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261.
Tests based on rank statistics are introduced to test for systematic changes in a sequence of independent observations. Proposed tests include a rank test analogous to the parametric likelihood ratio test and others analogous to parametric Bayes tests. The tests are usable with either one- or two-sided alternative hypotheses, and their asymptotic distributions are studied. The results of the general model are applied to two special cases, and their asymptotic distributions are also investigated. A Monte Carlo study verifies the applicability of asymptotic critical points in samples of moderate size, and other simulation studies compare power of the competing tests and their special-case versions. Finally, these tests are applied to a data set of traffic fatalities.  相似文献   
262.
Abstract

Under an incomplete block crossover design with two periods, we derive the least-squares estimators for the period effect, treatment effects and carry-over effects in explicit formulae based on within-patient differences. Using the commonly-used strategy of searching a base model for making inferences in regression analysis, we define a two-stage test procedure in studying treatment effects. On the basis of Monte Carlo simulation, we evaluate the performance of the two-stage procedure for hypothesis testing, point and interval estimation of treatment effects in a variety of situations. We note that use of the two-stage procedure can be potentially misleading and hence one should not apply a test procedure to exclusively determine whether he/she needs to account for the carry-over effect in studying treatment effects. We use the double-blind crossover trial comparing two different doses of formoterol with placebo on the forced expiratory volume in 1 second (FEV1) readings to illustrate the use of the two-stage procedure, as well as the distinction between use of two-stage procedure and the approach with assuming no carry-over effects based on one's subjective knowledge.  相似文献   
263.
264.
Abstract

A method of construction of A-optimal binary block designs for asymmetrical parallel line assays, i.e., the assays in which the number doses for standard and test preparation are unequal has been considered. The method is illustrated with examples. Two cases of this method have been considered. In the first case, designs obtained are of equal replications of the doses. In the second case, designs with unequal replications are obtained.  相似文献   
265.
This communication deals with the construction and optimality of non-proper (unequal block sized) variance balanced (VB) designs obtainable under linear homoscedastic normal model. Several methods of construction of non-proper VB designs have been given. Some constructed designs are universally optimal non-proper variance balanced designs.  相似文献   
266.
Using a model given by Archbold and Johnson (1958) it is shown that the generalised Room square design is universally optimal for the estimation of the treatment effects. Further, if the variety-block design in a generalised Room square design is a BIBD, this design is also universally optimal for the estimation of the varietal effects.  相似文献   
267.
针对渤南区块"高温"、"高压"及"含膏"特点,研发了聚胺抗高温防塌钻井液体系,该体系抑制性及封堵性好,抗温、抗盐及抗钙能力强,配合现场钻井液维护处理工艺,取得了良好的现场应用效果,解决了渤南区块复杂地质情况下井壁失稳的难题,为区块施工提供了技术支撑.  相似文献   
268.
要发展城市,必须懂得营销城市。特色是城市形象的基石,街区是城市的基本单元,以特色街区的规划建设促进城市营销,已经成为当今国内外众多城市的经典做法。伟大的城市呼唤伟大的街道,伟大的街道造就伟大的城市。事实上,国内外众多区域中心城市、国家中心城市甚至世界中心城市的崛起之路正是由特色街区的规划建设开始起步的。实践证明,特色街区的规划建设对推动中心城市的整体与长远发展能够产生良好的"乘数效应"。  相似文献   
269.
An algorithm for the construction of a wide class of block designs including Balanced Incomplete Blocks (BIB) is described. The algorithm which allows the experimenter to give weights for a set of treatment contrasts uses an initial starting design to generate an optimal block design sequentially. The performance of the algorithm is illustrated by examples, and designs constructed by the algorithm compare favourably with designs generated by other methods.  相似文献   
270.
在已有的各种算法基础上,利用混合抽点法和广义数论变换,得到一种计算离散傅氏变换的快速算法,该算法由于大大减少了乘法运算而使速度和精度显著提高,在结构上呈模块化的通用结构,具有类似于 FFT 的蝶代运算,易于用硬软件实现,其结构上的递推性使之对较长序列的处理优于其它方法。运用本文的算法在 IBM PC 微机上实现了滤波。该算法还与同类算法进行了比较。  相似文献   
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