产经营所存在的诸多不确定因素,可以通过概率论中的中心极限定理和经验,借鉴计划评审法（ＰＥＲＴ）中概率估算法对企业的经验风险度作出有价值的测定。     

Coherent decision analysis with inseparable probabilities and utilities

This article explores the extent to which a decision maker's probabilities can be measured separately from his/her utilities by observing his/her acceptance of small monetary gambles. Only a partial separation is achieved: the acceptable gambles are partitioned into a set of belief gambles, which reveals probabilities distorted by marginal utilities for money, and a set of preference gambles, which reveals utilities reciprocally distorted by marginal utilities for money. However, the information in these gambles still enables us to solve the decision maker's problem: his/her utility-maximizing decision is the one that avoids arbitrage (i.e., incoherence or Dutch books).     

De minimis and equity in risk

Indices and orderings are developed for evaluating alternative strategies in the management of risk. They reflect the goals of reducing individual and collective risks, of increasing equity, and of assigning priority to the reduction and to the equity of high risks. Individual risk is defined as the (random or non-random) level of exposure to a danger. In particular the role of a lower negligibility level is investigated. A class of indices is proposed which involves two parameters, a negligibility level and a parameter of inequality aversion, and several interpretations of the indices are discussed. We provide a set of eight axioms which are necessary and sufficient for this class of indices, and we present an approach to deal with partial information on the parameters.     

獭兔养殖综合技术研究

对獭兔的适应性、饲养管理、疾病防治、产品加工等养殖综合技术进行了研究,提出了獭兔的“三改、两杯、两早一分和两选两适”规范化饲养管理制度和疾病综合防治技术措施,探索出了优质獭兔毛皮和“富钙兔肉脯”的加工工艺以及獭兔良种推广的有效途径。     

Tolerable or Acceptable: A Comparison of Risk Regulation in the United Kingdom and in the Netherlands

In managing major accident hazards in industry risk, both the United Kingdom and the Netherlands use quantitative risk analysis and quantified risk criteria. These should be understood in the historical, legal, and political context in which they were drawn up. Even when criteria are numerically the same they do not necessarily mean the same thing. The legal and historical context differs widely between the two countries. Nevertheless, it is surprising that the final results in terms of land use and levels of risk are very similar.     

Quantitative Estimates of Risk for Noncancer Endpoints

While quantitative estimates of risk have been a standard practice in cancer risk assessment for many years, no similar practice is evident in noncancer risk assessment. We use two recent examples involving methylmercury and arsenic to illustrate the negative impact of this discrepancy on risk communication and cost-benefit analysis. We argue for a more balanced treatment of cancer and noncancer risks and suggest an approach for reaching this goal.