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71.
We propose a new class of time dependent random probability measures and show how this can be used for Bayesian nonparametric inference in continuous time. By means of a nonparametric hierarchical model we define a random process with geometric stick-breaking representation and dependence structure induced via a one dimensional diffusion process of Wright-Fisher type. The sequence is shown to be a strongly stationary measure-valued process with continuous sample paths which, despite the simplicity of the weights structure, can be used for inferential purposes on the trajectory of a discretely observed continuous-time phenomenon. A simple estimation procedure is presented and illustrated with simulated and real financial data.  相似文献   
72.
Many disease processes are characterized by two or more successive health states, and it is often of interest and importance to assess state-specific covariate effects. However, with incomplete follow-up data such inference has not been satisfactorily addressed in the literature. We model the logarithm-transformed sojourn time in each state as linearly related to the covariates; however, neither the distributional form of the error term nor the dependence structure of the states needs to be specified. We propose a regression procedure to accommodate incomplete follow-up data. Asymptotic theory is presented, along with some tools for goodness-of-fit diagnostics. Simulation studies show that the proposal is reliable for practical use. We illustrate it by application to a cancer clinical trial.  相似文献   
73.
佛教的"众生平等"思想及其现代意义   总被引:2,自引:0,他引:2  
在对平等的认识上,佛教主张宇宙万物本质上的平等,即"众生平等",包括人与人之间平等、有情众生之间平等、有情众生与无情众生之间平等."众生平等"的理论依据是佛教的缘起理论,其实现途径可从国家、团体、个人三方面入手."众生平等"思想对维护世界和平、保护生态环境及完善人格具有重要意义.  相似文献   
74.
In this article, asymptotic confidence intervals (CIs) for the Sortino and Omega ratios are proposed and analyzed. First, the CIs are derived under the assumption of temporal independence and identical distribution of returns. Later they are obtained assuming that the returns process is strictly stationary and α-mixing of a certain size. In order to evaluate the minimum sample size for a good coverage accuracy of the asymptotic CIs, a simulation study is performed. It is obtained that the minimum sample sizes are very high, especially under the more realistic assumption of not-iid returns.  相似文献   
75.
Motivated by applications in call center management, we propose a framework based on empirical process techniques for inference about waiting time and patience distributions in multiserver queues with abandonment. The framework rigorises heuristics based on survival analysis of independent and identically distributed observations by allowing correlated waiting times. Assuming a regenerative structure of offered waiting times, we establish asymptotic properties of estimators of limiting distribution functions and derived functionals. We discuss construction of bootstrap confidence intervals and statistical tests, including a simple bootstrap two-sample test for comparing patience distributions. A small simulation study and a real data example are presented.  相似文献   
76.
Summary. We use a multipath (multistate) model to describe data with multiple end points. Statistical inference based on the intermediate end point is challenging because of the problems of nonidentifiability and dependent censoring. We study nonparametric estimation for the path probability and the sojourn time distributions between the states. The methodology proposed can be applied to analyse cure models which account for the competing risk of death. Asymptotic properties of the estimators proposed are derived. Simulation shows that the methods proposed have good finite sample performance. The methodology is applied to two data sets.  相似文献   
77.
We consider tests for scale parameters when the underlying distribution belongs to the class of spherically symmetric laws. A (nx1) random vector x has a spherically symmetric distribution if the distribution of x is identical to the distribution of Px for all (n×n) orthogonal matrices P. Using the principle of invariance we show that the usual normal-theory tests are not only invariant tests but are also exactly robust with respect to this class of spherically symmetric laws.  相似文献   
78.
This article considers the constant stress accelerated life test for series system products, where independent log-normal distributed lifetimes are assumed for the components. Based on Type-I progressive hybrid censored and masked data, the expectation-maximization algorithm is applied to obtain the estimation for the unknown parameters, and the parametric bootstrap method is used for the standard deviation estimation. In addition, Bayesian approach combining latent variable with Gibbs sampling is developed. Further, the reliability functions of the system and components are estimated at use stress level. The proposed method is illustrated through a numerical example under different masking probabilities and censoring schemes.  相似文献   
79.
The competing risks model is useful in settings in which individuals/units may die/fail for different reasons. The cause specific hazard rates are taken to be piecewise constant functions. A complication arises when some of the failures are masked within a group of possible causes. Traditionally, statistical inference is performed under the assumption that the failure causes act independently on each item. In this paper we propose an EM-based approach which allows for dependent competing risks and produces estimators for the sub-distribution functions. We also discuss identifiability of parameters if none of the masked items have their cause of failure clarified in a second stage analysis (e.g. autopsy). The procedures proposed are illustrated with two datasets.  相似文献   
80.
Flexible regression is a traditional motivation for the development of non-parametric Bayesian models. A popular approach for this involves a joint model for responses and covariates, from which the desired result arises by conditioning on the covariates. Many such models involve the convolution of a continuous kernel with some discrete random probability measure defined as an infinite mixture of i.i.d. atoms. Following this strategy, we propose a flexible model that involves the concept of repulsion between atoms. We show that this results in a more parsimonious representation of the regression than the i.i.d. counterpart. The key aspect is that repulsion discourages mixture components that are near each other, thus favouring parsimony. We show that the conditional model retains the repulsive features, thus facilitating interpretation of the resulting flexible regression, and with little or no sacrifice of model fit compared to the infinite mixture case. We show the utility of the methodology by way of a small simulation study and an application to a well-known data set.  相似文献   
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