Goodness of fit for thei ordered categories discrete uniform distribution

Goodness of fit for thei ordered categories discrete uniform distribution can be carried out using Pearson's X² _pstatistic and its components. Applications of this technique are considered and comparisons made with recently suggested empirical uniform distribution     

骨形成过程中两条重要的信号传导通路

Wnt信号通路与BMP-2信号通路能够促进成骨细胞的分化和成骨细胞分泌的胞外基质的生物矿化,在这一过程中起着极其重要的作用.本文主要综述了,近年来对这两条信号通路研究的最新进展.     

Four tests of fit for the beta-binomial distribution

Tests based on the Anderson–Darling statistic, a third moment statistic and the classical Pearson–Fisher X ² statistic, along with its third-order component, are considered. A small critical value and power study are given. Some examples illustrate important applications.     

Constructing identity with L2: Pronunciation and attitudes among Norwegian learners of English1

This study investigates L2 pronunciation and evaluation of American and British varieties of English among Norwegian adolescent learners. By integrating quantitative sociolinguistics and L2 acquisition, the article investigates stylistic practice in an L2 context. Results from an auditory analysis of four phonological variables and a matched‐guise test are interpreted with reference to speaker commentary. Learners’ self‐expressed accent aims correlate significantly with accent use, but American English is the dominant pronunciation. Results show that both L1 and L2 speakers of English varieties are socially evaluated by the learners; British English is considered the most prestigious model of pronunciation, while American English is associated with informality. These evaluations seem to motivate learners’ pronunciation choices. The data indicate blended use of the English varieties. Learners seem to exploit linguistic resources from English, and reshape and adapt the social meaning of the variables to a local construction of identity.     

Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men

Abstract

Estradiol (E2) is, apart from its role as a reproductive hormone, also important for cardiac function and bone maturation in both genders. It has also been shown to play a role in insulin production, energy expenditure and in inducing lipolysis. The aim of the study was to investigate if low circulating testosterone or E2 levels in combination with variants in the estrogen receptor alpha (ESR1) and estrogen receptor beta (ESR2) genes were of importance for the risk of type-2 diabetes. The single nucleotide polymorphisms rs2207396 and rs1256049, in ESR1 and ESR2, respectively, were analysed by allele specific PCR in 172 elderly men from the population-based Tromsø study. The results were adjusted for age. In individuals with low total (≤11?nmol/L) or free testosterone (≤0.18?nmol/L) being carriers of the variant A-allele in ESR1 was associated with 7.3 and 15.9 times, respectively, increased odds ratio of being diagnosed with diabetes mellitus type 2 (p?=?0.025 and p?=?0.018, respectively). Lower concentrations of E2 did not seem to increase the risk of being diagnosed with diabetes. In conclusion, in hypogonadal men, the rs2207396 variant in ESR1 predicts the risk of type 2 diabetes.     

3-状态部分2-树网络可靠度的一个多项式时间算法

本文利用3-状态设备网络可靠度计算归约公式,结合Wald.J.A.-Colbourn C.J.[1]算法(简称为W-C算法2),给出了3-状态部分2-树网络可靠度的一个多项式时间算法.     

White and nonwhite trends in first birth timing: Comparisons using vital registration and current population surveys

The magnitude of racial differences in first birth timing vary greatly depending upon the data sources from which they are estimated. Vital registration data (Heuser 1976; with updates from the National Center for Health Statistics 1974–1990) show that in recent years nonwhites have higher risks of a first birth at virtually all ages compared to whites. As a result very large and historically novel differentials in childlessness are forecast using these data (see Rindfuss et al. 1988; Chen & Morgan 1991; Morgan & Chen 1992). However, retrospective fertility history data collected from the 1980, 1985 and 1990 Current Population Surveys (CPS) suggest much smaller racial differences in completed childlessness and isolate racial differences in probabilities of first births at young ages. Differences also exist between theses two series for whites prior to the mid-1960s but not afterwards. Reasons for these differing estimates are suggested and examined. We conclude that a substantial portion of the differences result from an accumulation of biases in the vital registration estimates that affect primarily estimates of first birth timing. Thus, the CPS data provide a more firm basis for racial comparisons of first birth timing.     

近三十年新疆高校少数民族汉语教学研究述评

文章对1979年以来发表在新疆主要刊物和区外核心刊物中的423篇高校少数民族汉语教学研究论文进行了统计分析。在30年的发展中其成绩主要表现在研究基础不断扩大、研究论题走向广泛与细化、研究方法有一定的改进。而存在的主要缺憾是研究内容不深入、研究方法单一,定量和定性研究重视不够等问题。目前新疆高校少数民族汉语教育虽然有较大发展,但在教学上过度依赖对外汉语教学,在研究层次上仍处于相对较低的水平。     

Knowledge transfer of the Western concept of quality

This paper addresses one of the issues in contemporary globalization theory: the extent to which there is 'one best way' in which business can be conducted and organizations managed. It uses Czarniawska's 'travels of ideas' model as an organizing framework to present and understand how the concept of 'quality', so important in contemporary approaches to manufacturing and services, and their management, travelled to, and impinged on, a newly opened vehicle assembly plant in Poland. The extent to which new meanings were mutually created in the process of translation is discussed, using ethnographic reporting and analysis techniques commonly used in diffusion research. Parallels between the process of translation as an idea becomes embedded into a new cultural location and the processes which contemporary research has identified as important to organizational learning are briefly discussed in conclusion.     

A cross-validation of a structural equation model of accidents: organizational and psychological variables as predictors of work safety

A study to establish a structural equation model of accidents is presented. The eight variables included in the model were those associated with accidents in previous research. The reliability of questionnaires to measure those variables and a structural equation model relating them are provided. The model explaining the occurrence of accidents was cross-validated through three Spanish samples (n=123; 182; 124).The model presented a good fit to data in two samples, while a third had unclear fit indices. Therefore, most relationships among variables did not vary among these three samples. The role of the safety variables in the model is discussed. The discussion is also focused on risk measurement difficulties commonly reported in the literature. Finally, some suggestions for future safety research with structural equation modelling techniques are provided.