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361.
We consider response adaptive designs when the binary response may be misclassified and extend relevant results in the literature. We derive the optimal allocations under various objectives and examine the relationship between the power of statistical test and the variability of treatment allocation. Asymptotically best response adaptive randomization procedures and effects of misclassification on the optimal allocations are investigated. A real-life clinical trial is also discussed to illustrate our proposed approach. 相似文献
362.
363.
Dean A. Follmann 《统计学通讯:理论与方法》2013,42(10):2775-2795
In the classical growth curve setting, individuals are repeatedly measured over time on an outcome of interest. The objective of statistical modeling is to fit some function of time, generally a polynomial, that describes the outcome's behavior. The polynomial coefficients are assumed drawn from a multivariate normal mixing distribution. At times, it may be known that each individual's polynomial must follow a restricted form. When the polynomial coefficients lie close to the restriction boundary, or the outcome is subject to substantial measurement error, or relatively few observations per individual are recorded, it can be advantageous to incorporate known restrictions. This paper introduces a class of models where the polynomial coefficients are assumed drawn from a restricted multivariate normal whose support is confined to a theoretically permissible region. The model can handle a variety of restrictions on the space of random parameters. The restricted support ensures that each individual's random polynomial is theoretically plausible. Estimation, posterior calculations, and comparisons with the unrestricted approach are provided. 相似文献
364.
The purpose of this paper is to discuss response surface designs for multivariate generalized linear models (GLMs). Such models are considered whenever several response variables can be measured for each setting of a group of control variables, and the response variables are adequately represented by GLMs. The mean-squared error of prediction (MSEP) matrix is used to assess the quality of prediction associated with a given design. The MSEP incorporates both the prediction variance and the prediction bias, which results from using maximum likelihood estimates of the parameters of the fitted linear predictor. For a given design, quantiles of a scalar-valued function of the MSEP are obtained within a certain region of interest. The quantiles depend on the unknown parameters of the linear predictor. The dispersion of these quantiles over the space of the unknown parameters is determined and then depicted by the so-called quantile dispersion graphs. An application of the proposed methodology is presented using the special case of the bivariate binary distribution. 相似文献
365.
颜文杰 《长春理工大学学报(高教版)》2006,(3)
曾经名不见经传的湖北土家掉渣烧饼在一夜之间迅速蹿红,从门庭若市到门可罗雀,掉渣烧饼的命运从一个侧面呈现出目前特许经营已多行业、市场化、国际化的趋势.随着中国加入WTO,市场开放程度的加大,我国特许经营也面临着机遇和挑战。为了加快特许经营的发展,一方面要积极引进、借鉴、吸收国外成功的经验和好的做法;另一方面要结合本地实际情况,探索一条行之有效的特许经营发展新路子。 相似文献
366.
美国社区学院的社区教育及几点思考 总被引:4,自引:0,他引:4
万秀兰 《浙江师范大学学报(社会科学版)》2001,26(6):79-83
本文依次从历史渊源、目的、活动领域、组织形式、经费、规模、发展趋势等方面,对美国社区学院的社区教育进行了比较全面和深入的论述,最后就我国社区教育提出了几点思考意见. 相似文献
367.
惠卫兵 《南京人口管理干部学院学报》2001,17(4):55-56,54
目前在农村实行的税费改革是农村政策的重大调整。农村计划生育工作在税费改革中遇到了机构、人员、经费等诸多问题。作者通过对安徽宣城等地的调查 ,提出了乡镇机构改革、人员分流、财政投入等对策 相似文献
368.
The Northern Territory National Emergency Response Act 2007 was a radical intervention into the lives of Aboriginal residents of the Northern Territory, Australia. One of the intervention's key measures was income management – a scheme designed to limit the range of goods and services that may be purchased with social security payments. The aim of income management was to curb 'anti‐social behaviours' such as excessive gambling and alcohol consumption. In this paper, we specifically test the efficacy of income management in reducing the amount spent on commercial gambling. To achieve this we conduct an interrupted time series analysis with deflated monthly electronic gaming machine (EGM) expenditure data from July 2002 to July 2010 for hotels and clubs in the towns of Alice Springs and Katherine. We find a negative association between income management and EGM revenues for only one gambling venue in each town. However, local complexity in the form of segregated markets along temporal, spatial and racial lines, along with other policy confounders, may obscure the effects of the macro‐policy intervention. We conclude by making suggestions for locally‐based responses to problematic forms of risky consumption that may be more sensitive to local geographies. 相似文献
369.
Standard response surface methodology employs a second order polynomial model to locate the stationary point ξ of the true response function. To make Bayesian analysis more direct and simpler, we refer to an alternative and equivalent parametrization, which contains ξ as parameter of interest. The marginal reference prior of ξ is derived in its general form and particular cases are also given in detail, showing the Bayesian role of rotatability. 相似文献
370.