Testing a main effect in a three factor mixed model

In the present paper, the author has considered and compared the power of three test procedures, based on two preliminary tests of significance (PTS), for testing a main effect in a three factor factorial experiment. Davenport and Webster (1973) type test statistics are used in the final test. Recommendation for a suitable size of PTS has been made so that the power of a test procedure is adequately high.     

The relative performances of improved ridge estimators and an empirical bayes estimator: some monte carlo results

The relative 'performances of improved ridge estimators and an empirical Bayes estimator are studied by means of Monte Carlo simulations. The empirical Bayes method is seen to perform consistently better in terms of smaller MSE and more accurate empirical coverage than any of the estimators considered here. A bootstrap method is proposed to obtain more reliable estimates of the MSE of ridge esimators. Some theorems on the bootstrap for the ridge estimators are also given and they are used to provide an analytical understanding of the proposed bootstrap procedure. Empirical coverages of the ridge estimators based on the proposed procedure are generally closer to the nominal coverage when compared to their earlier counterparts. In general, except for a few cases, these coverages are still less accurate than the empirical coverages of the empirical Bayes estimator.     

Considerations for optimal nonparametric regression under a generalizederror structure

Nonparametric smoothing, such as kernel or spline estimation, has been examined extensively under the assumption of uncorrelated errors. This paper addresses the effects of potential correlation on consistency and other asymptotic properties in a repeated-measures model, using directly optimized linear smoothers of the replicate means. Unrestricted optimal weights, with respect to squared error loss, are used to confirm a lack of consistency for all linear estimators in an autocorrelated errors model. The results indicate kernel methods that work well for an uncorrelated errors model may not have the ability to perform satisfactorily when correlation is introduced, due to an asymmetry in the optimal weights, which disappears for an uncorrelated errors model. These would include data-driven bandwidth selection methods, adjustments of the bandwidth to accommodate correlation, higher-order kernels, and related bias reduction techniques. The analytic results suggest alternative approaches, not considered here in detail, which have shown merit.     

Comparison of estimators of the location parameter using pitman's closeness criterion

Necessary and sufficient conditions for a linear estimator to dominate another linear estimator of a location parameter under the Pitman's criterion of comparison are discussed. Consequently it is demonstrated that a linear biased estimator can not dominate a linear unbiased estimator under Pitman's criterion and that the sample mean is the Closest Linear Unbiased Estimator (CLUE). It is also shown that the ridge regression estimator with a known biasing constant can not dominate the ordinary least squares estimator. If an estimator δdominates an estimator δin the average loss sense then sufficient conditions are obtained under which δis also preferred over δunder Pitman's criterion. Further we obtain sufficient conditions under which preference under the Pitman's criterion will lead to preference under the mean squared error sense.     

Estimation of the smaller and larger of two exponential location parameters

Assume independent random samples are drawn from two populations which are exponentially distributed with unknown location parameters and a common known scale parameter. We want to estimate the maximum and the minimum of the unknowo location paremeters. In this paper several estimators are proposed which are better than the natural estimations in terms of absolute bias and /or meaqn squared error.     

Empirical bayes shrinkage estimation of reliability in the exponential distribution

In this paper we propose two empirical Bayes shrinkage estimators for the reliability of the exponential distribution and study their properties. Under the uniform prior distribution and the inverted gamma prior distribution these estimators are developed and compared with a preliminary test estimator and with a shrinkage testimator in terms of mean squared error. The proposed empirical Bayes shrinkage estimator under the inverted gamma prior distribution is shown to be preferable to the preliminary test estimator and the shrinkage testimator when the prior value of mean life is clsoe to the true mean life.     

Alternative covariance estimates in a replicated measurement error model with correlated,heteroscedastic errors

The article concerns covariance estimates in a replicated measurement error model with correlated, heteroscedastic errors. Freedman has conjectured that using more of the data will improve estimates of covariance matrices and result in a more efficient estimate of the coefficient of the regression model. The paper confirms the conjecture asymptotically for the case that all random variables are normally distributed, but the gain is not substantial.     

Correlation in a Bayesian framework

The authors consider the correlation between two arbitrary functions of the data and a parameter when the parameter is regarded as a random variable with given prior distribution. They show how to compute such a correlation and use closed form expressions to assess the dependence between parameters and various classical or robust estimators thereof, as well as between p‐values and posterior probabilities of the null hypothesis in the one‐sided testing problem. Other applications involve the Dirichlet process and stationary Gaussian processes. Using this approach, the authors also derive a general nonparametric upper bound on Bayes risks.     

Tolerance‐based error reduction in multi‐agent bioassays

Some degree of error is inevitable in multi‐agent bioassays regardless of design or measurement technology. Estimation error can be reduced post facto by exploiting the matrix partial ordering of the bioassay survival estimates. The standard method for this is order‐restricted regression (ORR). If the joint action of the bioassay agents admits a tolerance‐based interpretation, additional structure beyond matrix partial ordering is available, leading to a new method of error reduction. This tolerance‐based error reduction (TBER) procedure almost always outperforms ORR. Like ORR, TBER applies to complete factorial bioassay designs and, using weighting, to incomplete designs.     

SEMIPARAMETRIC REGRESSION AND GRAPHICAL MODELS

Semiparametric regression models that use spline basis functions with penalization have graphical model representations. This link is more powerful than previously established mixed model representations of semiparametric regression, as a larger class of models can be accommodated. Complications such as missingness and measurement error are more naturally handled within the graphical model architecture. Directed acyclic graphs, also known as Bayesian networks, play a prominent role. Graphical model-based Bayesian 'inference engines', such as bugs and vibes , facilitate fitting and inference. Underlying these are Markov chain Monte Carlo schemes and recent developments in variational approximation theory and methodology.