Megalomania: A Mingled Tale

Predictably, certain patients present treatment issues which resonate strongly with issues that are still problematic (unconscious and/or only partially resolved) for the therapist. This paper examines the author's professional/personal development over forty years, beginning with reflections about a countertransference enactment triggered by an acting-out African American child whose father, his primary caregiver, had abandoned him at age 18 months. The potential dangers and benefits of therapist grandiosity are also considered.     

SoC软硬件协同技术的FPGA芯片测试新方法

针对传统的基于纯硬件平台的FPGA芯片测试方法所存在的种种问题,提出并验证了一种基于软硬件协同技术的FPGA芯片测试方法。该方法引入了软件的灵活性与可观测性等软件技术优势,具有存储深度大、可测I/O管脚数目多、自动完成配置下载(不需人工干预)和自动定位FPGA中的错误等优点,提高了FPGA的测试速度和可靠性,并降低了测试成本,与传统的自动测试仪(ATE)相比有较高的性价比。采用软硬件协同方式针对Xilinx4010的I/O单元进行了测试,实现了对FPGA芯片的自动反复配置、测试和错误定位。     

Female Sex Trade Workers,Condoms, and the Public-Private Divide

Abstract

This qualitative study explored the ways in which social relations within the public (work) as opposed to the private (home) contexts shape variable condom use among female sex trade workers. Semi-structured interviews were conducted with 68 female sex workers working in various settings in an urban center in Eastern Canada. The findings suggest that work-related social relations, and the meanings associated with condoms at work, create a strong confidence in condom use. Within the private setting, such confidence was also evident but most women reported either not using condoms or only using “sometimes.” Nevertheless, many women do engage in risk management within the private setting, and take active steps to decrease their risks of Human Immunodeficiency Syndrome (HIV)/Sexually Transmitted Infections (STIs).     

A Quality Risk Management Model Approach for Cell Therapy Manufacturing

International regulatory authorities view risk management as an essential production need for the development of innovative, somatic cell‐based therapies in regenerative medicine. The available risk management guidelines, however, provide little guidance on specific risk analysis approaches and procedures applicable in clinical cell therapy manufacturing. This raises a number of problems. Cell manufacturing is a poorly automated process, prone to operator‐introduced variations, and affected by heterogeneity of the processed organs/tissues and lot‐dependent variability of reagent (e.g., collagenase) efficiency. In this study, the principal challenges faced in a cell‐based product manufacturing context (i.e., high dependence on human intervention and absence of reference standards for acceptable risk levels) are identified and addressed, and a risk management model approach applicable to manufacturing of cells for clinical use is described for the first time. The use of the heuristic and pseudo‐quantitative failure mode and effect analysis/failure mode and critical effect analysis risk analysis technique associated with direct estimation of severity, occurrence, and detection is, in this specific context, as effective as, but more efficient than, the analytic hierarchy process. Moreover, a severity/occurrence matrix and Pareto analysis can be successfully adopted to identify priority failure modes on which to act to mitigate risks. The application of this approach to clinical cell therapy manufacturing in regenerative medicine is also discussed.     

从货币职能面分析我国M2/GDP的偏高现象

本文将主要从M2/GDP的两种增长方式和货币的五个基本职能出发,结合货币经济和实体经济的发展,总结我国M2/GDP偏高的原因,货币的僵化和低能是最重要的两个方面,并由此给出相应的政策建议.     

Social Competence in Preschool Children: Replication of Results and Clarification of a Hierarchical Measurement Model

This study tested assumptions and conclusions reached in an earlier confirmatory factor analysis (CFA) study of the social competence (SC) construct for preschool children. Two samples (total N = 408; a new Portuguese sample and one from US samples that had participated in the original study) contributed data. Seven SC indicators were tested for mean differences across age, sex, and sample. Significant sex differences were found for peer acceptance (favoring girls) and for initiating affectively neutral interactions (boys had higher rates), and the sex by sample interaction also was significant for initiating interactions (i.e., effect significant only in the Portuguese sample). In CFAs, the hypothesized structure of SC fits the data and was invariant across sample and age within sample in both measurement and structural tests. The model was invariant at the measurement level for sex within sample tests, but not at the structural level. The results replicate and extend understandings of SC reported in the original study.     

The Effects of Participation Rate on the Internal Reliability of Peer Nomination Measures

Although low participation rates have historically been considered problematic in peer nomination research, some researchers have recently argued that small proportions of participants can, in fact, provide adequate sociometric data. The current study used a classical measurement perspective to investigate the internal reliability (Cronbach's α) of peer nomination measures of acceptance, popularity, friendship, prosocial behavior, and overt aggression. Data from 642 participants attending 10 schools were resampled at different participation rates ranging from 5 percent to 100 percent of the original samples. Results indicated that (1) the association between participation rate and Cronbach's α was curvilinear across schools and variables; (2) collecting more data for a given variable (by using unlimited vs. limited nominations, or two vs. one items) was significantly related to higher internal reliability; and (3) certain variables (overt aggression, popularity) were more reliable than others (acceptance, friendship). Implications for future research were discussed.     

Associations among Maternal Behavior,Delay of Gratification,and School Readiness across the Early Childhood Years

This study examined the developmental pathways from maternal behavior to school readiness within a sample of 1007 children, with a specific focus on the mediating role of delay of gratification (DoG). Maternal behavior across the first 36 months of age was explored as a predictor of children's DoG at 54 months as well as their behavioral and academic competence in kindergarten. Results support sensitivity as a predictor of children's DoG and indicate significant associations between DoG and teacher‐reported externalizing behavior, social skills, and academic skills. Moreover, DoG partially mediated the associations between maternal sensitivity and school readiness skills, with the highest percentage of mediation reported for social skills. Findings indicate maternal sensitivity and DoG as potential targets for efforts aimed at enhancing school readiness among young children.     

Estimation of the mean of the exponential distribution with an outlying observation

Given a life testing experiment consisting of n items, n-1 of which have the expected life λ while one could have an expected life λ/α with 0 < α < 1 the problem is. to find a mean square error (MSE) minimizing estimation function. The standard estimators for the homogeneous case (α = 1) overestimate the expected life and their MSE tend to infinity when a tends to 0.

Looking at the estimation problem as an insurance (see Anscombe (1960)) two different “testimators” are compared with respect to their MSE, Numerical results show that an estimation function based on the “Epstein-statistic” x_(n)/[xbar] is the best one.     

Overdispersed negative binomial regression models

Overdispersion is a common phenomenon in actual data sets. It is important to have methods of dealing with extra variation in regression situations. This article develops tests for extra-negative binomial variation and gives some numerical methods to deal with it. Simulations show power comparisons between some of the overdispersion tests discussed. Finally, an example is given to demonstrate the methods.