Nonparametric and semiparametric estimation of the three way receiver operating characteristic surface

In many situations the diagnostic decision is not limited to a binary choice. Binary statistical tools such as receiver operating characteristic (ROC) curve and area under the ROC curve (AUC) need to be expanded to address three-category classification problem. Previous authors have suggest various ways to model the extension of AUC but not the ROC surface. Only simple parametric approaches are proposed for modeling the ROC measure under the assumption that test results all follow normal distributions. We study the estimation methods of three-dimensional ROC surfaces with nonparametric and semiparametric estimators. Asymptotical results are provided as a basis for statistical inference. Simulation studies are performed to assess the validity of our proposed methods in finite samples. We consider an Alzheimer's disease example from a clinical study in the US as an illustration. The nonparametric and semiparametric modelling approaches for the three way ROC analysis can be readily generalized to diagnostic problems with more than three classes.     

Posterior Analysis for Normalized Random Measures with Independent Increments

Abstract.  One of the main research areas in Bayesian Nonparametrics is the proposal and study of priors which generalize the Dirichlet process. In this paper, we provide a comprehensive Bayesian non-parametric analysis of random probabilities which are obtained by normalizing random measures with independent increments (NRMI). Special cases of these priors have already shown to be useful for statistical applications such as mixture models and species sampling problems. However, in order to fully exploit these priors, the derivation of the posterior distribution of NRMIs is crucial: here we achieve this goal and, indeed, provide explicit and tractable expressions suitable for practical implementation. The posterior distribution of an NRMI turns out to be a mixture with respect to the distribution of a specific latent variable. The analysis is completed by the derivation of the corresponding predictive distributions and by a thorough investigation of the marginal structure. These results allow to derive a generalized Blackwell–MacQueen sampling scheme, which is then adapted to cover also mixture models driven by general NRMIs.     

Darling–Erdős limit results for change-point detection in panel data

We wish to test the null hypothesis if the means of N panels remain the same during the observation period of length T. A quasi-likelihood argument leads to self-normalized statistics whose limit distribution under the null hypothesis is double exponential. The main results are derived assuming that the each panel is based on independent observations and then extended to linear processes. The proofs are based on an approximation of the sum of squared CUSUM processes using the Skorokhod embedding scheme. A simulation study illustrates that our results can be used in case of small and moderate N and T. We apply our results to detect change in the “corruption index”.     

Model-based confidence bands for survival functions

This paper focuses on a novel method of developing one-sample confidence bands for survival functions from right censored data. The approach is model-based, relying on a parametric model for the conditional expectation of the censoring indicator given the observed minimum, and derives its strength from easy access to a good-fitting model among a plethora of choices available for binary response data. The substantive methodological contribution is in exploiting a semiparametric estimator of the survival function to produce improved simultaneous confidence bands. To obtain critical values for computing the confidence bands, a two-stage bootstrap approach that combines the classical bootstrap with the more recent model-based regeneration of censoring indicators is proposed and a justification of its asymptotic validity is also provided. Several different confidence bands are studied using the proposed approach. Numerical studies, including robustness of the proposed bands to misspecification, are carried out to check efficacy. The method is illustrated using two lung cancer data sets.     

Bayesian inference with misspecified models

This article reviews Bayesian inference from the perspective that the designated model is misspecified. This misspecification has implications in interpretation of objects, such as the prior distribution, which has been the cause of recent questioning of the appropriateness of Bayesian inference in this scenario. The main focus of this article is to establish the suitability of applying the Bayes update to a misspecified model, and relies on representation theorems for sequences of symmetric distributions; the identification of parameter values of interest; and the construction of sequences of distributions which act as the guesses as to where the next observation is coming from. A conclusion is that a clear identification of the fundamental starting point for the Bayesian is described.     

Consistency of maximum likelihood estimators in a large class of deconvolution models

We consider the maximum likelihood estimator $\hat{F}_n$ of a distribution function in a class of deconvolution models where the known density of the noise variable is of bounded variation. This class of noise densities contains in particular bounded, decreasing densities. The estimator $\hat{F}_n$ is defined, characterized in terms of Fenchel optimality conditions and computed. Under appropriate conditions, various consistency results for $\hat{F}_n$ are derived, including uniform strong consistency. The Canadian Journal of Statistics 41: 98–110; 2013 © 2012 Statistical Society of Canada     

Estimation with right‐censored observations under a semi‐Markov model

The semi‐Markov process often provides a better framework than the classical Markov process for the analysis of events with multiple states. The purpose of this paper is twofold. First, we show that in the presence of right censoring, when the right end‐point of the support of the censoring time is strictly less than the right end‐point of the support of the semi‐Markov kernel, the transition probability of the semi‐Markov process is nonidentifiable, and the estimators proposed in the literature are inconsistent in general. We derive the set of all attainable values for the transition probability based on the censored data, and we propose a nonparametric inference procedure for the transition probability using this set. Second, the conventional approach to constructing confidence bands is not applicable for the semi‐Markov kernel and the sojourn time distribution. We propose new perturbation resampling methods to construct these confidence bands. Different weights and transformations are explored in the construction. We use simulation to examine our proposals and illustrate them with hospitalization data from a recent cancer survivor study. The Canadian Journal of Statistics 41: 237–256; 2013 © 2013 Statistical Society of Canada     

关于层次分析法的数值试验

通过对层次分析法进行数值模拟,证实了次序性程度不仅对评价结果存在着显著的影响,而且也与一致性指标存在着密切的关系,同时也证实了标度精度不足是导致多种标度并存的原因,并建议采用适当的标度精度,这一观点与Saaty是一致的。实验结果还清楚地表明,单纯使用一致性指标判定一个矩阵好坏是不够的,应该辅助以其它指标。     

Is a pure jump process fitting the high frequency data better than a jump-diffusion process?

Two families of processes: pure jump processes and jump-diffusion processes are widely used in literatures. Recently, empirical findings demonstrate that the underlying processes of high frequency data sets are pure-jump processes of infinite variation in many situations. Statistical tests are also proposed to make the empirical findings theoretically grounded. In this paper, we extend the work of Jing et al. (2012) in two aspects: (1) the jump process in the null hypothesis and the alternative hypothesis could be different; (2) the null hypothesis covers more flexible processes which are more relevant in finance when considering models for asset prices or nominal interest rates. Theoretically, the test is proven to be very powerful and can control the type I error probabilities well under the nominal level.