Estimation of Slope for Linear Regression Model with Uncertain Prior Information and Student-t Error

This article considers estimation of the slope parameter of the linear regression model with Student-t errors in the presence of uncertain prior information on the value of the unknown slope. Incorporating uncertain non sample prior information with the sample data the unrestricted, restricted, preliminary test, and shrinkage estimators are defined. The performances of the estimators are compared based on the criteria of unbiasedness and mean squared errors. Both analytical and graphical methods are explored. Although none of the estimators is uniformly superior to the others, if the non sample information is close to its true value, the shrinkage estimator over performs the rest of the estimators.     

Bayesian Analysis of Multiple Hypothesis Testing with Applications to Microarray Experiments

Recently, the field of multiple hypothesis testing has experienced a great expansion, basically because of the new methods developed in the field of genomics. These new methods allow scientists to simultaneously process thousands of hypothesis tests. The frequentist approach to this problem is made by using different testing error measures that allow to control the Type I error rate at a certain desired level. Alternatively, in this article, a Bayesian hierarchical model based on mixture distributions and an empirical Bayes approach are proposed in order to produce a list of rejected hypotheses that will be declared significant and interesting for a more detailed posterior analysis. In particular, we develop a straightforward implementation of a Gibbs sampling scheme where all the conditional posterior distributions are explicit. The results are compared with the frequentist False Discovery Rate (FDR) methodology. Simulation examples show that our model improves the FDR procedure in the sense that it diminishes the percentage of false negatives keeping an acceptable percentage of false positives.     

Hidden Markov Mixture Autoregressive Models: Stability and Moments

This article introduces a parsimonious structure for mixture of autoregressive models, where the weighting coefficients are determined through latent random variables, as functions of all past observations. These latent variables follow a Markov model. We propose a dynamic programming algorithm for forecasting, which reduces the volume of calculations. We also derive limiting behavior of unconditional first moment of the process and an appropriate upper bound for the limiting value of the variance. Further more, we show convergence and stability of the second moment. Finally, we illustrate the efficacy of the proposed model by simulation.     

Estimation of the mixtures of GLMs with covariate-dependent mixing proportions

ABSTRACT

In this article, we study the estimation for a class of semiparametric mixtures of generalized linear models where mixing proportions depend on a covariate non parametrically. We investigate a backfitting estimation procedure and show the asymptotic normality of the proposed estimators under mild conditions. We conduct simulation to show the good performance of our methodology and give a real data analysis as an illustration.     

Bayesian Estimation Using Warner's Randomized Response Model through Simple and Mixture Prior Distributions

The linear discriminant function (LDF) is known to be optimal in the sense of achieving an optimal error rate when sampling from multivariate normal populations with equal covariance matrices. Use of the LDF in nonnormal situations is known to lead to some strange results. This paper will focus on an evaluation of misclassification probabilities when the power transformation could have been used to achieve at least approximate normality and equal covariance matrices in the sampled populations for the distribution of the observed random variables. Attention is restricted to the two-population case with bivariate distributions.     

Trajectory Modeling of Longitudinal Binary Data: Application of the EM Algorithm for Mixture Models

A developmental trajectory describes the course of behavior over time. Identifying multiple trajectories within an overall developmental process permits a focus on subgroups of particular interest. We introduce a framework for identifying trajectories by using the Expectation-Maximization (EM) algorithm to fit semiparametric mixtures of logistic distributions to longitudinal binary data. For performance comparison, we consider full maximization algorithms (PROC TRAJ in SAS), standard EM, and two other EM-based algorithms for speeding up convergence. Simulation shows that EM methods produce more accurate parameter estimates. The EM methodology is illustrated with a longitudinal dataset involving adolescents smoking behaviors.     

An Alternative Estimation Approach for the Heterogeneity Linear Mixed Model

In this article, an alternative estimation approach is proposed to fit linear mixed effects models where the random effects follow a finite mixture of normal distributions. This heterogeneity linear mixed model is an interesting tool since it relaxes the classical normality assumption and is also perfectly suitable for classification purposes, based on longitudinal profiles. Instead of fitting directly the heterogeneity linear mixed model, we propose to fit an equivalent mixture of linear mixed models under some restrictions which is computationally simpler. Unlike the former model, the latter can be maximized analytically using an EM-algorithm and the obtained parameter estimates can be easily used to compute the parameter estimates of interest.     

Bayesian analysis for heteroscedastic normal-Pareto mixture model with application

ABSTRACT

In this article, we propose a new distribution by mixing normal and Pareto distributions, and the new distribution provides an unusual hazard function. We model the mean and the variance with covariates for heterogeneity. Estimation of the parameters is obtained by the Bayesian method using Markov Chain Monte Carlo (MCMC) algorithms. Proposal distribution in MCMC is proposed with a defined working variable related to the observations. Through the simulation, the method shows a dependable performance of the model. We demonstrate through establishing model under a real dataset that the proposed model and method can be more suitable than the previous report.