General results for the Kumaraswamy-G distribution

For any continuous baseline G distribution [G.M. Cordeiro and M. de Castro, A new family of generalized distributions, J. Statist. Comput. Simul. 81 (2011), pp. 883–898], proposed a new generalized distribution (denoted here with the prefix ‘Kw-G’ (Kumaraswamy-G)) with two extra positive parameters. They studied some of its mathematical properties and presented special sub-models. We derive a simple representation for the Kw-G density function as a linear combination of exponentiated-G distributions. Some new distributions are proposed as sub-models of this family, for example, the Kw-Chen [Z.A. Chen, A new two-parameter lifetime distribution with bathtub shape or increasing failure rate function, Statist. Probab. Lett. 49 (2000), pp. 155–161], Kw-XTG [M. Xie, Y. Tang, and T.N. Goh, A modified Weibull extension with bathtub failure rate function, Reliab. Eng. System Safety 76 (2002), pp. 279–285] and Kw-Flexible Weibull [M. Bebbington, C.D. Lai, and R. Zitikis, A flexible Weibull extension, Reliab. Eng. System Safety 92 (2007), pp. 719–726]. New properties of the Kw-G distribution are derived which include asymptotes, shapes, moments, moment generating function, mean deviations, Bonferroni and Lorenz curves, reliability, Rényi entropy and Shannon entropy. New properties of the order statistics are investigated. We discuss the estimation of the parameters by maximum likelihood. We provide two applications to real data sets and discuss a bivariate extension of the Kw-G distribution.     

Using In Vitro High‐Throughput Screening Data for Predicting Benzo[k]Fluoranthene Human Health Hazards

Today there are more than 80,000 chemicals in commerce and the environment. The potential human health risks are unknown for the vast majority of these chemicals as they lack human health risk assessments, toxicity reference values, and risk screening values. We aim to use computational toxicology and quantitative high‐throughput screening (qHTS) technologies to fill these data gaps, and begin to prioritize these chemicals for additional assessment. In this pilot, we demonstrate how we were able to identify that benzo[k]fluoranthene may induce DNA damage and steatosis using qHTS data and two separate adverse outcome pathways (AOPs). We also demonstrate how bootstrap natural spline‐based meta‐regression can be used to integrate data across multiple assay replicates to generate a concentration–response curve. We used this analysis to calculate an in vitro point of departure of 0.751 μM and risk‐specific in vitro concentrations of 0.29 μM and 0.28 μM for 1:1,000 and 1:10,000 risk, respectively, for DNA damage. Based on the available evidence, and considering that only a single HSD17B4 assay is available, we have low overall confidence in the steatosis hazard identification. This case study suggests that coupling qHTS assays with AOPs and ontologies will facilitate hazard identification. Combining this with quantitative evidence integration methods, such as bootstrap meta‐regression, may allow risk assessors to identify points of departure and risk‐specific internal/in vitro concentrations. These results are sufficient to prioritize the chemicals; however, in the longer term we will need to estimate external doses for risk screening purposes, such as through margin of exposure methods.     

Introduction to the Special Section Value Development from Middle Childhood to Early Adulthood—New Insights from Longitudinal and Genetically Informed Research

Research into values at an early age has only started recently, although it has expanded quickly and dynamically in the past years. The purpose of this article is twofold: First, it provides an introduction to a special section that aims to help fill the gap in value development research. The special section brings together four new longitudinal and genetically informed studies of value development from the beginning of middle childhood through early adulthood. Second, this article reviews recent research from this special section and beyond, aiming to provide new directions to the field. With new methods for assessing children's values and an increased awareness of the role of values in children's and adolescents' development, the field now seems ripe for an in‐depth investigation. Our review of empirical evidence shows that, as is the case with adults, children's values are organized based on compatibilities and conflicts in their underlying motivations. Values show some consistency across situations, as well as stability across time. This longitudinal stability tends to increase with age, although mean changes are also observed. These patterns of change seem to be compatible with Schwartz's (1992) theory of values (e.g., if the importance of openness to change values increases, the importance of conservation values decreases). The contributions of culture, family, peers, significant life events, and individual characteristics to values are discussed, as well as the development of values as guides for behavior.     

内蒙古非物质文化遗产的精神内蕴论析

内蒙古历史源远流长、各民族聚集共处、民族文化多元一体,铸就了非物质文化遗产突出的历史和人文价值,也充实了其丰富的精神内涵。具体而言,包括开放包容的文化品质、顽强拼搏的进取意识、万物共生的价值观念、团结统一的理想追求。     

Mixtures of regression models with incomplete and noisy data

The estimation of the mixtures of regression models is usually based on the normal assumption of components and maximum likelihood estimation of the normal components is sensitive to noise, outliers, or high-leverage points. Missing values are inevitable in many situations and parameter estimates could be biased if the missing values are not handled properly. In this article, we propose the mixtures of regression models for contaminated incomplete heterogeneous data. The proposed models provide robust estimates of regression coefficients varying across latent subgroups even under the presence of missing values. The methodology is illustrated through simulation studies and a real data analysis.     

试论社会主义核心价值构建的人性维度

市场经济负面影响的日益显现及西方所谓普世价值的冲击，使不少国人陷入价值错乱、虚无的状态，亟待对其加强价值引导。社会主义核心价值的提出及构建可谓正当其时。价值与核心价值的构建，必须遵循人性维度。运用理性思维去把握人性，形成科学的人性理论，并将其付之于现实生活予以检验，把握人性的真实，才能为核心价值构建奠定人性的坚实基石。     

论中日茶道文化的意境与精神气质

中日茶道文化是东方文化中的两朵奇葩,但是由于诸多原因,中日茶道文化在意境和精神气质上有着较大区别:中国的茶道仪式自然随和,圆润融通,日本的茶道仪式则过于拘于程序和礼节;中国将饮茶发展为日常生活艺术,日本则将饮茶变为俨然清规;中国茶文化是雅俗共赏的大众文化,日本茶文化则是高高在上的仪式文化。     

墓券与东汉民众的生死观念

东汉时期的世俗民众没有认识到人终有一死的本质特性,反而抗拒死亡,渴求长寿永生。当年寿久长的愿望破灭时,他们又深信异象生命自然会在幽界冥府绵延不绝。不过生者却刻意疏远逝者,直接把殁亡人遣送到彼岸世界,希求幽鬼永居墓穴,接受冥府行政官僚体制和宗族观念的管制和束缚,按照世人的要求和期望去经历冥府生活。     

中国梦科学内涵的三个层次

中国梦的科学内涵具有丰富的思想内容和严密的逻辑结构,分为三个层次:第一个层次是其基本内涵,将国家、民族、个人相结合,赋予不同层次的内涵和追求,即国家富强、民族振兴、人民幸福。中国梦第二层次表现在逻辑结构上:将中国的发展置于历史、现在、未来的时空坐标中,从历史长河探寻发展的规律,从世界层面来看追求的是和谐、和平、合作、共赢,从国家层面要求处理好国家、民族与个人的关系,个人层面强调个体的责任担当。中国梦第三层次体现的是其精神实质,即将中国、世界、人类发展相结合,阐释了中国、世界和人类的关系,将共产主义、中国特色社会主义、人类社会发展相结合,深刻揭示人类社会发展规律。中国梦的本质就是中国特色社会主义。     

Translating Spirituality: Universalism and Particularism in the Diffusion of Spiritual Care from the United States to Israel

Research on the transnational diffusion of ideas and practices shows how cultural objects go through translation, adaptation, and vernacularization when implemented in new localities. Less attention is given to the translators themselves and their heterogeneous and often conflicting visions. Drawing on the notion of transnational social fields (TSF s), this article investigates how cultural objects get vernacularized differently in different parts of the TSF , demonstrating how processes of translation reflect larger social and political struggles over questions of identity. As a case study, we focus on the attempt of actors from Israel and the United States to institutionalize spiritual care in Israeli health‐care organizations. The analysis reveals how spiritual care functioned as a porous cultural object, open to a wide range of interpretations and debates. While actors in New York saw in spiritual care the opportunity to bridge to Israeli Jews and create a global Jewish identity, Israeli actors split between using spiritual care as a vehicle for creating a local Israeli Jewish identity and seeing in spiritual care the opportunity to establish universal identities, broader than the Jewish one. The disagreement and conflicts between the groups influenced the translation process, turning it into a contentious struggle that involved different positions on the continuum between particularism and universalism.