Covariate Selection for the Semiparametric Additive Risk Model

Abstract.  This paper considers covariate selection for the additive hazards model. This model is particularly simple to study theoretically and its practical implementation has several major advantages to the similar methodology for the proportional hazards model. One complication compared with the proportional model is, however, that there is no simple likelihood to work with. We here study a least squares criterion with desirable properties and show how this criterion can be interpreted as a prediction error. Given this criterion, we define ridge and Lasso estimators as well as an adaptive Lasso and study their large sample properties for the situation where the number of covariates p is smaller than the number of observations. We also show that the adaptive Lasso has the oracle property. In many practical situations, it is more relevant to tackle the situation with large p compared with the number of observations. We do this by studying the properties of the so-called Dantzig selector in the setting of the additive risk model. Specifically, we establish a bound on how close the solution is to a true sparse signal in the case where the number of covariates is large. In a simulation study, we also compare the Dantzig and adaptive Lasso for a moderate to small number of covariates. The methods are applied to a breast cancer data set with gene expression recordings and to the primary biliary cirrhosis clinical data.     

Transformed generalized linear models

The estimation of data transformation is very useful to yield response variables satisfying closely a normal linear model. Generalized linear models enable the fitting of models to a wide range of data types. These models are based on exponential dispersion models. We propose a new class of transformed generalized linear models to extend the Box and Cox models and the generalized linear models. We use the generalized linear model framework to fit these models and discuss maximum likelihood estimation and inference. We give a simple formula to estimate the parameter that index the transformation of the response variable for a subclass of models. We also give a simple formula to estimate the r$r$th moment of the original dependent variable. We explore the possibility of using these models to time series data to extend the generalized autoregressive moving average models discussed by Benjamin et al. [Generalized autoregressive moving average models. J. Amer. Statist. Assoc. 98, 214–223]. The usefulness of these models is illustrated in a simulation study and in applications to three real data sets.     

A copula-based Markov chain model for the analysis of binary longitudinal data

A fully parametric first-order autoregressive (AR(1)) model is proposed to analyse binary longitudinal data. By using a discretized version of a copula, the modelling approach allows one to construct separate models for the marginal response and for the dependence between adjacent responses. In particular, the transition model that is focused on discretizes the Gaussian copula in such a way that the marginal is a Bernoulli distribution. A probit link is used to take into account concomitant information in the behaviour of the underlying marginal distribution. Fixed and time-varying covariates can be included in the model. The method is simple and is a natural extension of the AR(1) model for Gaussian series. Since the approach put forward is likelihood-based, it allows interpretations and inferences to be made that are not possible with semi-parametric approaches such as those based on generalized estimating equations. Data from a study designed to reduce the exposure of children to the sun are used to illustrate the methods.     

On cumulative entropies

In analogy with the cumulative residual entropy recently proposed by Wang et al. [2003a. A new and robust information theoretic measure and its application to image alignment. In: Information Processing in Medical Imaging. Lecture Notes in Computer Science, vol. 2732, Springer, Heidelberg, pp. 388–400; 2003b. Cumulative residual entropy, a new measure of information and its application to image alignment. In: Proceedings on the Ninth IEEE International Conference on Computer Vision (ICCV’03), vol. 1, IEEE Computer Society Press, Silver Spring, MD, pp. 548–553], we introduce and study the cumulative entropy, which is a new measure of information alternative to the classical differential entropy. We show that the cumulative entropy of a random lifetime X can be expressed as the expectation of its mean inactivity time evaluated at X. Hence, our measure is particularly suitable to describe the information in problems related to ageing properties of reliability theory based on the past and on the inactivity times. Our results include various bounds to the cumulative entropy, its connection to the proportional reversed hazards model, and the study of its dynamic version that is shown to be increasing if the mean inactivity time is increasing. The empirical cumulative entropy is finally proposed to estimate the new information measure.     

Collapsibility for Directed Acyclic Graphs

Abstract.  Collapsibility means that the same statistical result of interest can be obtained before and after marginalization over some variables. In this paper, we discuss three kinds of collapsibility for directed acyclic graphs (DAGs): estimate collapsibility, conditional independence collapsibility and model collapsibility. Related to collapsibility, we discuss removability of variables from a DAG. We present conditions for these three different kinds of collapsibility and relationships among them. We give algorithms to find a minimum variable set containing a variable subset of interest onto which a statistical result is collapsible.     

中国通货膨胀率的非线性动态行为研究——来自MS—ARFIMA模型的新证据

使用允许长记忆参数d服从区制转换的MS—ARFIMA模型对中国月度通货膨胀路径的动态行为进行新的实证研究,结果显示：中国通货膨胀不仅均值水平和不确定性存在着“低通胀”区制和“高通胀”区制,而且更为重要的是,通货膨胀序列的平稳性也表现出显著的区制转换动态。“低通胀”区制下,长记忆参数d1=0．361,说明通货膨胀是协方差平稳序列,“高通胀”区制下,长记忆参数d2=1．145,说明通货膨胀是非平稳序列。这一新的研究结论意味着中国通货膨胀冲击的持久性效应也存在相应的区制转移变化。这要求央行在管控通货膨胀过程中,既要考虑均值和不确定性的区制变化,又要兼顾平稳性和持久性的区制变化。     

中国粮食价格波动特征研究——基于X-12-ARIMA模型和ARCH类模型

以小麦和大豆为例,研究2002年1月至2012年6月中国粮食价格波动特征。首先利用X-12-ARIMA模型对价格序列进行季节调整,然后运用ARCH类模型对剥离季节因素的价格序列进行波动分析。结果发现:中国粮食价格季节性波动逐年减弱;粮食价格具有明显的波动集簇性,前期价格波动和外部冲击对后期价格的影响具有持续性;粮食市场不存在"高风险、高回报"特征;小麦价格波动的非对称性不显著,而大豆价格波动则呈现明显的非对称特征,且上期价格上涨信息引发的波动要大于下跌信息。     

基于核和灰度的双重异构数据序列预测建模方法研究

通过建立灰色异构数据"核"序列的DGM(1,1)模型,实现双重异构数据"核"的预测;以"核"为基础、以双重异构数据序列中较大的区间灰数信息域作为预测结果的信息域,构建基于区间灰数与实数的双重异构数据序列灰色预测模型,有效地将灰色预测模型建模对象从"同质数据"拓展至"双重异构数据"。研究成果对丰富灰色预测模型理论体系具有积极意义。     

Statistical inference for partially time-varying coefficient errors-in-variables models

This paper studies the partially time-varying coefficient models where some covariates are measured with additive errors. In order to overcome the bias of the usual profile least squares estimation when measurement errors are ignored, we propose a modified profile least squares estimator of the regression parameter and construct estimators of the nonlinear coefficient function and error variance. The proposed three estimators are proved to be asymptotically normal under mild conditions. In addition, we introduce the profile likelihood ratio test and then demonstrate that it follows an asymptotically χ²${\chi }^2$ distribution under the null hypothesis. Finite sample behavior of the estimators is investigated via simulations too.     

Bayesian inference with misspecified models

This article reviews Bayesian inference from the perspective that the designated model is misspecified. This misspecification has implications in interpretation of objects, such as the prior distribution, which has been the cause of recent questioning of the appropriateness of Bayesian inference in this scenario. The main focus of this article is to establish the suitability of applying the Bayes update to a misspecified model, and relies on representation theorems for sequences of symmetric distributions; the identification of parameter values of interest; and the construction of sequences of distributions which act as the guesses as to where the next observation is coming from. A conclusion is that a clear identification of the fundamental starting point for the Bayesian is described.