Confidence interval estimation of the difference between paired AUCs based on combined biomarkers

In many diagnostic studies, multiple diagnostic tests are performed on each subject or multiple disease markers are available. Commonly, the information should be combined to improve the diagnostic accuracy. We consider the problem of comparing the discriminatory abilities between two groups of biomarkers. Specifically, this article focuses on confidence interval estimation of the difference between paired AUCs based on optimally combined markers under the assumption of multivariate normality. Simulation studies demonstrate that the proposed generalized variable approach provides confidence intervals with satisfying coverage probabilities at finite sample sizes. The proposed method can also easily provide P-values for hypothesis testing. Application to analysis of a subset of data from a study on coronary heart disease illustrates the utility of the method in practice.     

Modified inference about the mean of the exponential distribution using moving extreme ranked set sampling

The maximum likelihood estimator (MLE) and the likelihood ratio test (LRT) will be considered for making inference about the scale parameter of the exponential distribution in case of moving extreme ranked set sampling (MERSS). The MLE and LRT can not be written in closed form. Therefore, a modification of the MLE using the technique suggested by Maharota and Nanda (Biometrika 61:601–606, 1974) will be considered and this modified estimator will be used to modify the LRT to get a test in closed form for testing a simple hypothesis against one sided alternatives. The same idea will be used to modify the most powerful test (MPT) for testing a simple hypothesis versus a simple hypothesis to get a test in closed form for testing a simple hypothesis against one sided alternatives. Then it appears that the modified estimator is a good competitor of the MLE and the modified tests are good competitors of the LRT using MERSS and simple random sampling (SRS).     

中国制造业集聚：度量与显著性检验 ——基于集聚测量新方法

 根据集聚分布的自身特点,本文提出了可以进行显著性检验的普适性产业集聚指数,并对我国28制造业1994年的860个样本和2004年800个样本进行测量和检验,我们的计算结果表明,中国制造业的集聚强度总体上呈上升趋势,同时具有集聚和扩散双重现象。     

政府干预理论:证券监管的必要性和适度性

证券市场具有市场的一般特征,同时具有高风险和高效集资的独有特征.当证券市场同样面临市场失灵的问题时,政府监管部门有责任对市场进行有效干预.在政府宏观干预理论视域下,结合一般市场与证券市场的共性与特性之比较,探讨证券监管的必要性及证券监管"度"的把握,对于优化证券市场具有一定的理论意义和现实意义.     

司法的独立与民主:价值整合和制度架构

司法独立追求法律职业主义和司法规则模型,司法民主注重民众参与和意志表达,法治实践中两者存在紧张关系.应结合后现代社会关系性质和秩序状况,按照法律商谈论理路对司法独立和民主两种实现社会主体权利和自由的方法进行价值整合,确立法官社会化、司法论坛化、司法能动化、解纷机制多元化等制度架构方向.     

缺失数据时两个对数正态分布的估计和检验

讨论了部分缺失数据两对敷正态分布的参数估计和关于总体相同的似然比检验.证明了估计的强相合性和渐近正态性,给出了似然比检验统计量的极限分布,并讨论基于精确分布的检验问题.     

真实不伪:前孟荀时代的人性论--以"眚自命出,命自天降"为基点

以往诸学者一谈及先秦时期的人性论,莫不以孔、孟、苟之“三段论”为要,且易以善恶之伦理范畴来界定之,然自此一时期简帛的出土,为全面、深入地研究先秦人性论提供了珍贵的文献资料与难得的历史机遇。故文章拟以新近出土之简帛,尤其是郭店简《性自命出》篇为史料基点,对先秦人性论付诸以全新、深入之考查,以图对以往学界对先秦人性论贯之以善恶界定之思维范式有所突破,从而向先秦人性论之整体原貌无限趋近。     

互利共赢的博弈论分析

十七大报告指出要“始终不渝奉行互利共赢的开放战略”,博弈论是研究互利共赢问题的有力工具。国际关系中囚徒困境博弈的大量存在提出了互利共赢的必要性;无限重复囚徒困境博弈中合作均衡的实现表明互利共赢是可能的;在现实中合作的实现表明互利共赢是可行的;全球化为互利共赢的实现提供了现实基础;“一报还一报”是实现互利共赢的基本策略。     

审美论-语言论-文化论：新时期30年文论发展轨迹

新时期30年来,经过几代学人的共同努力,文学理论迎来了发展的最好时期。这30年文论的发展轨迹可以粗略概括为：从审美论,到语言论,再到文化论。因此,有必要在审美论、语言论和文化论三元兼摄的“文化诗学”路径中,进一步推动文学理论的研究,使它有更好的发展。     

志气观与行动主义德性观的融通

孟子和亚里士多德作为东方和西方＂轴心时代＂的重要代表,在道德学说上分别提出了＂志气＂观和＂行动主义＂德性观。强烈的实践精神是其道德伦理的融通之处。