血清胱蛋白酶抑制剂C在老年2型糖尿病患者早期肾功能损害诊断中的价值

目的探讨血清胱蛋白酶抑制剂C（CysC）在老年2型糖尿病患者早期肾功能损害诊断中的价值。方法将45例平均年龄83岁2型糖尿病住院患者,采用胶乳增强免疫比浊法检测血清胱蛋白酶抑制剂C,同时检测血清肌酐（Scr）、血清尿素氮（Bun）、尿肌酐（Ucr）,β2微球蛋白（β2-MG）,推算肌酐清除率（Ccr）,比较两组患者Bun、Scr、Ccr、CysC、β2-MG,两组各检验方法阳性率结果比较。结果两组患者Bun、Scr、Ccr、CysC、β2-MG之间有统计学差异（P〈0．01）;在糖尿病组,CysC法阳性率为55．5％,Ccr法阳性率为86．7％,β2-MG法为60％（P〈0．001）,CysC法与β2-MG法阳性率接近。CysC与Scr、Ccr、β2-MG的相关性分析有统计学意义。结论CysC能够及早发现糖尿病肾病患者肾功能的变化,对其早期的诊断有意义,是一个有价值的指标。     

基于单片机的温湿度检测系统设计简

以STC89C52RC单片机为中心控制器件,设计了温湿度检测系统,系统包括温度传感模块、湿度传感器、单片机编程模块、显示模决、控制模决五部分.该系统可以实时采集工厂环境中的温度和湿度,并将具体的数据显示在液晶显示屏上.系统具有结构简单,使用方便,温湿度检测灵活、精确等优点.     

基于4C理论的旅游纪念品开发研究

对旅游纪念品开发过程中市场开发的程度及管理中面临的问题进行了研究,为提高旅游纪念品开发的有效性和针对性,紧密结合市场需求,基于营销4C理论,分析了旅游纪念品开发的核心要素,提出基于4C理论的旅游纪念品新的开发模式——从推式营销向拉式营销的转变,从产品为主导向消费者为主导转变,并充分发挥政府规划、设计创新、人才培养的支撑作用,打造有竞争力的具备明显区域特色的旅游纪念品。     

人民政协在利益协调机制中的独特地位和作用

人民政协是发扬社会主义民主的重要形式,这就决定了它在完善社会利益协调机制中具有重要的地位。作为中国上层建筑的重要组成部分,人民政协必须也可以适应经济基础的发展,在完善利益诉求表达机制、利益政策整合机制、利益观念引导机制、利益冲突化解机制、利益实现与保障机制中,发挥独特作用。     

Models for the analysis of C-reactive protein in statin trials

Elevation in C-reactive protein (CRP) is an independent risk factor for cardiovascular disease progression and levels are reduced by treatment with statins. However, on-treatment CRP, given baseline CRP and treatment, is not normally distributed and outliers exist even when transformations are applied. Although classical non-parametric tests address some of these issues, they do not enable straightforward inclusion of covariate information. The aims of this study were to produce a model that improved efficiency and accuracy of analysis of CRP data. Estimation of treatment effects and identification of outliers were addressed using controlled trials of rosuvastatin. The robust statistical technique of MM-estimation was used to fit models to data in the presence of outliers and was compared with least-squares estimation. To develop the model, appropriate transformations of the response and baseline variables were selected. The model was used to investigate how on-treatment CRP related to baseline CRP and estimated treatment effects with rosuvastatin. On comparing least-squares and MM-estimation, MM-estimation was superior to least-squares estimation in that parameter estimates were more efficient and outliers were clearly identified. Relative reductions in CRP were higher at higher baseline CRP levels. There was also evidence of a dose-response relationship between CRP reductions from baseline and rosuvastatin. Several large outliers were identified, although there did not appear to be any relationships between the incidence of outliers and treatments. In conclusion, using robust estimation to model CRP data is superior to least-squares estimation and non-parametric tests in terms of efficiency, outlier identification and the ability to include covariate information.     

Inference of non-centrality parameter of a truncated non-central chi-squared distribution

Non-central chi-squared distribution plays a vital role in statistical testing procedures. Estimation of the non-centrality parameter provides valuable information for the power calculation of the associated test. We are interested in the statistical inference property of the non-centrality parameter estimate based on one observation (usually a summary statistic) from a truncated chi-squared distribution. This work is motivated by the application of the flexible two-stage design in case–control studies, where the sample size needed for the second stage of a two-stage study can be determined adaptively by the results of the first stage. We first study the moment estimate for the truncated distribution and prove its existence, uniqueness, and inadmissibility and convergence properties. We then define a new class of estimates that includes the moment estimate as a special case. Among this class of estimates, we recommend to use one member that outperforms the moment estimate in a wide range of scenarios. We also present two methods for constructing confidence intervals. Simulation studies are conducted to evaluate the performance of the proposed point and interval estimates.     

建国初期毛泽东人民政协思想的伟大意义

中国人民政治协商会议是中国共产党领导的统一战线组织.毛泽东不仅亲自组织、领导建立了人民政协,而且在长期领导和指导政协工作的过程中,科学地阐明了人民政协的性质、确立了人民政协的基本职能、培育了人民政协的优良作风.     

C2C市场上消费者从众决策研究——基于面板数据模型

电子商务市场蓬勃发展的同时,也存在严重的信息不对称现象,给消费者带来极大的购物风险。文章基于信息不对称理论,利用淘宝网交易数据对 C2C 市场上消费者的从众决策行为进行研究。研究发现 C2C 市场上店铺的日销量在店铺间存在二八分布的特征,说明网络消费者在购买商品时有从众行为。基于面板模型对店铺市场份额的研究表明,店铺历史销量信息对消费者选择店铺的决策有显著正向影响,而店铺信用对消费者决策的影响并不显著。因此,建议 C2C 交易平台增加退货量指标、动态销量图以及销量和价格的相互对应信息等,以促进消费者理性购物。     

Exponentially weighted moving average charts for correlated multivariate Poisson processes

In this article, we study exponentially weighted moving average (EWMA) control schemes to monitor the multivariate Poisson distribution with a general covariance structure, so that the practitioner can simultaneously monitor multiple correlated attribute processes more effectively. The statistical performance of the charts is assessed in terms of the run length properties and compared against other mainstream attribute control schemes. The application of the proposed methods to real-life and simulated datasets is demonstrated.