A Bayesian HMM with random effects and an unknown number of states for DNA copy number analysis

Hidden Markov models (HMMs) have been shown to be a flexible tool for modelling complex biological processes. However, choosing the number of hidden states remains an open question and the inclusion of random effects also deserves more research, as it is a recent addition to the fixed-effect HMM in many application fields. We present a Bayesian mixed HMM with an unknown number of hidden states and fixed covariates. The model is fitted using reversible-jump Markov chain Monte Carlo, avoiding the need to select the number of hidden states. We show through simulations that the estimations produced are more precise than those from a fixed-effect HMM and illustrate its practical application to the analysis of DNA copy number data, a field where HMMs are widely used.     

Statistical properties of Rechtschaffner designs

Rechtschaffner designs are saturated designs of resolution V   in which main effects and two-factor interactions are estimable if three-factor and higher order interactions are negligible. Statistical properties of Rechtschaffner designs are studied in this paper. Best linear unbiased estimators of main effects and two-factor interactions are given explicitly and asymptotic properties of correlations between these estimators are studied as well. It is shown that designs recommended by Rechtschaffner [1967. Saturated fractions of 2ⁿ$2^n$ and 3ⁿ$3^n$ factorial designs, Technometrics 9, 569–576] are not only A-optimal but also D-optimal. Comparisons of Rechtschaffner designs with other A- and D-optimal designs of resolution V are also discussed.     

水泥土粉喷桩桩身质量试验研究

分析了苏北沿海地区(盐城、连云港)典型软土层中粉喷桩桩身质量的测试方法和结果.用标准贯入试验和现场取芯试验可以有效地检测粉喷桩桩身强度和主要影响因素;用低应变动测试验可以对粉喷桩实施普查,即对粉喷桩桩身的完整性做出合理的评价.提出将粉喷桩桩身强度与完整性测试结合起来,从而对粉喷桩桩身质量做出较全面的评价,为该地区粉喷桩复合地基的推广应用提供依据.     

粉喷桩设计工程实例剖析

通过粉喷桩处理软土地基工程实例,剖析粉喷桩设计方法,分析粉喷桩的优点,探索粉喷桩复合地基优化设计方法.     

用于DVD的MPEG2实时解复用器的FPGA设计与实现

设计了一种模块化,内部采用总线形式,用于ＤＶＤ的ＭＰＥＧ２系统层实时解复用器,并对电路的总体结构、起始头检测电路、ＰＥＳ包头解码电路和ＰＬＬ电路作了详细的介绍和讨论,给出了整个实时解复用器的ＦＰＧＡ硬件实现结果。该系统具有基本流多路分配、系统时钟恢复的功能,同时又有结构简单、耗用资源少和易于集成等特点,适于 ＤＶＤ及相关领域的应用。     

基于数据阵共轭重构的MUSIC角估计算法

介绍了一种利用接收数据及其共轭重构得到新的数据矩阵,然后借助于数据阵奇异值分解实现的修正MUSIC算法,并指出了这将有助于改善协方差矩阵特征值的分布,从而提高信号到达方向（DOA）的估计性能。在相同的信噪比和快拍数条件下,该方法无论是在角估计的均方误差、信号源角分辨能力等方面均优于普通的MUSIC算法,并给出了验证理论分析的计算机仿真结果。     

粉喷桩复合地基在建筑工程中的应用探讨

根据工程实践及有关测试资料分析、探讨了水泥土粉喷极的工程特性及其在本地区建筑工程中的应用实例。     

PIN结构自扫描光电二极管列阵的理论分析及实验研究

提出了用PIN结构代替通用的PN结结构组成自扫描光电二极管列阵(SSPA)的构想,并从理论上推导了再充电采样的SSPA性能参数的一般表达式。由此推断出PIN结构SSPA具有高响应度高分辨率的特点。实验上制备出了不同光敏面积的PIN结构SSPA,并和相同面积的PN结结构SSPA比较。结果表明前者优于后者,与理论预期相一致。     

大空间建筑居留区空调射流与室内羽状气流作用机理研究

在建立非等温射流运动的物理方程时,考虑由室内热源形成的羽状气流对射流运动的热浮升作用力,得到受羽状气流作用的射流运动轨迹表达式.经现场实测验证后,上述理论分析认为,空调射流与羽状气流的相互作用会影响射流轨迹,且在一定程度上改变其运行轨迹.